TopFIND 4.0

Q8BJM7: S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase

General Information

Protein names
- S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase
- 4.1.3.44
- Radical S-adenosyl methionine and flavodoxin domain-containing protein 1
- tRNA wybutosine-synthesizing protein 1 homolog
- tRNA-yW-synthesizing protein
Gene names Tyw1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8BJM7

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGPLDVWDLS PLLSLWMNRF YIYMGCALGL TLCICVQIIK KQVTRSQEKR VPGAPDSSLS 
        70         80         90        100        110        120 
PQKKQTHVSG VKIFYGSQTG TAKGFAVVLA KAVTSLDLPV AIINLKEYDP DDSLIGEITS 
       130        140        150        160        170        180 
KTVCAFLVAT YTDGCPTESA EWFCKWLEES ANDFRFGKTY LKGLRYAVFG LGDSAYRSHF 
       190        200        210        220        230        240 
NKVSTNVDKW LWMLGAQRVL TRGEGDCNAV QSKHGSIEAD FTAWKTKFIS RLQALQRGEK 
       250        260        270        280        290        300 
KACGGNCKRG KCESAQHGPG EARPHPQGEL HPGDAEEEEP CESSSEDELG TQDYQSLTSV 
       310        320        330        340        350        360 
VDVEDLGNIM NPVKREKREK SHQDGKAAMQ RNPEKTEDGE GRAMITPALR EALTKQGYQL 
       370        380        390        400        410        420 
IGSHSGVKLC RWTKSMLRGR GGCYKHTFYG IESHRCMEAT PSLACANKCV FCWRHHTNPV 
       430        440        450        460        470        480 
GTEWRWKMDQ PELILKEAIE NHQNMIKQFK GVPGLKAERF EEGMEVKHCA LSLVGEPIMY 
       490        500        510        520        530        540 
PEINRLLKLL HQHGISSFLV TNAQFPEEIR KLTPVTQLYV SVDASTRDGL KKIDRPLFKD 
       550        560        570        580        590        600 
FWQRFLDSLK ALSAKQQRTV YRLTLVKCWN VDELQAYAEL VSLGNPDFIE VKGVTYCGES 
       610        620        630        640        650        660 
AASSLTMANV PWHEEVVRFV RELVDLLPDY EVACEHEHSN CLLIGHKKFK IDGEWWTWIN 
       670        680        690        700        710        720 
YSRFQELVLQ YEESGGSKTF SSRDYMARTP QWALFGARER GFDPKDTRYQ RKNKTKDISG 
   
C

Isoforms

- Isoform 2 of S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase - Isoform 2 of S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

Sequence View

        10         20         30         40         50         60 
MGPLDVWDLS PLLSLWMNRF YIYMGCALGL TLCICVQIIK KQVTRSQEKR VPGAPDSSLS 
        70         80         90        100        110        120 
PQKKQTHVSG VKIFYGSQTG TAKGFAVVLA KAVTSLDLPV AIINLKEYDP DDSLIGEITS 
       130        140        150        160        170        180 
KTVCAFLVAT YTDGCPTESA EWFCKWLEES ANDFRFGKTY LKGLRYAVFG LGDSAYRSHF 
       190        200        210        220        230        240 
NKVSTNVDKW LWMLGAQRVL TRGEGDCNAV QSKHGSIEAD FTAWKTKFIS RLQALQRGEK 
       250        260        270        280        290        300 
KACGGNCKRG KCESAQHGPG EARPHPQGEL HPGDAEEEEP CESSSEDELG TQDYQSLTSV 
       310        320        330        340        350        360 
VDVEDLGNIM NPVKREKREK SHQDGKAAMQ RNPEKTEDGE GRAMITPALR EALTKQGYQL 
       370        380        390        400        410        420 
IGSHSGVKLC RWTKSMLRGR GGCYKHTFYG IESHRCMEAT PSLACANKCV FCWRHHTNPV 
       430        440        450        460        470        480 
GTEWRWKMDQ PELILKEAIE NHQNMIKQFK GVPGLKAERF EEGMEVKHCA LSLVGEPIMY 
       490        500        510        520        530        540 
PEINRLLKLL HQHGISSFLV TNAQFPEEIR KLTPVTQLYV SVDASTRDGL KKIDRPLFKD 
       550        560        570        580        590        600 
FWQRFLDSLK ALSAKQQRTV YRLTLVKCWN VDELQAYAEL VSLGNPDFIE VKGVTYCGES 
       610        620        630        640        650        660 
AASSLTMANV PWHEEVVRFV RELVDLLPDY EVACEHEHSN CLLIGHKKFK IDGEWWTWIN 
       670        680        690        700        710        720 
YSRFQELVLQ YEESGGSKTF SSRDYMARTP QWALFGARER GFDPKDTRYQ RKNKTKDISG 
   
C         10         20         30         40         50         60 
MGPLDVWDLS PLLSLWMNRF YIYMGCALGL TLCICVQIIK KQVTRSQEKR VPGAPDSSLS 
        70         80         90        100        110        120 
PQKKQTHVSG VKIFYGSQTG TAKGFAVVLA KAVTSLDLPV AIINLKEYDP DDSLIGEITS 
       130        140        150        160        170        180 
KTVCAFLVAT YTDGCPTESA EWFCKWLEES ANDFRFGKTY LKGLRYAVFG LGDSAYRSHF 
       190        200        210        220        230        240 
NKVSTNVDKW LWMLGAQRVL TRGEGDCNAV QSKHGSIEAD FTAWKTKFIS RLQALQRGEK 
       250        260        270        280        290        300 
KACGGNCKRG KCESAQHGPG EARPHPQGEL HPGDAEEEEP CESSSEDELG TQDYQSLTSV 
       310        320        330        340        350        360 
VDVEDLGNIM NPVKREKREK SHQDGKAAMQ RNPEKTEDGE GRAMITPALR EALTKQGYQL 
       370        380        390        400        410        420 
IGSHSGVKLC RWTKSMLRGR GGCYKHTFYG IESHRCMEAT PSLACANKCV FCWRHHTNPV 
       430        440        450        460        470        480 
GTEWRWKMDQ PELILKEAIE NHQNMIKQFK GVPGLKAERF EEGMEVKHCA LSLVGEPIMY 
       490        500        510        520        530        540 
PEINRLLKLL HQHGISSFLV TNAQFPEEIR KLTPVTQLYV SVDASTRDGL KKIDRPLFKD 
       550        560        570        580        590        600 
FWQRFLDSLK ALSAKQQRTV YRLTLVKCWN VDELQAYAEL VSLGNPDFIE VKGVTYCGES 
       610        620        630        640        650        660 
AASSLTMANV PWHEEVVRFV RELVDLLPDY EVACEHEHSN CLLIGHKKFK IDGEWWTWIN 
       670        680        690        700        710        720 
YSRFQELVLQ YEESGGSKTF SSRDYMARTP QWALFGARER GFDPKDTRYQ RKNKTKDISG 
   
C



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)