TopFIND 4.0

Q8BJ37: Tyrosyl-DNA phosphodiesterase 1

General Information

Protein names
- Tyrosyl-DNA phosphodiesterase 1
- Tyr-DNA phosphodiesterase 1
- 3.1.4.- {ECO:0000250|UniProtKB:Q9NUW8}
- Protein expressed in male leptotene and zygotene spermatocytes 501
- MLZ-501
Gene names Tdp1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8BJ37

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSQESSYGKW TISSSDESED EKPKPDKPSA SSHPQAGQGV SKELIYTCSE ARKVAHKRQI 
        70         80         90        100        110        120 
SPVKFNDADS VLPHKKQKSD SPEGLGWCLS SSDDDQQPDV TQQEQPKRVL PQEKKHVSSP 
       130        140        150        160        170        180 
DVTTAQKVVD RSPPASLRPQ RADDEYETSG EGQDIWDMLD KGNPFQFYLT RVSGIKAKYN 
       190        200        210        220        230        240 
SKALHIKDIL SPLFGTLVSS AQFNYCFDVD WLIKQYPPEF RKNPILLVHG DKREAKADLH 
       250        260        270        280        290        300 
AQAKPYANIS LCQAKLDIAF GTHHTKMMLL LYEEGLRVVI HTSNLIREDW HQKTQGIWLS 
       310        320        330        340        350        360 
PLYPRIDQGS HTAGESSTRF KADLTSYLTA YNAPPLQEWI DIIQEHDLSE TNVYLIGSTP 
       370        380        390        400        410        420 
GRFQGSHRDN WGHFRLRKLL QAHAPSTPKG ECWPIVGQFS SIGSLGPDES KWLCSEFKDS 
       430        440        450        460        470        480 
LLALREEGRP PGKSAVPLHL IYPSVENVRT SLEGYPAGGS LPYSIQTAEK QRWLHSYFHK 
       490        500        510        520        530        540 
WSAETSGRSN AMPHIKTYMR PSPDFSKLAW FLVTSANLSK AAWGALEKNG TQLMIRSYEL 
       550        560        570        580        590        600 
GVLFLPSAFG LDTFKVKQKF FSSSCEPTAS FPVPYDLPPE LYRSKDRPWI WNIPYVKAPD 
   
THGNMWVPS

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8BJ37-1-unknown MSQESS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...MWVPS 609 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)