TopFIND 4.0

Q86YQ8: Copine-8 {ECO:0000305}

General Information

Protein names
- Copine-8 {ECO:0000305}
- Copine VIII {ECO:0000312|HGNC:HGNC:23498}
Gene names CPNE8
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q86YQ8

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDSRYNSTAG IGDLNQLSAA IPATRVEVSV SCRNLLDRDT FSKSDPICVL YVQGVGNKEW 
        70         80         90        100        110        120 
REFGRTEVID NTLNPDFVRK FILDYFFEER ENLRFDLYDV DSKSPNLSKH DFLGQVFCTL 
       130        140        150        160        170        180 
GEIVGSQGSR LEKPIVGIPG KKCGTIILTA EELNCCRDAV LMQFCANKLD KKDFFGKSDP 
       190        200        210        220        230        240 
FLVFYRSNED GSFTICHKTE VVKNTLNPVW QAFKISVRAL CNGDYDRTIK VEVYDWDRDG 
       250        260        270        280        290        300 
SHDFIGEFTT SYRELSRGQS QFNVYEVVNP KKKGKKKKYT NSGTVTLLSF LVETEVSFLD 
       310        320        330        340        350        360 
YIKGGTQINF TVAIDFTASN GNPAQPTSLH YMNPYQLNAY GMALKAVGEI VQDYDSDKMF 
       370        380        390        400        410        420 
PALGFGAKLP PDGRISHEFA LNGNPQNPYC DGIEGVMEAY YRSLKSVQLY GPTNFAPVIN 
       430        440        450        460        470        480 
HVARYASSVK DGSQYFVLLI VTDGVISDMA QTKESIVNAS KLPMSIIIVG VGPAEFDAMV 
       490        500        510        520        530        540 
ELDGDDVRVS SRGKYAERDI VQFVPFRDYI DRSGNHILSM ARLAKDVLAE IPEQFLSYMR 
       550        560    
ARGIKPSPAP PPYTPPTHVL QTQI

Isoforms

- Isoform 2 of Copine-8

Sequence View

        10         20         30         40         50         60 
MDSRYNSTAG IGDLNQLSAA IPATRVEVSV SCRNLLDRDT FSKSDPICVL YVQGVGNKEW 
        70         80         90        100        110        120 
REFGRTEVID NTLNPDFVRK FILDYFFEER ENLRFDLYDV DSKSPNLSKH DFLGQVFCTL 
       130        140        150        160        170        180 
GEIVGSQGSR LEKPIVGIPG KKCGTIILTA EELNCCRDAV LMQFCANKLD KKDFFGKSDP 
       190        200        210        220        230        240 
FLVFYRSNED GSFTICHKTE VVKNTLNPVW QAFKISVRAL CNGDYDRTIK VEVYDWDRDG 
       250        260        270        280        290        300 
SHDFIGEFTT SYRELSRGQS QFNVYEVVNP KKKGKKKKYT NSGTVTLLSF LVETEVSFLD 
       310        320        330        340        350        360 
YIKGGTQINF TVAIDFTASN GNPAQPTSLH YMNPYQLNAY GMALKAVGEI VQDYDSDKMF 
       370        380        390        400        410        420 
PALGFGAKLP PDGRISHEFA LNGNPQNPYC DGIEGVMEAY YRSLKSVQLY GPTNFAPVIN 
       430        440        450        460        470        480 
HVARYASSVK DGSQYFVLLI VTDGVISDMA QTKESIVNAS KLPMSIIIVG VGPAEFDAMV 
       490        500        510        520        530        540 
ELDGDDVRVS SRGKYAERDI VQFVPFRDYI DRSGNHILSM ARLAKDVLAE IPEQFLSYMR 
       550        560    
ARGIKPSPAP PPYTPPTHVL QTQI



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LQTQI 564 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)