Q8BIZ1: Ankyrin repeat and sterile alpha motif domain-containing protein 1B

General Information

Protein names	- Ankyrin repeat and sterile alpha motif domain-containing protein 1B - Amyloid-beta protein intracellular domain-associated protein 1 - AIDA-1 - E2A-PBX1-associated protein - EB-1
Gene names	Anks1b
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8BIZ1

5 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Ankyrin repeat and sterile alpha motif domain-containing protein 1B - Isoform 3 of Ankyrin repeat and sterile alpha motif domain-containing protein 1B - Isoform 4 of Ankyrin repeat and sterile alpha motif domain-containing protein 1B - Isoform 5 of Ankyrin repeat and sterile alpha motif domain-containing protein 1B

Sequence View

        10         20         30         40         50         60
MGKDQELLEA ARTGNVALVE KLLSGRKGGI LGGGSGPLPL SNLLSIWRGP NVNCTDSSGY
        70         80         90        100        110        120
TALHHAALNG HKDIVLKLLQ YEASTNVADN KGYFPIHLAA WKGDVEIVKI LIHHGPSHSR
       130        140        150        160        170        180
VNEQNNENET ALHCAAQYGH SEVVAVLLEE LTDPTIRNSK LETPLDLAAL YGRLRVVKMI
       190        200        210        220        230        240
ISAHPNLMSC NTRKHTPLHL AARNGHKAVV QVLLEAGMDV SCQTEKGSAL HEAALFGKVD
       250        260        270        280        290        300
VVRVLLETGI DANIKDSLGR TVLDILKEHP SQKSLQIATL LQDYLEGAGR SAAVLEEHAQ
       310        320        330        340        350        360
EDTAQETHLS SPAESPQKTK SETVTGELSK LLDEIKLCQE KDYSFEDLCH TISDHYLDNL
       370        380        390        400        410        420
SKISEEELGK NGSQSVRTSS TINLSPGEVE DEEEDPNSCG PTGLWEALTP CNGCRNLGFP
       430        440        450        460        470        480
MLAQESYPKK RNFPMEMEPS ASLDTFPSEN ENFLCELVDT AVTKKPCSLE IARAPSPRTD
       490        500        510        520        530        540
NASEVAITAP GTSHHRNSST GPTPDCSPPS PDTALKNIVK VIRPQPKQRT SIVSSLDFQR
       550        560        570        580        590        600
MNHNQEYFEI STSTGCTSFT SSPAASPPTS SVETTEVKNE GAEHADDLSQ QEDDEPPKEY
       610        620        630        640        650        660
DAGQFAGLLH GSSPACESPE NPFHLYGKRN TCEDGPDEAS LANSPLPFKQ TPIENNPEPS
       670        680        690        700        710        720
VKKVKPKVVS RTIFHKRNHQ LENHTIVGTR MSRSGSRNGD QWGVNPGGFV ERACTLGRIR
       730        740        750        760        770        780
SLPKALIDMH LSKNVSKSDS DLIAYPSKDK ARVNWSKSST AERSSKDNSE RTPSFTSEWE
       790        800        810        820        830        840
EIDKIMNSID VGINSELEGM NGETTRPRCP VQTVGQWLES IGLPQYENHL MANGFDSVQF
       850        860        870        880        890        900
MGSNVMEDQD LLEIGILNSG HRQRILQAIQ LLPKMRPIGH DGYHPTSVAE WLDSIELGDY
       910        920        930        940        950        960
TKAFLINGYT SMDLLKKIWE LELINVLKIS LIGHRKRILA SLGDRLHDDP PQKPPRSITL
       970        980        990       1000       1010       1020
REPSGNHTPP QLSPSLSQST YTTGGSLDVP HIIMQGDARR RRNENYFDDI PRSKLERQMA
      1030       1040       1050       1060       1070       1080
QTGDWGEPSI TLRPPNEATA STPVQYWQHH PEKLIFQSCD YKAFYLGSML IKELRGTEST
      1090       1100       1110       1120       1130       1140
QDACAKMRAN CRKSTEQMKK VPTIILSVSY KGVKFIDAAN KNIIAEHEIR NISCAAQDPE
      1150       1160       1170       1180       1190       1200
DLSTFAYITK DLKSNHHYCH VFTAFDVNLA YEIILTLGQA FEVAYQLALQ ARKGGHSSTL
      1210       1220       1230       1240       1250
PESFENKPSK PIPKPRVSIR KSVQIDPSEQ KTLANLPWIV EPGQEAKRGI NTKYETTIF         10         20         30         40         50         60
MGKDQELLEA ARTGNVALVE KLLSGRKGGI LGGGSGPLPL SNLLSIWRGP NVNCTDSSGY
        70         80         90        100        110        120
TALHHAALNG HKDIVLKLLQ YEASTNVADN KGYFPIHLAA WKGDVEIVKI LIHHGPSHSR
       130        140        150        160        170        180
VNEQNNENET ALHCAAQYGH SEVVAVLLEE LTDPTIRNSK LETPLDLAAL YGRLRVVKMI
       190        200        210        220        230        240
ISAHPNLMSC NTRKHTPLHL AARNGHKAVV QVLLEAGMDV SCQTEKGSAL HEAALFGKVD
       250        260        270        280        290        300
VVRVLLETGI DANIKDSLGR TVLDILKEHP SQKSLQIATL LQDYLEGAGR SAAVLEEHAQ
       310        320        330        340        350        360
EDTAQETHLS SPAESPQKTK SETVTGELSK LLDEIKLCQE KDYSFEDLCH TISDHYLDNL
       370        380        390        400        410        420
SKISEEELGK NGSQSVRTSS TINLSPGEVE DEEEDPNSCG PTGLWEALTP CNGCRNLGFP
       430        440        450        460        470        480
MLAQESYPKK RNFPMEMEPS ASLDTFPSEN ENFLCELVDT AVTKKPCSLE IARAPSPRTD
       490        500        510        520        530        540
NASEVAITAP GTSHHRNSST GPTPDCSPPS PDTALKNIVK VIRPQPKQRT SIVSSLDFQR
       550        560        570        580        590        600
MNHNQEYFEI STSTGCTSFT SSPAASPPTS SVETTEVKNE GAEHADDLSQ QEDDEPPKEY
       610        620        630        640        650        660
DAGQFAGLLH GSSPACESPE NPFHLYGKRN TCEDGPDEAS LANSPLPFKQ TPIENNPEPS
       670        680        690        700        710        720
VKKVKPKVVS RTIFHKRNHQ LENHTIVGTR MSRSGSRNGD QWGVNPGGFV ERACTLGRIR
       730        740        750        760        770        780
SLPKALIDMH LSKNVSKSDS DLIAYPSKDK ARVNWSKSST AERSSKDNSE RTPSFTSEWE
       790        800        810        820        830        840
EIDKIMNSID VGINSELEGM NGETTRPRCP VQTVGQWLES IGLPQYENHL MANGFDSVQF
       850        860        870        880        890        900
MGSNVMEDQD LLEIGILNSG HRQRILQAIQ LLPKMRPIGH DGYHPTSVAE WLDSIELGDY
       910        920        930        940        950        960
TKAFLINGYT SMDLLKKIWE LELINVLKIS LIGHRKRILA SLGDRLHDDP PQKPPRSITL
       970        980        990       1000       1010       1020
REPSGNHTPP QLSPSLSQST YTTGGSLDVP HIIMQGDARR RRNENYFDDI PRSKLERQMA
      1030       1040       1050       1060       1070       1080
QTGDWGEPSI TLRPPNEATA STPVQYWQHH PEKLIFQSCD YKAFYLGSML IKELRGTEST
      1090       1100       1110       1120       1130       1140
QDACAKMRAN CRKSTEQMKK VPTIILSVSY KGVKFIDAAN KNIIAEHEIR NISCAAQDPE
      1150       1160       1170       1180       1190       1200
DLSTFAYITK DLKSNHHYCH VFTAFDVNLA YEIILTLGQA FEVAYQLALQ ARKGGHSSTL
      1210       1220       1230       1240       1250
PESFENKPSK PIPKPRVSIR KSVQIDPSEQ KTLANLPWIV EPGQEAKRGI NTKYETTIF         10         20         30         40         50         60
MGKDQELLEA ARTGNVALVE KLLSGRKGGI LGGGSGPLPL SNLLSIWRGP NVNCTDSSGY
        70         80         90        100        110        120
TALHHAALNG HKDIVLKLLQ YEASTNVADN KGYFPIHLAA WKGDVEIVKI LIHHGPSHSR
       130        140        150        160        170        180
VNEQNNENET ALHCAAQYGH SEVVAVLLEE LTDPTIRNSK LETPLDLAAL YGRLRVVKMI
       190        200        210        220        230        240
ISAHPNLMSC NTRKHTPLHL AARNGHKAVV QVLLEAGMDV SCQTEKGSAL HEAALFGKVD
       250        260        270        280        290        300
VVRVLLETGI DANIKDSLGR TVLDILKEHP SQKSLQIATL LQDYLEGAGR SAAVLEEHAQ
       310        320        330        340        350        360
EDTAQETHLS SPAESPQKTK SETVTGELSK LLDEIKLCQE KDYSFEDLCH TISDHYLDNL
       370        380        390        400        410        420
SKISEEELGK NGSQSVRTSS TINLSPGEVE DEEEDPNSCG PTGLWEALTP CNGCRNLGFP
       430        440        450        460        470        480
MLAQESYPKK RNFPMEMEPS ASLDTFPSEN ENFLCELVDT AVTKKPCSLE IARAPSPRTD
       490        500        510        520        530        540
NASEVAITAP GTSHHRNSST GPTPDCSPPS PDTALKNIVK VIRPQPKQRT SIVSSLDFQR
       550        560        570        580        590        600
MNHNQEYFEI STSTGCTSFT SSPAASPPTS SVETTEVKNE GAEHADDLSQ QEDDEPPKEY
       610        620        630        640        650        660
DAGQFAGLLH GSSPACESPE NPFHLYGKRN TCEDGPDEAS LANSPLPFKQ TPIENNPEPS
       670        680        690        700        710        720
VKKVKPKVVS RTIFHKRNHQ LENHTIVGTR MSRSGSRNGD QWGVNPGGFV ERACTLGRIR
       730        740        750        760        770        780
SLPKALIDMH LSKNVSKSDS DLIAYPSKDK ARVNWSKSST AERSSKDNSE RTPSFTSEWE
       790        800        810        820        830        840
EIDKIMNSID VGINSELEGM NGETTRPRCP VQTVGQWLES IGLPQYENHL MANGFDSVQF
       850        860        870        880        890        900
MGSNVMEDQD LLEIGILNSG HRQRILQAIQ LLPKMRPIGH DGYHPTSVAE WLDSIELGDY
       910        920        930        940        950        960
TKAFLINGYT SMDLLKKIWE LELINVLKIS LIGHRKRILA SLGDRLHDDP PQKPPRSITL
       970        980        990       1000       1010       1020
REPSGNHTPP QLSPSLSQST YTTGGSLDVP HIIMQGDARR RRNENYFDDI PRSKLERQMA
      1030       1040       1050       1060       1070       1080
QTGDWGEPSI TLRPPNEATA STPVQYWQHH PEKLIFQSCD YKAFYLGSML IKELRGTEST
      1090       1100       1110       1120       1130       1140
QDACAKMRAN CRKSTEQMKK VPTIILSVSY KGVKFIDAAN KNIIAEHEIR NISCAAQDPE
      1150       1160       1170       1180       1190       1200
DLSTFAYITK DLKSNHHYCH VFTAFDVNLA YEIILTLGQA FEVAYQLALQ ARKGGHSSTL
      1210       1220       1230       1240       1250
PESFENKPSK PIPKPRVSIR KSVQIDPSEQ KTLANLPWIV EPGQEAKRGI NTKYETTIF         10         20         30         40         50         60
MGKDQELLEA ARTGNVALVE KLLSGRKGGI LGGGSGPLPL SNLLSIWRGP NVNCTDSSGY
        70         80         90        100        110        120
TALHHAALNG HKDIVLKLLQ YEASTNVADN KGYFPIHLAA WKGDVEIVKI LIHHGPSHSR
       130        140        150        160        170        180
VNEQNNENET ALHCAAQYGH SEVVAVLLEE LTDPTIRNSK LETPLDLAAL YGRLRVVKMI
       190        200        210        220        230        240
ISAHPNLMSC NTRKHTPLHL AARNGHKAVV QVLLEAGMDV SCQTEKGSAL HEAALFGKVD
       250        260        270        280        290        300
VVRVLLETGI DANIKDSLGR TVLDILKEHP SQKSLQIATL LQDYLEGAGR SAAVLEEHAQ
       310        320        330        340        350        360
EDTAQETHLS SPAESPQKTK SETVTGELSK LLDEIKLCQE KDYSFEDLCH TISDHYLDNL
       370        380        390        400        410        420
SKISEEELGK NGSQSVRTSS TINLSPGEVE DEEEDPNSCG PTGLWEALTP CNGCRNLGFP
       430        440        450        460        470        480
MLAQESYPKK RNFPMEMEPS ASLDTFPSEN ENFLCELVDT AVTKKPCSLE IARAPSPRTD
       490        500        510        520        530        540
NASEVAITAP GTSHHRNSST GPTPDCSPPS PDTALKNIVK VIRPQPKQRT SIVSSLDFQR
       550        560        570        580        590        600
MNHNQEYFEI STSTGCTSFT SSPAASPPTS SVETTEVKNE GAEHADDLSQ QEDDEPPKEY
       610        620        630        640        650        660
DAGQFAGLLH GSSPACESPE NPFHLYGKRN TCEDGPDEAS LANSPLPFKQ TPIENNPEPS
       670        680        690        700        710        720
VKKVKPKVVS RTIFHKRNHQ LENHTIVGTR MSRSGSRNGD QWGVNPGGFV ERACTLGRIR
       730        740        750        760        770        780
SLPKALIDMH LSKNVSKSDS DLIAYPSKDK ARVNWSKSST AERSSKDNSE RTPSFTSEWE
       790        800        810        820        830        840
EIDKIMNSID VGINSELEGM NGETTRPRCP VQTVGQWLES IGLPQYENHL MANGFDSVQF
       850        860        870        880        890        900
MGSNVMEDQD LLEIGILNSG HRQRILQAIQ LLPKMRPIGH DGYHPTSVAE WLDSIELGDY
       910        920        930        940        950        960
TKAFLINGYT SMDLLKKIWE LELINVLKIS LIGHRKRILA SLGDRLHDDP PQKPPRSITL
       970        980        990       1000       1010       1020
REPSGNHTPP QLSPSLSQST YTTGGSLDVP HIIMQGDARR RRNENYFDDI PRSKLERQMA
      1030       1040       1050       1060       1070       1080
QTGDWGEPSI TLRPPNEATA STPVQYWQHH PEKLIFQSCD YKAFYLGSML IKELRGTEST
      1090       1100       1110       1120       1130       1140
QDACAKMRAN CRKSTEQMKK VPTIILSVSY KGVKFIDAAN KNIIAEHEIR NISCAAQDPE
      1150       1160       1170       1180       1190       1200
DLSTFAYITK DLKSNHHYCH VFTAFDVNLA YEIILTLGQA FEVAYQLALQ ARKGGHSSTL
      1210       1220       1230       1240       1250
PESFENKPSK PIPKPRVSIR KSVQIDPSEQ KTLANLPWIV EPGQEAKRGI NTKYETTIF

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8BIZ1-1-unknown	MGKDQE...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8BIZ1-831-unknown	MANGFD...	831	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt67089
Q8BIZ1-831-unknown	MANGFD...	831	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000138234
Q8BIZ1-831-unknown	MANGFD...	831	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000138720
Q8BIZ1-831-unknown	MANGFD...	831	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000138650
Q8BIZ1-831-unknown	MANGFD...	831	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96810
Q8BIZ1-831-unknown	MANGFD...	831	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96811
Q8BIZ1-926-unknown	VLKISL...	926	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000136123
Q8BIZ1-926-unknown	VLKISL...	926	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt133141
Q8BIZ1-926-unknown	VLKISL...	926	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt133140
Q8BIZ1-926-unknown	VLKISL...	926	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt133142
Q8BIZ1-994-unknown	MQGDAR...	994	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt67091
Q8BIZ1-994-unknown	MQGDAR...	994	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000138610
Q8BIZ1-994-unknown	MQGDAR...	994	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000136146
Q8BIZ1-994-unknown	MQGDAR...	994	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000136410
Q8BIZ1-994-unknown	MQGDAR...	994	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000096967
Q8BIZ1-994-unknown	MQGDAR...	994	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96959
Q8BIZ1-1069-unknown	MLIKEL...	1069	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000138701
Q8BIZ1-1069-unknown	MLIKEL...	1069	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000138398
Q8BIZ1-1069-unknown	MLIKEL...	1069	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt133138
Q8BIZ1-1069-unknown	MLIKEL...	1069	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt133135
Q8BIZ1-1069-unknown	MLIKEL...	1069	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt133136
Q8BIZ1-1069-unknown	MLIKEL...	1069	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt133137

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EDDEPP	596	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000138209
...GDWGEP	1027	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000138480
...GDWGEP	1027	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115791
...GDWGEP	1027	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115790
...ETTIF	1259	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ETTIF	1259	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62709
...ETTIF	1259	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62706
...ETTIF	1259	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62708

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)