TopFIND 4.0

Q86SQ6: Adhesion G protein-coupled receptor A1 {ECO:0000303|PubMed:25713288}

General Information

Protein names
- Adhesion G protein-coupled receptor A1 {ECO:0000303|PubMed:25713288}
- G-protein coupled receptor 123
Gene names GPR123
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q86SQ6

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDLKTVLSLP RYPGEFLHPV VYACTAVMLL CLLASFVTYI VHQSAIRISR KGRHTLLNFC 
        70         80         90        100        110        120 
FHAALTFTVF AGGINRTKYP ILCQAVGIVL HYSTLSTMLW IGVTARNIYK QVTKKAPLCL 
       130        140        150        160        170        180 
DTDQPPYPRQ PLLRFYLVSG GVPFIICGVT AATNIRNYGT EDEDTAYCWM AWEPSLGAFY 
       190        200        210        220        230        240 
GPAAIITLVT CVYFLGTYVQ LRRHPGRRYE LRTQPEEQRR LATPEGGRGI RPGTPPAHDA 
       250        260        270        280        290        300 
PGASVLQNEH SFQAQLRAAA FTLFLFTATW AFGALAVSQG HFLDMVFSCL YGAFCVTLGL 
       310        320        330        340        350        360 
FVLIHHCAKR EDVWQCWWAC CPPRKDAHPA LDANGAALGR AACLHSPGLG QPRGFAHPPG 
       370        380        390        400        410        420 
PCKMTNLQAA QGHASCLSPA TPCCAKMHCE PLTADEAHVH LQEEGAFGHD PHLHGCLQGR 
       430        440        450        460        470        480 
TKPPYFSRHP AEEPEYAYHI PSSLDGSPRS SRTDSPPSSL DGPAGTHTLA CCTQGDPFPM 
       490        500        510        520        530        540 
VTQPEGSDGS PALYSCPTQP GREAALGPGH LEMLRRTQSL PFGGPSQNGL PKGKLLEGLP 
       550        560    
FGTDGTGNIR TGPWKNETTV 

Isoforms

- Isoform 1 of Probable G-protein coupled receptor 123 - Isoform 2 of Probable G-protein coupled receptor 123 - Isoform 1 of Adhesion G protein-coupled receptor A1 - Isoform 2 of Adhesion G protein-coupled receptor A1

Sequence View

        10         20         30         40         50         60 
MDLKTVLSLP RYPGEFLHPV VYACTAVMLL CLLASFVTYI VHQSAIRISR KGRHTLLNFC 
        70         80         90        100        110        120 
FHAALTFTVF AGGINRTKYP ILCQAVGIVL HYSTLSTMLW IGVTARNIYK QVTKKAPLCL 
       130        140        150        160        170        180 
DTDQPPYPRQ PLLRFYLVSG GVPFIICGVT AATNIRNYGT EDEDTAYCWM AWEPSLGAFY 
       190        200        210        220        230        240 
GPAAIITLVT CVYFLGTYVQ LRRHPGRRYE LRTQPEEQRR LATPEGGRGI RPGTPPAHDA 
       250        260        270        280        290        300 
PGASVLQNEH SFQAQLRAAA FTLFLFTATW AFGALAVSQG HFLDMVFSCL YGAFCVTLGL 
       310        320        330        340        350        360 
FVLIHHCAKR EDVWQCWWAC CPPRKDAHPA LDANGAALGR AACLHSPGLG QPRGFAHPPG 
       370        380        390        400        410        420 
PCKMTNLQAA QGHASCLSPA TPCCAKMHCE PLTADEAHVH LQEEGAFGHD PHLHGCLQGR 
       430        440        450        460        470        480 
TKPPYFSRHP AEEPEYAYHI PSSLDGSPRS SRTDSPPSSL DGPAGTHTLA CCTQGDPFPM 
       490        500        510        520        530        540 
VTQPEGSDGS PALYSCPTQP GREAALGPGH LEMLRRTQSL PFGGPSQNGL PKGKLLEGLP 
       550        560    
FGTDGTGNIR TGPWKNETTV          10         20         30         40         50         60 
MDLKTVLSLP RYPGEFLHPV VYACTAVMLL CLLASFVTYI VHQSAIRISR KGRHTLLNFC 
        70         80         90        100        110        120 
FHAALTFTVF AGGINRTKYP ILCQAVGIVL HYSTLSTMLW IGVTARNIYK QVTKKAPLCL 
       130        140        150        160        170        180 
DTDQPPYPRQ PLLRFYLVSG GVPFIICGVT AATNIRNYGT EDEDTAYCWM AWEPSLGAFY 
       190        200        210        220        230        240 
GPAAIITLVT CVYFLGTYVQ LRRHPGRRYE LRTQPEEQRR LATPEGGRGI RPGTPPAHDA 
       250        260        270        280        290        300 
PGASVLQNEH SFQAQLRAAA FTLFLFTATW AFGALAVSQG HFLDMVFSCL YGAFCVTLGL 
       310        320        330        340        350        360 
FVLIHHCAKR EDVWQCWWAC CPPRKDAHPA LDANGAALGR AACLHSPGLG QPRGFAHPPG 
       370        380        390        400        410        420 
PCKMTNLQAA QGHASCLSPA TPCCAKMHCE PLTADEAHVH LQEEGAFGHD PHLHGCLQGR 
       430        440        450        460        470        480 
TKPPYFSRHP AEEPEYAYHI PSSLDGSPRS SRTDSPPSSL DGPAGTHTLA CCTQGDPFPM 
       490        500        510        520        530        540 
VTQPEGSDGS PALYSCPTQP GREAALGPGH LEMLRRTQSL PFGGPSQNGL PKGKLLEGLP 
       550        560    
FGTDGTGNIR TGPWKNETTV          10         20         30         40         50         60 
MDLKTVLSLP RYPGEFLHPV VYACTAVMLL CLLASFVTYI VHQSAIRISR KGRHTLLNFC 
        70         80         90        100        110        120 
FHAALTFTVF AGGINRTKYP ILCQAVGIVL HYSTLSTMLW IGVTARNIYK QVTKKAPLCL 
       130        140        150        160        170        180 
DTDQPPYPRQ PLLRFYLVSG GVPFIICGVT AATNIRNYGT EDEDTAYCWM AWEPSLGAFY 
       190        200        210        220        230        240 
GPAAIITLVT CVYFLGTYVQ LRRHPGRRYE LRTQPEEQRR LATPEGGRGI RPGTPPAHDA 
       250        260        270        280        290        300 
PGASVLQNEH SFQAQLRAAA FTLFLFTATW AFGALAVSQG HFLDMVFSCL YGAFCVTLGL 
       310        320        330        340        350        360 
FVLIHHCAKR EDVWQCWWAC CPPRKDAHPA LDANGAALGR AACLHSPGLG QPRGFAHPPG 
       370        380        390        400        410        420 
PCKMTNLQAA QGHASCLSPA TPCCAKMHCE PLTADEAHVH LQEEGAFGHD PHLHGCLQGR 
       430        440        450        460        470        480 
TKPPYFSRHP AEEPEYAYHI PSSLDGSPRS SRTDSPPSSL DGPAGTHTLA CCTQGDPFPM 
       490        500        510        520        530        540 
VTQPEGSDGS PALYSCPTQP GREAALGPGH LEMLRRTQSL PFGGPSQNGL PKGKLLEGLP 
       550        560    
FGTDGTGNIR TGPWKNETTV          10         20         30         40         50         60 
MDLKTVLSLP RYPGEFLHPV VYACTAVMLL CLLASFVTYI VHQSAIRISR KGRHTLLNFC 
        70         80         90        100        110        120 
FHAALTFTVF AGGINRTKYP ILCQAVGIVL HYSTLSTMLW IGVTARNIYK QVTKKAPLCL 
       130        140        150        160        170        180 
DTDQPPYPRQ PLLRFYLVSG GVPFIICGVT AATNIRNYGT EDEDTAYCWM AWEPSLGAFY 
       190        200        210        220        230        240 
GPAAIITLVT CVYFLGTYVQ LRRHPGRRYE LRTQPEEQRR LATPEGGRGI RPGTPPAHDA 
       250        260        270        280        290        300 
PGASVLQNEH SFQAQLRAAA FTLFLFTATW AFGALAVSQG HFLDMVFSCL YGAFCVTLGL 
       310        320        330        340        350        360 
FVLIHHCAKR EDVWQCWWAC CPPRKDAHPA LDANGAALGR AACLHSPGLG QPRGFAHPPG 
       370        380        390        400        410        420 
PCKMTNLQAA QGHASCLSPA TPCCAKMHCE PLTADEAHVH LQEEGAFGHD PHLHGCLQGR 
       430        440        450        460        470        480 
TKPPYFSRHP AEEPEYAYHI PSSLDGSPRS SRTDSPPSSL DGPAGTHTLA CCTQGDPFPM 
       490        500        510        520        530        540 
VTQPEGSDGS PALYSCPTQP GREAALGPGH LEMLRRTQSL PFGGPSQNGL PKGKLLEGLP 
       550        560    
FGTDGTGNIR TGPWKNETTV 



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q86SQ6-1-unknown MDLKTV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q86SQ6-98-unknown MLWIGV... 98 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt76243

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...NETTV 560 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...NETTV 560 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt71861

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)