TopFIND 4.0

Q86XR7: TIR domain-containing adapter molecule 2

General Information

Protein names
- TIR domain-containing adapter molecule 2
- TICAM-2
- Putative NF-kappa-B-activating protein 502
- TRIF-related adapter molecule
- Toll-like receptor adaptor protein 3
- Toll/interleukin-1 receptor domain-containing protein
- MyD88-4
Gene names TICAM2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q86XR7

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGIGKSKINS CPLSLSWGKR HSVDTSPGYH ESDSKKSEDL SLCNVAEHSN TTEGPTGKQE 
        70         80         90        100        110        120 
GAQSVEEMFE EEAEEEVFLK FVILHAEDDT DEALRVQNLL QDDFGIKPGI IFAEMPCGRQ 
       130        140        150        160        170        180 
HLQNLDDAVN GSAWTILLLT ENFLRDTWCN FQFYTSLMNS VNRQHKYNSV IPMRPLNNPL 
       190        200        210        220        230    
PRERTPFALQ TINALEEESR GFPTQVERIF QESVYKTQQT IWKETRNMVQ RQFIA

Isoforms

- Isoform 2 of TIR domain-containing adapter molecule 2

Sequence View

        10         20         30         40         50         60 
MGIGKSKINS CPLSLSWGKR HSVDTSPGYH ESDSKKSEDL SLCNVAEHSN TTEGPTGKQE 
        70         80         90        100        110        120 
GAQSVEEMFE EEAEEEVFLK FVILHAEDDT DEALRVQNLL QDDFGIKPGI IFAEMPCGRQ 
       130        140        150        160        170        180 
HLQNLDDAVN GSAWTILLLT ENFLRDTWCN FQFYTSLMNS VNRQHKYNSV IPMRPLNNPL 
       190        200        210        220        230    
PRERTPFALQ TINALEEESR GFPTQVERIF QESVYKTQQT IWKETRNMVQ RQFIA



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Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q86XR7-2-unknown GIGKSK... 2 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RQFIA 235 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RQFIA 235 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt87320

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)