TopFIND 4.0

Q86WU2: Probable D-lactate dehydrogenase, mitochondrial

General Information

Protein names
- Probable D-lactate dehydrogenase, mitochondrial
- DLD
- Lactate dehydrogenase D
- 1.1.2.4
Gene names LDHD
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q86WU2

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MARLLRSATW ELFPWRGYCS QKAKGELCRD FVEALKAVVG GSHVSTAAVV REQHGRDESV 
        70         80         90        100        110        120 
HRCEPPDAVV WPQNVEQVSR LAALCYRQGV PIIPFGTGTG LEGGVCAVQG GVCVNLTHMD 
       130        140        150        160        170        180 
RILELNQEDF SVVVEPGVTR KALNAHLRDS GLWFPVDPGA DASLCGMAAT GASGTNAVRY 
       190        200        210        220        230        240 
GTMRDNVLNL EVVLPDGRLL HTAGRGRHFR FGFWPEIPHH TAWYSPCVSL GRRKSAAGYN 
       250        260        270        280        290        300 
LTGLFVGSEG TLGLITATTL RLHPAPEATV AATCAFPSVQ AAVDSTVHIL QAAVPVARIE 
       310        320        330        340        350        360 
FLDEVMMDAC NRYSKLNCLV APTLFLEFHG SQQALEEQLQ RTEEIVQQNG ASDFSWAKEA 
       370        380        390        400        410        420 
EERSRLWTAR HNAWYAALAT RPGCKGYSTD VCVPISRLPE IVVQTKEDLN ASGLTGSIVG 
       430        440        450        460        470        480 
HVGDGNFHCI LLVNPDDAEE LGRVKAFAEQ LGRRALALHG TCTGEHGIGM GKRQLLQEEV 
       490        500    
GAVGVETMRQ LKAVLDPQGL MNPGKVL

Isoforms

- Isoform 2 of Probable D-lactate dehydrogenase, mitochondrial

Sequence View

        10         20         30         40         50         60 
MARLLRSATW ELFPWRGYCS QKAKGELCRD FVEALKAVVG GSHVSTAAVV REQHGRDESV 
        70         80         90        100        110        120 
HRCEPPDAVV WPQNVEQVSR LAALCYRQGV PIIPFGTGTG LEGGVCAVQG GVCVNLTHMD 
       130        140        150        160        170        180 
RILELNQEDF SVVVEPGVTR KALNAHLRDS GLWFPVDPGA DASLCGMAAT GASGTNAVRY 
       190        200        210        220        230        240 
GTMRDNVLNL EVVLPDGRLL HTAGRGRHFR FGFWPEIPHH TAWYSPCVSL GRRKSAAGYN 
       250        260        270        280        290        300 
LTGLFVGSEG TLGLITATTL RLHPAPEATV AATCAFPSVQ AAVDSTVHIL QAAVPVARIE 
       310        320        330        340        350        360 
FLDEVMMDAC NRYSKLNCLV APTLFLEFHG SQQALEEQLQ RTEEIVQQNG ASDFSWAKEA 
       370        380        390        400        410        420 
EERSRLWTAR HNAWYAALAT RPGCKGYSTD VCVPISRLPE IVVQTKEDLN ASGLTGSIVG 
       430        440        450        460        470        480 
HVGDGNFHCI LLVNPDDAEE LGRVKAFAEQ LGRRALALHG TCTGEHGIGM GKRQLLQEEV 
       490        500    
GAVGVETMRQ LKAVLDPQGL MNPGKVL



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q86WU2-0-unknown LMARLL... 0 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q86WU2-1-unknown MARLLR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt79476
    Q86WU2-1-unknown MARLLR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PGKVL 507 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...PGKVL 507 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt75094

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)