TopFIND 4.0

Q86V40: Metalloprotease TIKI1

General Information

Protein names
- Metalloprotease TIKI1
- 3.4.-.-
- TRAB domain-containing protein 2A
Gene names TRABD2A
Organism Homo sapiens
Protease Family M96.001
Protease ID M96.001
Chromosome location
UniProt ID Q86V40

2

N-termini

1

C-termini

0

Cleavages

2

Substrates

Sequence

        10         20         30         40         50         60 
MSPWSWFLLQ TLCLLPTGAA SRRGAPGTAN CELKPQQSEL NSFLWTIKRD PPSYFFGTIH 
        70         80         90        100        110        120 
VPYTRVWDFI PDNSKEAFLQ SSIVYFELDL TDPYTISALT SCQMLPQGEN LQDVLPRDIY 
       130        140        150        160        170        180 
CRLKRHLEYV KLMMPLWMTP DQRGKGLYAD YLFNAIAGNW ERKRPVWVML MVNSLTEVDI 
       190        200        210        220        230        240 
KSRGVPVLDL FLAQEAERLR KQTGAVEKVE EQCHPLNGLN FSQVIFALNQ TLLQQESLRA 
       250        260        270        280        290        300 
GSLQIPYTTE DLIKHYNCGD LSSVILSHDS SQVPNFINAT LPPQERITAQ EIDSYLRREL 
       310        320        330        340        350        360 
IYKRNERIGK RVKALLEEFP DKGFFFAFGA GHFMGNNTVL DVLRREGYEV EHAPAGRPIH 
       370        380        390        400        410        420 
KGKSKKTSTR PTLSTIFAPK VPTLEVPAPE AVSSGHSTLP PLVSRPGSAD TPSEAEQRFR 
       430        440        450        460        470        480 
KKRRRSQRRP RLRQFSDLWV RLEESDIVPQ LQVPVLDRHI STELRLPRRG HSHHSQMVAS 
       490        500    
SACLSLWTPV FWVLVLAFQT ETPLL

Isoforms

- Isoform 2 of Metalloprotease TIKI1

Sequence View

        10         20         30         40         50         60 
MSPWSWFLLQ TLCLLPTGAA SRRGAPGTAN CELKPQQSEL NSFLWTIKRD PPSYFFGTIH 
        70         80         90        100        110        120 
VPYTRVWDFI PDNSKEAFLQ SSIVYFELDL TDPYTISALT SCQMLPQGEN LQDVLPRDIY 
       130        140        150        160        170        180 
CRLKRHLEYV KLMMPLWMTP DQRGKGLYAD YLFNAIAGNW ERKRPVWVML MVNSLTEVDI 
       190        200        210        220        230        240 
KSRGVPVLDL FLAQEAERLR KQTGAVEKVE EQCHPLNGLN FSQVIFALNQ TLLQQESLRA 
       250        260        270        280        290        300 
GSLQIPYTTE DLIKHYNCGD LSSVILSHDS SQVPNFINAT LPPQERITAQ EIDSYLRREL 
       310        320        330        340        350        360 
IYKRNERIGK RVKALLEEFP DKGFFFAFGA GHFMGNNTVL DVLRREGYEV EHAPAGRPIH 
       370        380        390        400        410        420 
KGKSKKTSTR PTLSTIFAPK VPTLEVPAPE AVSSGHSTLP PLVSRPGSAD TPSEAEQRFR 
       430        440        450        460        470        480 
KKRRRSQRRP RLRQFSDLWV RLEESDIVPQ LQVPVLDRHI STELRLPRRG HSHHSQMVAS 
       490        500    
SACLSLWTPV FWVLVLAFQT ETPLL



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 2 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q86V40-1-unknown MSPWSW... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt92173
    Q86V40-20-unknown ASRRGA... 20 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q86V40-20-unknown ASRRGA... 20 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt112404

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ETPLL 505 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ETPLL 505 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt87791

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates