TopFIND 4.0

Q86U10: 60 kDa lysophospholipase

General Information

Protein names
- 60 kDa lysophospholipase
- 3.1.1.5
- L-asparaginase
- 3.5.1.1
- L-asparagine amidohydrolase
- Platelet-activating factor acetylhydrolase
- PAF acetylhydrolase
- 3.1.1.47
Gene names ASPG
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q86U10

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MARAVGPERR LLAVYTGGTI GMRSELGVLV PGTGLAAILR TLPMFHDEEH ARARGLSEDT 
        70         80         90        100        110        120 
LVLPPASRNQ RILYTVLECQ PLFDSSDMTI AEWVCLAQTI KRHYEQYHGF VVIHGTDTMA 
       130        140        150        160        170        180 
FAASMLSFML ENLQKTVILT GAQVPIHALW SDGRENLLGA LLMAGQYVIP EVCLFFQNQL 
       190        200        210        220        230        240 
FRGNRATKVD ARRFAAFCSP NLLPLATVGA DITINRELVR KVDGKAGLVV HSSMEQDVGL 
       250        260        270        280        290        300 
LRLYPGIPAA LVRAFLQPPL KGVVMETFGS GNGPTKPDLL QELRVATERG LVIVNCTHCL 
       310        320        330        340        350        360 
QGAVTTDYAA GMAMAGAGVI SGFDMTSEAA LAKLSYVLGQ PGLSLDVRKE LLTKDLRGEM 
       370        380        390        400        410        420 
TPPSVEERRP SLQGNTLGGG VSWLLSLSGS QEADALRNAL VPSLACAAAH AGDVEALQAL 
       430        440        450        460        470        480 
VELGSDLGLV DFNGQTPLHA AARGGHTEAV TMLLQRGVDV NTRDTDGFSP LLLAVRGRHP 
       490        500        510        520        530        540 
GVIGLLREAG ASLSTQELEE AGTELCRLAY RADLEGLQVW WQAGADLGQP GYDGHSALHV 
       550        560        570    
AEAAGNLAVV AFLQSLEGAV GAQAPCPEVL PGV

Isoforms

- Isoform 3 of 60 kDa lysophospholipase

Sequence View

        10         20         30         40         50         60 
MARAVGPERR LLAVYTGGTI GMRSELGVLV PGTGLAAILR TLPMFHDEEH ARARGLSEDT 
        70         80         90        100        110        120 
LVLPPASRNQ RILYTVLECQ PLFDSSDMTI AEWVCLAQTI KRHYEQYHGF VVIHGTDTMA 
       130        140        150        160        170        180 
FAASMLSFML ENLQKTVILT GAQVPIHALW SDGRENLLGA LLMAGQYVIP EVCLFFQNQL 
       190        200        210        220        230        240 
FRGNRATKVD ARRFAAFCSP NLLPLATVGA DITINRELVR KVDGKAGLVV HSSMEQDVGL 
       250        260        270        280        290        300 
LRLYPGIPAA LVRAFLQPPL KGVVMETFGS GNGPTKPDLL QELRVATERG LVIVNCTHCL 
       310        320        330        340        350        360 
QGAVTTDYAA GMAMAGAGVI SGFDMTSEAA LAKLSYVLGQ PGLSLDVRKE LLTKDLRGEM 
       370        380        390        400        410        420 
TPPSVEERRP SLQGNTLGGG VSWLLSLSGS QEADALRNAL VPSLACAAAH AGDVEALQAL 
       430        440        450        460        470        480 
VELGSDLGLV DFNGQTPLHA AARGGHTEAV TMLLQRGVDV NTRDTDGFSP LLLAVRGRHP 
       490        500        510        520        530        540 
GVIGLLREAG ASLSTQELEE AGTELCRLAY RADLEGLQVW WQAGADLGQP GYDGHSALHV 
       550        560        570    
AEAAGNLAVV AFLQSLEGAV GAQAPCPEVL PGV



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Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q86U10-1-unknown MARAVG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q86U10-1-unknown MARAVG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt79831

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VLPGV 573 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)