TopFIND 4.0

Q86WT6: E3 ubiquitin-protein ligase TRIM69

General Information

Protein names
- E3 ubiquitin-protein ligase TRIM69
- 2.3.2.27
- RFP-like domain-containing protein trimless
- RING finger protein 36
- RING-type E3 ubiquitin transferase TRIM69 {ECO:0000305}
- Tripartite motif-containing protein 69
Gene names TRIM69
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q86WT6

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEVSTNPSSN IDPGDYVEMN DSITHLPSKV VIQDITMELH CPLCNDWFRD PLMLSCGHNF 
        70         80         90        100        110        120 
CEACIQDFWR LQAKETFCPE CKMLCQYNNC TFNPVLDKLV EKIKKLPLLK GHPQCPEHGE 
       130        140        150        160        170        180 
NLKLFSKPDG KLICFQCKDA RLSVGQSKEF LQISDAVHFF TEELAIQQGQ LETTLKELQT 
       190        200        210        220        230        240 
LRNMQKEAIA AHKENKLHLQ QHVSMEFLKL HQFLHSKEKD ILTELREEGK ALNEEMELNL 
       250        260        270        280        290        300 
SQLQEQCLLA KDMLVSIQAK TEQQNSFDFL KDITTLLHSL EQGMKVLATR ELISRKLNLG 
       310        320        330        340        350        360 
QYKGPIQYMV WREMQDTLCP GLSPLTLDPK TAHPNLVLSK SQTSVWHGDI KKIMPDDPER 
       370        380        390        400        410        420 
FDSSVAVLGS RGFTSGKWYW EVEVAKKTKW TVGVVRESII RKGSCPLTPE QGFWLLRLRN 
       430        440        450        460        470        480 
QTDLKALDLP SFSLTLTNNL DKVGIYLDYE GGQLSFYNAK TMTHIYTFSN TFMEKLYPYF 
       490        500    
CPCLNDGGEN KEPLHILHPQ 

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase TRIM69 - Isoform 3 of E3 ubiquitin-protein ligase TRIM69 - Isoform 4 of E3 ubiquitin-protein ligase TRIM69

Sequence View

        10         20         30         40         50         60 
MEVSTNPSSN IDPGDYVEMN DSITHLPSKV VIQDITMELH CPLCNDWFRD PLMLSCGHNF 
        70         80         90        100        110        120 
CEACIQDFWR LQAKETFCPE CKMLCQYNNC TFNPVLDKLV EKIKKLPLLK GHPQCPEHGE 
       130        140        150        160        170        180 
NLKLFSKPDG KLICFQCKDA RLSVGQSKEF LQISDAVHFF TEELAIQQGQ LETTLKELQT 
       190        200        210        220        230        240 
LRNMQKEAIA AHKENKLHLQ QHVSMEFLKL HQFLHSKEKD ILTELREEGK ALNEEMELNL 
       250        260        270        280        290        300 
SQLQEQCLLA KDMLVSIQAK TEQQNSFDFL KDITTLLHSL EQGMKVLATR ELISRKLNLG 
       310        320        330        340        350        360 
QYKGPIQYMV WREMQDTLCP GLSPLTLDPK TAHPNLVLSK SQTSVWHGDI KKIMPDDPER 
       370        380        390        400        410        420 
FDSSVAVLGS RGFTSGKWYW EVEVAKKTKW TVGVVRESII RKGSCPLTPE QGFWLLRLRN 
       430        440        450        460        470        480 
QTDLKALDLP SFSLTLTNNL DKVGIYLDYE GGQLSFYNAK TMTHIYTFSN TFMEKLYPYF 
       490        500    
CPCLNDGGEN KEPLHILHPQ          10         20         30         40         50         60 
MEVSTNPSSN IDPGDYVEMN DSITHLPSKV VIQDITMELH CPLCNDWFRD PLMLSCGHNF 
        70         80         90        100        110        120 
CEACIQDFWR LQAKETFCPE CKMLCQYNNC TFNPVLDKLV EKIKKLPLLK GHPQCPEHGE 
       130        140        150        160        170        180 
NLKLFSKPDG KLICFQCKDA RLSVGQSKEF LQISDAVHFF TEELAIQQGQ LETTLKELQT 
       190        200        210        220        230        240 
LRNMQKEAIA AHKENKLHLQ QHVSMEFLKL HQFLHSKEKD ILTELREEGK ALNEEMELNL 
       250        260        270        280        290        300 
SQLQEQCLLA KDMLVSIQAK TEQQNSFDFL KDITTLLHSL EQGMKVLATR ELISRKLNLG 
       310        320        330        340        350        360 
QYKGPIQYMV WREMQDTLCP GLSPLTLDPK TAHPNLVLSK SQTSVWHGDI KKIMPDDPER 
       370        380        390        400        410        420 
FDSSVAVLGS RGFTSGKWYW EVEVAKKTKW TVGVVRESII RKGSCPLTPE QGFWLLRLRN 
       430        440        450        460        470        480 
QTDLKALDLP SFSLTLTNNL DKVGIYLDYE GGQLSFYNAK TMTHIYTFSN TFMEKLYPYF 
       490        500    
CPCLNDGGEN KEPLHILHPQ          10         20         30         40         50         60 
MEVSTNPSSN IDPGDYVEMN DSITHLPSKV VIQDITMELH CPLCNDWFRD PLMLSCGHNF 
        70         80         90        100        110        120 
CEACIQDFWR LQAKETFCPE CKMLCQYNNC TFNPVLDKLV EKIKKLPLLK GHPQCPEHGE 
       130        140        150        160        170        180 
NLKLFSKPDG KLICFQCKDA RLSVGQSKEF LQISDAVHFF TEELAIQQGQ LETTLKELQT 
       190        200        210        220        230        240 
LRNMQKEAIA AHKENKLHLQ QHVSMEFLKL HQFLHSKEKD ILTELREEGK ALNEEMELNL 
       250        260        270        280        290        300 
SQLQEQCLLA KDMLVSIQAK TEQQNSFDFL KDITTLLHSL EQGMKVLATR ELISRKLNLG 
       310        320        330        340        350        360 
QYKGPIQYMV WREMQDTLCP GLSPLTLDPK TAHPNLVLSK SQTSVWHGDI KKIMPDDPER 
       370        380        390        400        410        420 
FDSSVAVLGS RGFTSGKWYW EVEVAKKTKW TVGVVRESII RKGSCPLTPE QGFWLLRLRN 
       430        440        450        460        470        480 
QTDLKALDLP SFSLTLTNNL DKVGIYLDYE GGQLSFYNAK TMTHIYTFSN TFMEKLYPYF 
       490        500    
CPCLNDGGEN KEPLHILHPQ 



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Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q86WT6-1-unknown MEVSTN... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q86WT6-205-unknown MEFLKL... 205 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93052
    Q86WT6-205-unknown MEFLKL... 205 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93053
    Q86WT6-205-unknown MEFLKL... 205 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt102963

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)