TopFIND 4.0

Q86UW9: Probable E3 ubiquitin-protein ligase DTX2

General Information

Protein names
- Probable E3 ubiquitin-protein ligase DTX2
- 2.3.2.27 {ECO:0000250|UniProtKB:Q61010}
- Protein deltex-2
- Deltex2
- hDTX2
- RING finger protein 58
- RING-type E3 ubiquitin transferase DTX2 {ECO:0000305}
Gene names DTX2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q86UW9

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAMAPSPSLV QVYTSPAAVA VWEWQDGLGT WHPYSATVCS FIEQQFVQQK GQRFGLGSLA 
        70         80         90        100        110        120 
HSIPLGQADP SLAPYIIDLP SWTQFRQDTG TMRAVRRHLF PQHSAPGRGV VWEWLSDDGS 
       130        140        150        160        170        180 
WTAYEASVCD YLEQQVARGN QLVDLAPLGY NYTVNYTTHT QTNKTSSFCR SVRRQAGPPY 
       190        200        210        220        230        240 
PVTTIIAPPG HTGVACSCHQ CLSGSRTGPV SGRYRHSMTN LPAYPVPQHP PHRTASVFGT 
       250        260        270        280        290        300 
HQAFAPYNKP SLSGARSAPR LNTTNAWGAA PPSLGSQPLY RSSLSHLGPQ HLPPGSSTSG 
       310        320        330        340        350        360 
AVSASLPSGP SSSPGSVPAT VPMQMPKPSR VQQALAGMTS VLMSAIGLPV CLSRAPQPTS 
       370        380        390        400        410        420 
PPASRLASKS HGSVKRLRKM SVKGATPKPE PEPEQVIKNY TEELKVPPDE DCIICMEKLS 
       430        440        450        460        470        480 
TASGYSDVTD SKAIGSLAVG HLTKCSHAFH LLCLLAMYCN GNKDGSLQCP SCKTIYGEKT 
       490        500        510        520        530        540 
GTQPQGKMEV LRFQMSLPGH EDCGTILIVY SIPHGIQGPE HPNPGKPFTA RGFPRQCYLP 
       550        560        570        580        590        600 
DNAQGRKVLE LLKVAWKRRL IFTVGTSSTT GETDTVVWNE IHHKTEMDRN ITGHGYPDPN 
       610        620    
YLQNVLAELA AQGVTEDCLE QQ

Isoforms

- Isoform 2 of Probable E3 ubiquitin-protein ligase DTX2

Sequence View

        10         20         30         40         50         60 
MAMAPSPSLV QVYTSPAAVA VWEWQDGLGT WHPYSATVCS FIEQQFVQQK GQRFGLGSLA 
        70         80         90        100        110        120 
HSIPLGQADP SLAPYIIDLP SWTQFRQDTG TMRAVRRHLF PQHSAPGRGV VWEWLSDDGS 
       130        140        150        160        170        180 
WTAYEASVCD YLEQQVARGN QLVDLAPLGY NYTVNYTTHT QTNKTSSFCR SVRRQAGPPY 
       190        200        210        220        230        240 
PVTTIIAPPG HTGVACSCHQ CLSGSRTGPV SGRYRHSMTN LPAYPVPQHP PHRTASVFGT 
       250        260        270        280        290        300 
HQAFAPYNKP SLSGARSAPR LNTTNAWGAA PPSLGSQPLY RSSLSHLGPQ HLPPGSSTSG 
       310        320        330        340        350        360 
AVSASLPSGP SSSPGSVPAT VPMQMPKPSR VQQALAGMTS VLMSAIGLPV CLSRAPQPTS 
       370        380        390        400        410        420 
PPASRLASKS HGSVKRLRKM SVKGATPKPE PEPEQVIKNY TEELKVPPDE DCIICMEKLS 
       430        440        450        460        470        480 
TASGYSDVTD SKAIGSLAVG HLTKCSHAFH LLCLLAMYCN GNKDGSLQCP SCKTIYGEKT 
       490        500        510        520        530        540 
GTQPQGKMEV LRFQMSLPGH EDCGTILIVY SIPHGIQGPE HPNPGKPFTA RGFPRQCYLP 
       550        560        570        580        590        600 
DNAQGRKVLE LLKVAWKRRL IFTVGTSSTT GETDTVVWNE IHHKTEMDRN ITGHGYPDPN 
       610        620    
YLQNVLAELA AQGVTEDCLE QQ



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q86UW9-1-unknown MAMAPS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q86UW9-1-unknown MAMAPS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73334

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...CLEQQ 622 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...CLEQQ 622 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt68952

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)