Q86WV6: Stimulator of interferon genes protein {ECO:0000303|PubMed:18724357}
General Information
| Protein names | - Stimulator of interferon genes protein {ECO:0000303|PubMed:18724357} - hSTING {ECO:0000303|PubMed:18724357, ECO:0000303|PubMed:23910378, ECO:0000303|PubMed:26669264} - Endoplasmic reticulum interferon stimulator {ECO:0000303|PubMed:19433799} - ERIS {ECO:0000303|PubMed:19433799} - Mediator of IRF3 activation {ECO:0000303|PubMed:18818105, ECO:0000303|PubMed:19285439} - hMITA {ECO:0000303|PubMed:18818105, ECO:0000303|PubMed:19285439} - Transmembrane protein 173 {ECO:0000305} |
|---|---|
| Gene names | TMEM173 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q86WV6 |
1
N-termini
2
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MPHSSLHPSI PCPRGHGAQK AALVLLSACL VTLWGLGEPP EHTLRYLVLH LASLQLGLLL
70 80 90 100 110 120
NGVCSLAEEL RHIHSRYRGS YWRTVRACLG CPLRRGALLL LSIYFYYSLP NAVGPPFTWM
130 140 150 160 170 180
LALLGLSQAL NILLGLKGLA PAEISAVCEK GNFNVAHGLA WSYYIGYLRL ILPELQARIR
190 200 210 220 230 240
TYNQHYNNLL RGAVSQRLYI LLPLDCGVPD NLSMADPNIR FLDKLPQQTG DHAGIKDRVY
250 260 270 280 290 300
SNSIYELLEN GQRAGTCVLE YATPLQTLFA MSQYSQAGFS REDRLEQAKL FCRTLEDILA
310 320 330 340 350 360
DAPESQNNCR LIAYQEPADD SSFSLSQEVL RHLRQEEKEE VTVGSLKTSA VPSTSTMSQE
370
PELLISGMEK PLPLRTDFS
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q86WV6-1-unknown | MPHSSL... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...ENGQRA | 253 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000427455 | |||
| ...RTDFS | 379 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|