TopFIND 4.0

Q86V21: Acetoacetyl-CoA synthetase

General Information

Protein names
- Acetoacetyl-CoA synthetase
- 6.2.1.16
- Acyl-CoA synthetase family member 1
- Protein sur-5 homolog
Gene names AACS
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q86V21

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSKEERPGRE EILECQVMWE PDSKKNTQMD RFRAAVGAAC GLALESYDDL YHWSVESYSD 
        70         80         90        100        110        120 
FWAEFWKFSG IVFSRVYDEV VDTSKGIADV PEWFKGSRLN YAENLLRHKE NDRVALYIAR 
       130        140        150        160        170        180 
EGKEEIVKVT FEELRQEVAL FAAAMRKMGV KKGDRVVGYL PNSEHAVEAM LAAASIGAIW 
       190        200        210        220        230        240 
SSTSPDFGVN GVLDRFSQIQ PKLIFSVEAV VYNGKEHNHM EKLQQVVKGL PDLKKVVVIP 
       250        260        270        280        290        300 
YVSSRENIDL SKIPNSVFLD DFLATGTSEQ APQLEFEQLP FSHPLFIMFS SGTTGAPKCM 
       310        320        330        340        350        360 
VHSAGGTLIQ HLKEHLLHGN MTSSDILLCY TTVGWMMWNW MVSLLATGAA MVLYDGSPLV 
       370        380        390        400        410        420 
PTPNVLWDLV DRIGITVLVT GAKWLSVLEE KAMKPVETHS LQMLHTILST GSPLKAQSYE 
       430        440        450        460        470        480 
YVYRCIKSSI LLGSISGGTD IISCFMGHNF SLPVYKGEIQ ARNLGMAVEA WNEEGKAVWG 
       490        500        510        520        530        540 
ESGELVCTKP IPCQPTHFWN DENGNKYRKA YFSKFPGIWA HGDYCRINPK TGGIVMLGRS 
       550        560        570        580        590        600 
DGTLNPNGVR FGSSEIYNIV ESFEEVEDSL CVPQYNKYRE ERVILFLKMA SGHAFQPDLV 
       610        620        630        640        650        660 
KRIRDAIRMG LSARHVPSLI LETKGIPYTL NGKKVEVAVK QIIAGKAVEQ GGAFSNPETL 
       670    
DLYRDIPELQ GF

Isoforms

- Isoform 2 of Acetoacetyl-CoA synthetase - Isoform 3 of Acetoacetyl-CoA synthetase

Sequence View

        10         20         30         40         50         60 
MSKEERPGRE EILECQVMWE PDSKKNTQMD RFRAAVGAAC GLALESYDDL YHWSVESYSD 
        70         80         90        100        110        120 
FWAEFWKFSG IVFSRVYDEV VDTSKGIADV PEWFKGSRLN YAENLLRHKE NDRVALYIAR 
       130        140        150        160        170        180 
EGKEEIVKVT FEELRQEVAL FAAAMRKMGV KKGDRVVGYL PNSEHAVEAM LAAASIGAIW 
       190        200        210        220        230        240 
SSTSPDFGVN GVLDRFSQIQ PKLIFSVEAV VYNGKEHNHM EKLQQVVKGL PDLKKVVVIP 
       250        260        270        280        290        300 
YVSSRENIDL SKIPNSVFLD DFLATGTSEQ APQLEFEQLP FSHPLFIMFS SGTTGAPKCM 
       310        320        330        340        350        360 
VHSAGGTLIQ HLKEHLLHGN MTSSDILLCY TTVGWMMWNW MVSLLATGAA MVLYDGSPLV 
       370        380        390        400        410        420 
PTPNVLWDLV DRIGITVLVT GAKWLSVLEE KAMKPVETHS LQMLHTILST GSPLKAQSYE 
       430        440        450        460        470        480 
YVYRCIKSSI LLGSISGGTD IISCFMGHNF SLPVYKGEIQ ARNLGMAVEA WNEEGKAVWG 
       490        500        510        520        530        540 
ESGELVCTKP IPCQPTHFWN DENGNKYRKA YFSKFPGIWA HGDYCRINPK TGGIVMLGRS 
       550        560        570        580        590        600 
DGTLNPNGVR FGSSEIYNIV ESFEEVEDSL CVPQYNKYRE ERVILFLKMA SGHAFQPDLV 
       610        620        630        640        650        660 
KRIRDAIRMG LSARHVPSLI LETKGIPYTL NGKKVEVAVK QIIAGKAVEQ GGAFSNPETL 
       670    
DLYRDIPELQ GF         10         20         30         40         50         60 
MSKEERPGRE EILECQVMWE PDSKKNTQMD RFRAAVGAAC GLALESYDDL YHWSVESYSD 
        70         80         90        100        110        120 
FWAEFWKFSG IVFSRVYDEV VDTSKGIADV PEWFKGSRLN YAENLLRHKE NDRVALYIAR 
       130        140        150        160        170        180 
EGKEEIVKVT FEELRQEVAL FAAAMRKMGV KKGDRVVGYL PNSEHAVEAM LAAASIGAIW 
       190        200        210        220        230        240 
SSTSPDFGVN GVLDRFSQIQ PKLIFSVEAV VYNGKEHNHM EKLQQVVKGL PDLKKVVVIP 
       250        260        270        280        290        300 
YVSSRENIDL SKIPNSVFLD DFLATGTSEQ APQLEFEQLP FSHPLFIMFS SGTTGAPKCM 
       310        320        330        340        350        360 
VHSAGGTLIQ HLKEHLLHGN MTSSDILLCY TTVGWMMWNW MVSLLATGAA MVLYDGSPLV 
       370        380        390        400        410        420 
PTPNVLWDLV DRIGITVLVT GAKWLSVLEE KAMKPVETHS LQMLHTILST GSPLKAQSYE 
       430        440        450        460        470        480 
YVYRCIKSSI LLGSISGGTD IISCFMGHNF SLPVYKGEIQ ARNLGMAVEA WNEEGKAVWG 
       490        500        510        520        530        540 
ESGELVCTKP IPCQPTHFWN DENGNKYRKA YFSKFPGIWA HGDYCRINPK TGGIVMLGRS 
       550        560        570        580        590        600 
DGTLNPNGVR FGSSEIYNIV ESFEEVEDSL CVPQYNKYRE ERVILFLKMA SGHAFQPDLV 
       610        620        630        640        650        660 
KRIRDAIRMG LSARHVPSLI LETKGIPYTL NGKKVEVAVK QIIAGKAVEQ GGAFSNPETL 
       670    
DLYRDIPELQ GF



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Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q86V21-1-unknown MSKEER... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q86V21-1-unknown MSKEER... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt65880
    Q86V21-403-unknown MLHTIL... 403 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt65881
    Q86V21-403-unknown MLHTIL... 403 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt100924

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)