TopFIND 4.0

Q8BIA4: F-box/WD repeat-containing protein 8

General Information

Protein names
- F-box/WD repeat-containing protein 8
- F-box and WD-40 domain-containing protein 8
Gene names Fbxw8
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8BIA4

4

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDDHNLEEFR RHWQEELAQS QALRRRRRLE AGERRSPRRP EAGARGEPAS GYLGLAQGLL 
        70         80         90        100        110        120 
EGAGRPPAPR PGRGGDRKDT SSRSRSPPDR DATEPEPLVD QLIRDLNELD DVPFFDVRLP 
       130        140        150        160        170        180 
YELAINIFQY LNRRELGLCA QVSKTWKVIA EDEVLWYRLC RQEGHLPHSR FSDYTCWKLI 
       190        200        210        220        230        240 
LQECLAKEHT LRANWKNRKG AVSELEHVPD AVLCDVRSHD GVVIAGYTSG DVRVWDTRTW 
       250        260        270        280        290        300 
DYVAPFLESE SEEEDPGMQP YVSFVRINSS LAVAAYEDGI LNIWDLRTGR FPIFRFEHDA 
       310        320        330        340        350        360 
RIQALALSQE KPIVATASAF DVVMLYPNEE GHWHVASEFE VQKLVDYLEI VPNTGRYPVA 
       370        380        390        400        410        420 
IATAGDLVYL LKADDSARTL HYVYGQPATC LDVSASQVAF GVKSLGWVYE GNKILVYSLE 
       430        440        450        460        470        480 
AERCLSKLGN ALGDFTCVNI RDSPPNLMVS GNMDRRVRIH DLRSDKIALS LSAHQLGVSA 
       490        500        510        520        530        540 
VQMDDWKVVS GGEEGLVSVW DYRMNQKLWE VHSRHPVRYL SFNSHSLITA NVPYEKVLRN 
       550        560        570        580        590    
SDLDNFACHR RHRGLIHAYE FAVDQLAFQS PLPVCRLPRD IMAGYSYDLA LSFPHDSI

Isoforms

- Isoform 2 of F-box/WD repeat-containing protein 8

Sequence View

        10         20         30         40         50         60 
MDDHNLEEFR RHWQEELAQS QALRRRRRLE AGERRSPRRP EAGARGEPAS GYLGLAQGLL 
        70         80         90        100        110        120 
EGAGRPPAPR PGRGGDRKDT SSRSRSPPDR DATEPEPLVD QLIRDLNELD DVPFFDVRLP 
       130        140        150        160        170        180 
YELAINIFQY LNRRELGLCA QVSKTWKVIA EDEVLWYRLC RQEGHLPHSR FSDYTCWKLI 
       190        200        210        220        230        240 
LQECLAKEHT LRANWKNRKG AVSELEHVPD AVLCDVRSHD GVVIAGYTSG DVRVWDTRTW 
       250        260        270        280        290        300 
DYVAPFLESE SEEEDPGMQP YVSFVRINSS LAVAAYEDGI LNIWDLRTGR FPIFRFEHDA 
       310        320        330        340        350        360 
RIQALALSQE KPIVATASAF DVVMLYPNEE GHWHVASEFE VQKLVDYLEI VPNTGRYPVA 
       370        380        390        400        410        420 
IATAGDLVYL LKADDSARTL HYVYGQPATC LDVSASQVAF GVKSLGWVYE GNKILVYSLE 
       430        440        450        460        470        480 
AERCLSKLGN ALGDFTCVNI RDSPPNLMVS GNMDRRVRIH DLRSDKIALS LSAHQLGVSA 
       490        500        510        520        530        540 
VQMDDWKVVS GGEEGLVSVW DYRMNQKLWE VHSRHPVRYL SFNSHSLITA NVPYEKVLRN 
       550        560        570        580        590    
SDLDNFACHR RHRGLIHAYE FAVDQLAFQS PLPVCRLPRD IMAGYSYDLA LSFPHDSI



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Evidence Codes:


Methodology:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...NMDRRV 456 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt70568
    ...PHDSI 598 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)