Q86WZ0: HEAT repeat-containing protein 4

General Information

Protein names	- HEAT repeat-containing protein 4
Gene names	HEATR4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q86WZ0

2 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTRTQKGKTF LPHCFYQSLP PRLGWGMILN YSKLKGKEEC ASVSSVPMVF FSSQYRLHRK
        70         80         90        100        110        120
SQYLKMAAAN LTFSQEVVWQ RGLPSIPYSQ YSFDHLYNTN DIIHTPQIRK ARPQKPVSFK
       130        140        150        160        170        180
FLGSSSPLTG DTSLAVKTES SANPEKKLKK SKPASTVREA PRPLIHHPCM HPDMLGRPPS
       190        200        210        220        230        240
LDVNLEEREA WLLPPEKEAR AWEATVLEKL NERTARWIQS KRPRRPGASP NKWQSFLRQQ
       250        260        270        280        290        300
YDWSHIRDEL TSASDLELLK QLEAEETAEF EDQSVILPPQ EKKKPELLLP VYYRLPSYFQ
       310        320        330        340        350        360
QAETVEIMPG NKSTEDIHEK TSLSQPQTQS YFRQVTPRAG KFAYSTDNTF EQEIYFDEVQ
       370        380        390        400        410        420
IIHQIGAKRD QIVLENLNRY NKQLSKVFPE TPEKWSAQAI PEASYRPVQG ALRWTALPTP
       430        440        450        460        470        480
AKDMLLQVGE KDVPIKTRRL KKQAKSLQED VTWELVVLRR MLKEWKTAWA LIIEWHHETV
       490        500        510        520        530        540
ENLLQSLGDL HDDVRIKAIT TCATAALERP RIATSQRDSD KTIQDLPEVL LPALEAALCD
       550        560        570        580        590        600
KNAHVRMAAA ICQYAIQSHN PLARNIMQTA LLKGNSVDSW AAAQCLALEG TATYPVIKRI
       610        620        630        640        650        660
LHQLFTKKNE DTEEQSYILL SYLSEKTTLI HTMLAVELNS CQWKNRIVAC QAFSRISGNV
       670        680        690        700        710        720
CLDMKHKLIQ LMWNDWNKEV RRAAAQALGQ MSLGKEVHDI IRVKLGQGNS QERVEALYLI
       730        740        750        760        770        780
GELKLMTAKL LPSFLHCFSD DFTAVRRAAC LAAGALQIRD KMVLECLLNL MQRDPYWKIK
       790        800        810        820        830        840
AFAIRALGQI GQVSPELTDL LLWAIHYEES PGVRLEACRS ILALKLQGDR VRDTFLDVLL
       850        860        870        880        890        900
LENHDAVLKE MYQTMKILNL GNEGNQEMLQ EIKNRIKTLS QKDLLTHKIL KLEMVMGKVR
       910        920        930        940        950        960
EEAKRVYLKP KGEQGPLTLQ TLLQETFQDE MVLPRRPSEV CDTEAVIKPV KPRAPNPWLQ
       970        980        990       1000       1010       1020
SSVPGLTTRS KVRSSLVKDL RTSPEKRIAV GPFRSDYPAL YLGKFSERTF FSPIMSSPSG

KKGAHL

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q86WZ0-1-unknown	MTRTQK...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q86WZ0-48-unknown	MVFFSS...	48		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000453597

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SKLKGK	36	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456792
...KGKEEC	39	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000451367
...EREAWL	191	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000452407
...KGAHL	1026	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)