TopFIND 4.0

Q8BH35: Complement component C8 beta chain

General Information

Protein names
- Complement component C8 beta chain
- Complement component 8 subunit beta
Gene names C8b
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8BH35

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKIGAQVWRA LAKSCLLCAT LGCLHFPGSR GGKPDFFETK AVNGSLVKSR PVRSVAEAPA 
        70         80         90        100        110        120 
PIDCELSTWS SWTACDPCQK KRYRHTYLLR PSQFYGELCD LSDKEVEDCV TNQPCRSQVR 
       130        140        150        160        170        180 
CEGFVCAQTG RCVNRRLLCN GDNDCGDQSD EANCRRIYKN CQREMEQYWA IDRLASGINL 
       190        200        210        220        230        240 
FTNTFEGPVL DHRYYAGGCS PHYILDTNFR KPYNVESYTP QTKCEYEFTL TEYESYSDFE 
       250        260        270        280        290        300 
RLVIEKKTHM FNFTSGFKVD GVMDLGIKVE SNEGKNYVTR TKRFAHTQSK FLHARSVLEV 
       310        320        330        340        350        360 
AHYKLKSRSL MLHYEFLQRV KSLPLEYSYG EYRDLLRDFG THFITEAVLG GIYEYTLIMN 
       370        380        390        400        410        420 
KDAMEQGDYT LSHVTACAGG SFGIGGMVYK VYVKVGVSAK KCSDIMKEIN ERNKRSTMVE 
       430        440        450        460        470        480 
DLVVLVRGGT SEDITALAYK ELPTPELMEA WGDAVKYNPA IIKIKAEPLY ELVTATDFAY 
       490        500        510        520        530        540 
SSTVKQNLKK ALEEFQSEVS SCRCAPCRGN GVPVLKGSRC ECICPGGFQG TACEVTYRKD 
       550        560        570        580    
IPIDGKWSCW SDWSACSGGH KTRHRQCNNP APHKGGSPCS GPASETLNC

Isoforms

- Isoform 2 of Complement component C8 beta chain

Sequence View

        10         20         30         40         50         60 
MKIGAQVWRA LAKSCLLCAT LGCLHFPGSR GGKPDFFETK AVNGSLVKSR PVRSVAEAPA 
        70         80         90        100        110        120 
PIDCELSTWS SWTACDPCQK KRYRHTYLLR PSQFYGELCD LSDKEVEDCV TNQPCRSQVR 
       130        140        150        160        170        180 
CEGFVCAQTG RCVNRRLLCN GDNDCGDQSD EANCRRIYKN CQREMEQYWA IDRLASGINL 
       190        200        210        220        230        240 
FTNTFEGPVL DHRYYAGGCS PHYILDTNFR KPYNVESYTP QTKCEYEFTL TEYESYSDFE 
       250        260        270        280        290        300 
RLVIEKKTHM FNFTSGFKVD GVMDLGIKVE SNEGKNYVTR TKRFAHTQSK FLHARSVLEV 
       310        320        330        340        350        360 
AHYKLKSRSL MLHYEFLQRV KSLPLEYSYG EYRDLLRDFG THFITEAVLG GIYEYTLIMN 
       370        380        390        400        410        420 
KDAMEQGDYT LSHVTACAGG SFGIGGMVYK VYVKVGVSAK KCSDIMKEIN ERNKRSTMVE 
       430        440        450        460        470        480 
DLVVLVRGGT SEDITALAYK ELPTPELMEA WGDAVKYNPA IIKIKAEPLY ELVTATDFAY 
       490        500        510        520        530        540 
SSTVKQNLKK ALEEFQSEVS SCRCAPCRGN GVPVLKGSRC ECICPGGFQG TACEVTYRKD 
       550        560        570        580    
IPIDGKWSCW SDWSACSGGH KTRHRQCNNP APHKGGSPCS GPASETLNC



Filter Information:


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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ETLNC 589 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ETLNC 589 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt66909

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)