Q86VP3: Phosphofurin acidic cluster sorting protein 2

General Information

Protein names	- Phosphofurin acidic cluster sorting protein 2 - PACS-2 - PACS1-like protein
Gene names	PACS2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q86VP3

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Phosphofurin acidic cluster sorting protein 2 - Isoform 3 of Phosphofurin acidic cluster sorting protein 2 - Isoform 4 of Phosphofurin acidic cluster sorting protein 2

Sequence View

        10         20         30         40         50         60
MAERGRLGLP GAPGALNTPV PMNLFATWEV DGSSPSCVPR LCSLTLKKLV VFKELEKELI
        70         80         90        100        110        120
SVVIAVKMQG SKRILRSHEI VLPPSGQVET DLALTFSLQY PHFLKREGNK LQIMLQRRKR
       130        140        150        160        170        180
YKNRTILGYK TLAAGSISMA EVMQHPSEGG QVLSLCSSIK EAPVKAAEIW IASLSSQPID
       190        200        210        220        230        240
HEDSTMQAGP KAKSTDNYSE EEYESFSSEQ EASDDAVQGQ DLDEDDFDVG KPKKQRRSIV
       250        260        270        280        290        300
RTTSMTRQQN FKQKVVALLR RFKVSDEVLD SEQDPAEHIP EAEEDLDLLY DTLDMEHPSD
       310        320        330        340        350        360
SGPDMEDDDS VLSTPKPKLR PYFEGLSHSS SQTEIGSIHS ARSHKEPPSP ADVPEKTRSL
       370        380        390        400        410        420
GGRQPSDSVS DTVALGVPGP REHPGQPEDS PEAEASTLDV FTERLPPSGR ITKTESLVIP
       430        440        450        460        470        480
STRSEGKQAG RRGRSTSLKE RQAARPQNER ANSLDNERCP DARSQLQIPR KTVYDQLNHI
       490        500        510        520        530        540
LISDDQLPEN IILVNTSDWQ GQFLSDVLQR HTLPVVCTCS PADVQAAFST IVSRIQRYCN
       550        560        570        580        590        600
CNSQPPTPVK IAVAGAQHYL SAILRLFVEQ LSHKTPDWLG YMRFLVIPLG SHPVARYLGS
       610        620        630        640        650        660
VDYRYNNFFQ DLAWRDLFNK LEAQSAVQDT PDIVSRITQY IAGANCAHQL PIAEAMLTYK
       670        680        690        700        710        720
QKSPDEESSQ KFIPFVGVVK VGIVEPSSAT SGDSDDAAPS GSGTLSSTPP SASPAAKEAS
       730        740        750        760        770        780
PTPPSSPSVS GGLSSPSQGV GAELMGLQVD YWTAAQPADR KRDAEKKDLP VTKNTLKCTF
       790        800        810        820        830        840
RSLQVSRLPS SGEAAATPTM SMTVVTKEKN KKVMFLPKKA KDKDVESKSQ CIEGISRLIC
       850        860        870        880
TARQQQNMLR VLIDGVECSD VKFFQLAAQW SSHVKHFPIC IFGHSKATF         10         20         30         40         50         60
MAERGRLGLP GAPGALNTPV PMNLFATWEV DGSSPSCVPR LCSLTLKKLV VFKELEKELI
        70         80         90        100        110        120
SVVIAVKMQG SKRILRSHEI VLPPSGQVET DLALTFSLQY PHFLKREGNK LQIMLQRRKR
       130        140        150        160        170        180
YKNRTILGYK TLAAGSISMA EVMQHPSEGG QVLSLCSSIK EAPVKAAEIW IASLSSQPID
       190        200        210        220        230        240
HEDSTMQAGP KAKSTDNYSE EEYESFSSEQ EASDDAVQGQ DLDEDDFDVG KPKKQRRSIV
       250        260        270        280        290        300
RTTSMTRQQN FKQKVVALLR RFKVSDEVLD SEQDPAEHIP EAEEDLDLLY DTLDMEHPSD
       310        320        330        340        350        360
SGPDMEDDDS VLSTPKPKLR PYFEGLSHSS SQTEIGSIHS ARSHKEPPSP ADVPEKTRSL
       370        380        390        400        410        420
GGRQPSDSVS DTVALGVPGP REHPGQPEDS PEAEASTLDV FTERLPPSGR ITKTESLVIP
       430        440        450        460        470        480
STRSEGKQAG RRGRSTSLKE RQAARPQNER ANSLDNERCP DARSQLQIPR KTVYDQLNHI
       490        500        510        520        530        540
LISDDQLPEN IILVNTSDWQ GQFLSDVLQR HTLPVVCTCS PADVQAAFST IVSRIQRYCN
       550        560        570        580        590        600
CNSQPPTPVK IAVAGAQHYL SAILRLFVEQ LSHKTPDWLG YMRFLVIPLG SHPVARYLGS
       610        620        630        640        650        660
VDYRYNNFFQ DLAWRDLFNK LEAQSAVQDT PDIVSRITQY IAGANCAHQL PIAEAMLTYK
       670        680        690        700        710        720
QKSPDEESSQ KFIPFVGVVK VGIVEPSSAT SGDSDDAAPS GSGTLSSTPP SASPAAKEAS
       730        740        750        760        770        780
PTPPSSPSVS GGLSSPSQGV GAELMGLQVD YWTAAQPADR KRDAEKKDLP VTKNTLKCTF
       790        800        810        820        830        840
RSLQVSRLPS SGEAAATPTM SMTVVTKEKN KKVMFLPKKA KDKDVESKSQ CIEGISRLIC
       850        860        870        880
TARQQQNMLR VLIDGVECSD VKFFQLAAQW SSHVKHFPIC IFGHSKATF         10         20         30         40         50         60
MAERGRLGLP GAPGALNTPV PMNLFATWEV DGSSPSCVPR LCSLTLKKLV VFKELEKELI
        70         80         90        100        110        120
SVVIAVKMQG SKRILRSHEI VLPPSGQVET DLALTFSLQY PHFLKREGNK LQIMLQRRKR
       130        140        150        160        170        180
YKNRTILGYK TLAAGSISMA EVMQHPSEGG QVLSLCSSIK EAPVKAAEIW IASLSSQPID
       190        200        210        220        230        240
HEDSTMQAGP KAKSTDNYSE EEYESFSSEQ EASDDAVQGQ DLDEDDFDVG KPKKQRRSIV
       250        260        270        280        290        300
RTTSMTRQQN FKQKVVALLR RFKVSDEVLD SEQDPAEHIP EAEEDLDLLY DTLDMEHPSD
       310        320        330        340        350        360
SGPDMEDDDS VLSTPKPKLR PYFEGLSHSS SQTEIGSIHS ARSHKEPPSP ADVPEKTRSL
       370        380        390        400        410        420
GGRQPSDSVS DTVALGVPGP REHPGQPEDS PEAEASTLDV FTERLPPSGR ITKTESLVIP
       430        440        450        460        470        480
STRSEGKQAG RRGRSTSLKE RQAARPQNER ANSLDNERCP DARSQLQIPR KTVYDQLNHI
       490        500        510        520        530        540
LISDDQLPEN IILVNTSDWQ GQFLSDVLQR HTLPVVCTCS PADVQAAFST IVSRIQRYCN
       550        560        570        580        590        600
CNSQPPTPVK IAVAGAQHYL SAILRLFVEQ LSHKTPDWLG YMRFLVIPLG SHPVARYLGS
       610        620        630        640        650        660
VDYRYNNFFQ DLAWRDLFNK LEAQSAVQDT PDIVSRITQY IAGANCAHQL PIAEAMLTYK
       670        680        690        700        710        720
QKSPDEESSQ KFIPFVGVVK VGIVEPSSAT SGDSDDAAPS GSGTLSSTPP SASPAAKEAS
       730        740        750        760        770        780
PTPPSSPSVS GGLSSPSQGV GAELMGLQVD YWTAAQPADR KRDAEKKDLP VTKNTLKCTF
       790        800        810        820        830        840
RSLQVSRLPS SGEAAATPTM SMTVVTKEKN KKVMFLPKKA KDKDVESKSQ CIEGISRLIC
       850        860        870        880
TARQQQNMLR VLIDGVECSD VKFFQLAAQW SSHVKHFPIC IFGHSKATF

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q86VP3-1-unknown	MAERGR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q86VP3-1-unknown	MAERGR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt84152
Q86VP3-68-unknown	MQGSKR...	68	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt84154
Q86VP3-68-unknown	MQGSKR...	68	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000393524
Q86VP3-68-unknown	MQGSKR...	68	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000447229
Q86VP3-68-unknown	MQGSKR...	68	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106294
Q86VP3-68-unknown	MQGSKR...	68	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106293
Q86VP3-800-unknown	MSMTVV...	800	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000447544
Q86VP3-800-unknown	MSMTVV...	800	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt200317
Q86VP3-800-unknown	MSMTVV...	800	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt200318
Q86VP3-800-unknown	MSMTVV...	800	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt200319

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GGQVLS	153	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000447229
...GGQVLS	153	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154993
...GGQVLS	153	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154995
...GGQVLS	153	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154994
...SKATF	889	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SKATF	889	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79772
...SKATF	889	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79771
...SKATF	889	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79770

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)