TopFIND 4.0

Q8BK03: Mitoguardin 2 {ECO:0000250|UniProtKB:Q7L4E1}

General Information

Protein names
- Mitoguardin 2 {ECO:0000250|UniProtKB:Q7L4E1}
- Protein FAM73B
Gene names Fam73b
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8BK03

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAFRRTEGMS MIQALAMTVA EIPVFLYTTF GQSAFSQLRL TPGLRKVLFA TALGTVALAL 
        70         80         90        100        110        120 
AAHQLKRRRR KKKQVGPEMG GEQLGTVPMP ILMARKVPSV KKGCSSRRVQ SPSSKSNDTL 
       130        140        150        160        170        180 
SGISSIEPSK HSGSSHSLAS MVVVNSSSPT AACSGSWEAR GMEESVPTTD GSAESLYVQG 
       190        200        210        220        230        240 
MELFEEALQK WEQALSVGQR GDGGSTPTPG DSLQNPDTAS EALSEPESQR REFAEKLESL 
       250        260        270        280        290        300 
LHRAYHLQEE FGSTFPSDSM LLDLERTLML PLTEGSLRLR ADDEDSLTSE DSFFSATEIF 
       310        320        330        340        350        360 
ESLQIGEYPL PLSRPAAAYE EALQLVKEGR VPCRTLRTEL LGCYSDQDFL AKLHCVRQAF 
       370        380        390        400        410        420 
EGLLEERSNQ IFFGEVGRQM VTGLMTKAEK SPKGFLESYE EMLSYALRPE TWATTRLELE 
       430        440        450        460        470        480 
GRGVACMSFF DIVLDFILMD AFEDLENPPS SVLAVLRNRW LSDSFKETAL ATACWSVLKA 
       490        500        510        520        530        540 
KRRLLMVPDG FISHFYSVSE HVSPVLAFGF LGPKPQLSEV CAFFKHQIVQ YLRDMFDLDN 
       550        560        570        580        590    
VRYTSVPALA EDILQLSRRR SEILLGYLGA PVASSIGLNG PLPRENGPLE ELQ

Isoforms

- Isoform 2 of Protein FAM73B - Isoform 2 of Mitoguardin 2

Sequence View

        10         20         30         40         50         60 
MAFRRTEGMS MIQALAMTVA EIPVFLYTTF GQSAFSQLRL TPGLRKVLFA TALGTVALAL 
        70         80         90        100        110        120 
AAHQLKRRRR KKKQVGPEMG GEQLGTVPMP ILMARKVPSV KKGCSSRRVQ SPSSKSNDTL 
       130        140        150        160        170        180 
SGISSIEPSK HSGSSHSLAS MVVVNSSSPT AACSGSWEAR GMEESVPTTD GSAESLYVQG 
       190        200        210        220        230        240 
MELFEEALQK WEQALSVGQR GDGGSTPTPG DSLQNPDTAS EALSEPESQR REFAEKLESL 
       250        260        270        280        290        300 
LHRAYHLQEE FGSTFPSDSM LLDLERTLML PLTEGSLRLR ADDEDSLTSE DSFFSATEIF 
       310        320        330        340        350        360 
ESLQIGEYPL PLSRPAAAYE EALQLVKEGR VPCRTLRTEL LGCYSDQDFL AKLHCVRQAF 
       370        380        390        400        410        420 
EGLLEERSNQ IFFGEVGRQM VTGLMTKAEK SPKGFLESYE EMLSYALRPE TWATTRLELE 
       430        440        450        460        470        480 
GRGVACMSFF DIVLDFILMD AFEDLENPPS SVLAVLRNRW LSDSFKETAL ATACWSVLKA 
       490        500        510        520        530        540 
KRRLLMVPDG FISHFYSVSE HVSPVLAFGF LGPKPQLSEV CAFFKHQIVQ YLRDMFDLDN 
       550        560        570        580        590    
VRYTSVPALA EDILQLSRRR SEILLGYLGA PVASSIGLNG PLPRENGPLE ELQ         10         20         30         40         50         60 
MAFRRTEGMS MIQALAMTVA EIPVFLYTTF GQSAFSQLRL TPGLRKVLFA TALGTVALAL 
        70         80         90        100        110        120 
AAHQLKRRRR KKKQVGPEMG GEQLGTVPMP ILMARKVPSV KKGCSSRRVQ SPSSKSNDTL 
       130        140        150        160        170        180 
SGISSIEPSK HSGSSHSLAS MVVVNSSSPT AACSGSWEAR GMEESVPTTD GSAESLYVQG 
       190        200        210        220        230        240 
MELFEEALQK WEQALSVGQR GDGGSTPTPG DSLQNPDTAS EALSEPESQR REFAEKLESL 
       250        260        270        280        290        300 
LHRAYHLQEE FGSTFPSDSM LLDLERTLML PLTEGSLRLR ADDEDSLTSE DSFFSATEIF 
       310        320        330        340        350        360 
ESLQIGEYPL PLSRPAAAYE EALQLVKEGR VPCRTLRTEL LGCYSDQDFL AKLHCVRQAF 
       370        380        390        400        410        420 
EGLLEERSNQ IFFGEVGRQM VTGLMTKAEK SPKGFLESYE EMLSYALRPE TWATTRLELE 
       430        440        450        460        470        480 
GRGVACMSFF DIVLDFILMD AFEDLENPPS SVLAVLRNRW LSDSFKETAL ATACWSVLKA 
       490        500        510        520        530        540 
KRRLLMVPDG FISHFYSVSE HVSPVLAFGF LGPKPQLSEV CAFFKHQIVQ YLRDMFDLDN 
       550        560        570        580        590    
VRYTSVPALA EDILQLSRRR SEILLGYLGA PVASSIGLNG PLPRENGPLE ELQ



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8BK03-1-unknown MAFRRT... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8BK03-1-unknown MAFRRT... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt74674

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LEELQ 593 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)