TopFIND 4.0

Q8BJW6: Eukaryotic translation initiation factor 2A

General Information

Protein names
- Eukaryotic translation initiation factor 2A
- eIF-2A
- Eukaryotic translation initiation factor 2A, N-terminally processed
Gene names Eif2a
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8BJW6

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAPSTPLLTV RGSEGLYMVN GPPHFTESTV LPRESGRNCK VYTFSKDGTL FAWSNGEKVN 
        70         80         90        100        110        120 
IINVANKGLL HSFDLPKAVC LEFSPNNTVL ATWQPYTTSK DGTAGTPNLQ LYDMKTGACL 
       130        140        150        160        170        180 
KSFIQKKMQN WCPSWSDDEI ICARNVNNEV HFFENNNFNT IANKLHLQKV NDFNLSPGTQ 
       190        200        210        220        230        240 
PYKVAVYVPG SKGAPSFVRL YQYPNFAGPQ AALANKSFFK ADKVTMLWNK KATAVLVIAS 
       250        260        270        280        290        300 
TEVDKTGASY YGEQTLHYIA TNGESAVVQL PKNGPIYDVV WNSSSTEFCA VYGFMPAKAT 
       310        320        330        340        350        360 
VFNLKCDPVF DFGTGPRNAA FYSPHGHILV LAGFGNLRGQ MEVWDVKNYK LISKPVASDS 
       370        380        390        400        410        420 
TYFAWCPDGE HILTATCAPR LRVNNGYKIW HYTGSLLHKY DVPSNGELWQ VSWQPFLDGI 
       430        440        450        460        470        480 
FPAKTIKYQA VPSEVPSEEP KVATAYRPPA LRNKPVTNSK LHEEEPPQNM KPHPGSDKPL 
       490        500        510        520        530        540 
SKTALKNQRK HEAKKAAKQE ARSDAAPTPV PQSAPRNTVT QSASGDPEVD KKIKNLKKKL 
       550        560        570        580    
KAIEQLKEQA AAGKQLEKNQ LEKIQKETAL LQELEDLELG V

Isoforms

- Isoform 2 of Eukaryotic translation initiation factor 2A

Sequence View

        10         20         30         40         50         60 
MAPSTPLLTV RGSEGLYMVN GPPHFTESTV LPRESGRNCK VYTFSKDGTL FAWSNGEKVN 
        70         80         90        100        110        120 
IINVANKGLL HSFDLPKAVC LEFSPNNTVL ATWQPYTTSK DGTAGTPNLQ LYDMKTGACL 
       130        140        150        160        170        180 
KSFIQKKMQN WCPSWSDDEI ICARNVNNEV HFFENNNFNT IANKLHLQKV NDFNLSPGTQ 
       190        200        210        220        230        240 
PYKVAVYVPG SKGAPSFVRL YQYPNFAGPQ AALANKSFFK ADKVTMLWNK KATAVLVIAS 
       250        260        270        280        290        300 
TEVDKTGASY YGEQTLHYIA TNGESAVVQL PKNGPIYDVV WNSSSTEFCA VYGFMPAKAT 
       310        320        330        340        350        360 
VFNLKCDPVF DFGTGPRNAA FYSPHGHILV LAGFGNLRGQ MEVWDVKNYK LISKPVASDS 
       370        380        390        400        410        420 
TYFAWCPDGE HILTATCAPR LRVNNGYKIW HYTGSLLHKY DVPSNGELWQ VSWQPFLDGI 
       430        440        450        460        470        480 
FPAKTIKYQA VPSEVPSEEP KVATAYRPPA LRNKPVTNSK LHEEEPPQNM KPHPGSDKPL 
       490        500        510        520        530        540 
SKTALKNQRK HEAKKAAKQE ARSDAAPTPV PQSAPRNTVT QSASGDPEVD KKIKNLKKKL 
       550        560        570        580    
KAIEQLKEQA AAGKQLEKNQ LEKIQKETAL LQELEDLELG V



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LELGV 581 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LELGV 581 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt69382

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)