TopFIND 4.0

Q86X27: Ras-specific guanine nucleotide-releasing factor RalGPS2

General Information

Protein names
- Ras-specific guanine nucleotide-releasing factor RalGPS2
- Ral GEF with PH domain and SH3-binding motif 2
- RalA exchange factor RalGPS2
Gene names RALGPS2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q86X27

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDLMNGQASS VNIAATASEK SSSSESLSDK GSELKKSFDA VVFDVLKVTP EEYAGQITLM 
        70         80         90        100        110        120 
DVPVFKAIQP DELSSCGWNK KEKYSSAPNA VAFTRRFNHV SFWVVREILH AQTLKIRAEV 
       130        140        150        160        170        180 
LSHYIKTAKK LYELNNLHAL MAVVSGLQSA PIFRLTKTWA LLSRKDKTTF EKLEYVMSKE 
       190        200        210        220        230        240 
DNYKRLRDYI SSLKMTPCIP YLGIYLSDLT YIDSAYPSTG SILENEQRSN LMNNILRIIS 
       250        260        270        280        290        300 
DLQQSCEYDI PMLPHVQKYL NSVQYIEELQ KFVEDDNYKL SLKIEPGTST PRSAASREDL 
       310        320        330        340        350        360 
VGPEVGASPQ SGRKSVAAEG ALLPQTPPSP RNLIPHGHRK CHSLGYNFIH KMNTAEFKSA 
       370        380        390        400        410        420 
TFPNAGPRHL LDDSVMEPHA PSRGQAESST LSSGISIGSS DGSELSEETS WPAFERNRLY 
       430        440        450        460        470        480 
HSLGPVTRVA RNGYRSHMKA SSSAESEDLA VHLYPGAVTI QGVLRRKTLL KEGKKPTVAS 
       490        500        510        520        530        540 
WTKYWAALCG TQLFYYAAKS LKATERKHFK STSNKNVSVI GWMVMMADDP EHPDLFLLTD 
       550        560        570        580    
SEKGNSYKFQ AGNRMNAMLW FKHLSAACQS NKQQVPTNLM TFE

Isoforms

- Isoform 2 of Ras-specific guanine nucleotide-releasing factor RalGPS2 - Isoform 3 of Ras-specific guanine nucleotide-releasing factor RalGPS2

Sequence View

        10         20         30         40         50         60 
MDLMNGQASS VNIAATASEK SSSSESLSDK GSELKKSFDA VVFDVLKVTP EEYAGQITLM 
        70         80         90        100        110        120 
DVPVFKAIQP DELSSCGWNK KEKYSSAPNA VAFTRRFNHV SFWVVREILH AQTLKIRAEV 
       130        140        150        160        170        180 
LSHYIKTAKK LYELNNLHAL MAVVSGLQSA PIFRLTKTWA LLSRKDKTTF EKLEYVMSKE 
       190        200        210        220        230        240 
DNYKRLRDYI SSLKMTPCIP YLGIYLSDLT YIDSAYPSTG SILENEQRSN LMNNILRIIS 
       250        260        270        280        290        300 
DLQQSCEYDI PMLPHVQKYL NSVQYIEELQ KFVEDDNYKL SLKIEPGTST PRSAASREDL 
       310        320        330        340        350        360 
VGPEVGASPQ SGRKSVAAEG ALLPQTPPSP RNLIPHGHRK CHSLGYNFIH KMNTAEFKSA 
       370        380        390        400        410        420 
TFPNAGPRHL LDDSVMEPHA PSRGQAESST LSSGISIGSS DGSELSEETS WPAFERNRLY 
       430        440        450        460        470        480 
HSLGPVTRVA RNGYRSHMKA SSSAESEDLA VHLYPGAVTI QGVLRRKTLL KEGKKPTVAS 
       490        500        510        520        530        540 
WTKYWAALCG TQLFYYAAKS LKATERKHFK STSNKNVSVI GWMVMMADDP EHPDLFLLTD 
       550        560        570        580    
SEKGNSYKFQ AGNRMNAMLW FKHLSAACQS NKQQVPTNLM TFE         10         20         30         40         50         60 
MDLMNGQASS VNIAATASEK SSSSESLSDK GSELKKSFDA VVFDVLKVTP EEYAGQITLM 
        70         80         90        100        110        120 
DVPVFKAIQP DELSSCGWNK KEKYSSAPNA VAFTRRFNHV SFWVVREILH AQTLKIRAEV 
       130        140        150        160        170        180 
LSHYIKTAKK LYELNNLHAL MAVVSGLQSA PIFRLTKTWA LLSRKDKTTF EKLEYVMSKE 
       190        200        210        220        230        240 
DNYKRLRDYI SSLKMTPCIP YLGIYLSDLT YIDSAYPSTG SILENEQRSN LMNNILRIIS 
       250        260        270        280        290        300 
DLQQSCEYDI PMLPHVQKYL NSVQYIEELQ KFVEDDNYKL SLKIEPGTST PRSAASREDL 
       310        320        330        340        350        360 
VGPEVGASPQ SGRKSVAAEG ALLPQTPPSP RNLIPHGHRK CHSLGYNFIH KMNTAEFKSA 
       370        380        390        400        410        420 
TFPNAGPRHL LDDSVMEPHA PSRGQAESST LSSGISIGSS DGSELSEETS WPAFERNRLY 
       430        440        450        460        470        480 
HSLGPVTRVA RNGYRSHMKA SSSAESEDLA VHLYPGAVTI QGVLRRKTLL KEGKKPTVAS 
       490        500        510        520        530        540 
WTKYWAALCG TQLFYYAAKS LKATERKHFK STSNKNVSVI GWMVMMADDP EHPDLFLLTD 
       550        560        570        580    
SEKGNSYKFQ AGNRMNAMLW FKHLSAACQS NKQQVPTNLM TFE



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q86X27-1-unknown MDLMNG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q86X27-1-unknown MDLMNG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt87456
    Q86X27-1-unknown MDLMNG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt87457

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)