TopFIND 4.0

Q86VQ3: Thioredoxin domain-containing protein 2

General Information

Protein names
- Thioredoxin domain-containing protein 2
- Spermatid-specific thioredoxin-1
- Sptrx-1
Gene names TXNDC2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q86VQ3

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDVDKELGME SVKAGASGKP EMRLGTQEET SEGDANESSL LVLSSNVPLL ALEFLEIAQA 
        70         80         90        100        110        120 
KEKAFLPMVS HTFHMRTEES DASQEGDDLP KSSANTSHPK QDDSPKSSEE TIQPKEGDIP 
       130        140        150        160        170        180 
KAPEETIQSK KEDLPKSSEK AIQPKESNIP KSSAKPIQPK LGNIPKASVK PSQPKEGDIP 
       190        200        210        220        230        240 
KAPEETIQSK KEDLPKSSEE AIQPKEGDIP KSSAKPIQPK LGNIAKTSVK PSQPKESDIP 
       250        260        270        280        290        300 
KSPEETIQPK EGDIPKSSAK PIQPKLGNIP KASVKPSQPK EGDISKSPEE AIQPKEGDLP 
       310        320        330        340        350        360 
KSLEEAIQPK EGDIPKSPEE AIQPKEGDIP KSLEEAIQPK EGDIPKSPEE TIQPKKGDIP 
       370        380        390        400        410        420 
KSPEEAIQPK EGDIPKSPKQ AIQPKEGDIP KSLEEAIPPK EIDIPKSPEE TIQPKEDDSP 
       430        440        450        460        470        480 
KSLEEATPSK EGDILKPEEE TMEFPEGDKV KVILSKEDFE ASLKEAGERL VAVDFSATWC 
       490        500        510        520        530        540 
GPCRTIRPFF HALSVKHEDV VFLEVDADNC EEVVRECAIM CVPTFQFYKK EEKVDELCGA 
       550    
LKEKLEAVIA ELK

Isoforms

- Isoform 2 of Thioredoxin domain-containing protein 2 - Isoform 3 of Thioredoxin domain-containing protein 2

Sequence View

        10         20         30         40         50         60 
MDVDKELGME SVKAGASGKP EMRLGTQEET SEGDANESSL LVLSSNVPLL ALEFLEIAQA 
        70         80         90        100        110        120 
KEKAFLPMVS HTFHMRTEES DASQEGDDLP KSSANTSHPK QDDSPKSSEE TIQPKEGDIP 
       130        140        150        160        170        180 
KAPEETIQSK KEDLPKSSEK AIQPKESNIP KSSAKPIQPK LGNIPKASVK PSQPKEGDIP 
       190        200        210        220        230        240 
KAPEETIQSK KEDLPKSSEE AIQPKEGDIP KSSAKPIQPK LGNIAKTSVK PSQPKESDIP 
       250        260        270        280        290        300 
KSPEETIQPK EGDIPKSSAK PIQPKLGNIP KASVKPSQPK EGDISKSPEE AIQPKEGDLP 
       310        320        330        340        350        360 
KSLEEAIQPK EGDIPKSPEE AIQPKEGDIP KSLEEAIQPK EGDIPKSPEE TIQPKKGDIP 
       370        380        390        400        410        420 
KSPEEAIQPK EGDIPKSPKQ AIQPKEGDIP KSLEEAIPPK EIDIPKSPEE TIQPKEDDSP 
       430        440        450        460        470        480 
KSLEEATPSK EGDILKPEEE TMEFPEGDKV KVILSKEDFE ASLKEAGERL VAVDFSATWC 
       490        500        510        520        530        540 
GPCRTIRPFF HALSVKHEDV VFLEVDADNC EEVVRECAIM CVPTFQFYKK EEKVDELCGA 
       550    
LKEKLEAVIA ELK         10         20         30         40         50         60 
MDVDKELGME SVKAGASGKP EMRLGTQEET SEGDANESSL LVLSSNVPLL ALEFLEIAQA 
        70         80         90        100        110        120 
KEKAFLPMVS HTFHMRTEES DASQEGDDLP KSSANTSHPK QDDSPKSSEE TIQPKEGDIP 
       130        140        150        160        170        180 
KAPEETIQSK KEDLPKSSEK AIQPKESNIP KSSAKPIQPK LGNIPKASVK PSQPKEGDIP 
       190        200        210        220        230        240 
KAPEETIQSK KEDLPKSSEE AIQPKEGDIP KSSAKPIQPK LGNIAKTSVK PSQPKESDIP 
       250        260        270        280        290        300 
KSPEETIQPK EGDIPKSSAK PIQPKLGNIP KASVKPSQPK EGDISKSPEE AIQPKEGDLP 
       310        320        330        340        350        360 
KSLEEAIQPK EGDIPKSPEE AIQPKEGDIP KSLEEAIQPK EGDIPKSPEE TIQPKKGDIP 
       370        380        390        400        410        420 
KSPEEAIQPK EGDIPKSPKQ AIQPKEGDIP KSLEEAIPPK EIDIPKSPEE TIQPKEDDSP 
       430        440        450        460        470        480 
KSLEEATPSK EGDILKPEEE TMEFPEGDKV KVILSKEDFE ASLKEAGERL VAVDFSATWC 
       490        500        510        520        530        540 
GPCRTIRPFF HALSVKHEDV VFLEVDADNC EEVVRECAIM CVPTFQFYKK EEKVDELCGA 
       550    
LKEKLEAVIA ELK



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q86VQ3-1-unknown MDVDKE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q86VQ3-1-unknown MDVDKE... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93474
    Q86VQ3-68-unknown MVSHTF... 68 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93473
    Q86VQ3-68-unknown MVSHTF... 68 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt97790

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)