TopFIND 4.0

Q8BN21: Serine/threonine-protein kinase VRK2

General Information

Protein names
- Serine/threonine-protein kinase VRK2
- 2.7.11.1
- Vaccinia-related kinase 2
Gene names Vrk2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8BN21

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAPRRKEKYK LPVPLPEGKI LDDMEGNRWA LGKMIGSGGF GLIYLAFPTN KPNKDARHVI 
        70         80         90        100        110        120 
KLEYQENGPL FSELKFYQRA AKRECIQKWI QQRKLDYLGI PVFYGFGLTD FKGRSYRFMV 
       130        140        150        160        170        180 
MERLGIDLQK LLDQNGGFKK LTVLQLGIRM LDVLEYIHEN EYVHGDIKAA NLLLDFTNPD 
       190        200        210        220        230        240 
RVYLADYGLS YRYCPNGNHK QYQEDPRKGH NGTIEFTSLD AHKGVAPSRR SDVEILGYCM 
       250        260        270        280        290        300 
LHWLFGKLPW EAKLDDPVAV QTAKTNLLDE LPESVLKWAP SGSSCSELVK YLMYVHNLAY 
       310        320        330        340        350        360 
DDKPDYQKLK KILNPDGVPL GPLEFSTKVQ SVHVRTPAQQ KVDSPKATRK PANEFPAKFP 
       370        380        390        400        410        420 
KKVHRETRAR QREEQEDSQP TMLQSRPAAP ENSRTRKIHE YSDIFSEMQS LQQTPSYMSF 
       430        440        450        460        470        480 
QGSYCKPYLD CTRRDPIRKP RSLPRYRHTP TGNLGVTDLE SSPRFWPAIF QLTLSEETKA 
       490        500    
DVYYYGITIF CLLIFVFLAL YFL

Isoforms

- Isoform 2 of Serine/threonine-protein kinase VRK2 - Isoform 3 of Serine/threonine-protein kinase VRK2

Sequence View

        10         20         30         40         50         60 
MAPRRKEKYK LPVPLPEGKI LDDMEGNRWA LGKMIGSGGF GLIYLAFPTN KPNKDARHVI 
        70         80         90        100        110        120 
KLEYQENGPL FSELKFYQRA AKRECIQKWI QQRKLDYLGI PVFYGFGLTD FKGRSYRFMV 
       130        140        150        160        170        180 
MERLGIDLQK LLDQNGGFKK LTVLQLGIRM LDVLEYIHEN EYVHGDIKAA NLLLDFTNPD 
       190        200        210        220        230        240 
RVYLADYGLS YRYCPNGNHK QYQEDPRKGH NGTIEFTSLD AHKGVAPSRR SDVEILGYCM 
       250        260        270        280        290        300 
LHWLFGKLPW EAKLDDPVAV QTAKTNLLDE LPESVLKWAP SGSSCSELVK YLMYVHNLAY 
       310        320        330        340        350        360 
DDKPDYQKLK KILNPDGVPL GPLEFSTKVQ SVHVRTPAQQ KVDSPKATRK PANEFPAKFP 
       370        380        390        400        410        420 
KKVHRETRAR QREEQEDSQP TMLQSRPAAP ENSRTRKIHE YSDIFSEMQS LQQTPSYMSF 
       430        440        450        460        470        480 
QGSYCKPYLD CTRRDPIRKP RSLPRYRHTP TGNLGVTDLE SSPRFWPAIF QLTLSEETKA 
       490        500    
DVYYYGITIF CLLIFVFLAL YFL         10         20         30         40         50         60 
MAPRRKEKYK LPVPLPEGKI LDDMEGNRWA LGKMIGSGGF GLIYLAFPTN KPNKDARHVI 
        70         80         90        100        110        120 
KLEYQENGPL FSELKFYQRA AKRECIQKWI QQRKLDYLGI PVFYGFGLTD FKGRSYRFMV 
       130        140        150        160        170        180 
MERLGIDLQK LLDQNGGFKK LTVLQLGIRM LDVLEYIHEN EYVHGDIKAA NLLLDFTNPD 
       190        200        210        220        230        240 
RVYLADYGLS YRYCPNGNHK QYQEDPRKGH NGTIEFTSLD AHKGVAPSRR SDVEILGYCM 
       250        260        270        280        290        300 
LHWLFGKLPW EAKLDDPVAV QTAKTNLLDE LPESVLKWAP SGSSCSELVK YLMYVHNLAY 
       310        320        330        340        350        360 
DDKPDYQKLK KILNPDGVPL GPLEFSTKVQ SVHVRTPAQQ KVDSPKATRK PANEFPAKFP 
       370        380        390        400        410        420 
KKVHRETRAR QREEQEDSQP TMLQSRPAAP ENSRTRKIHE YSDIFSEMQS LQQTPSYMSF 
       430        440        450        460        470        480 
QGSYCKPYLD CTRRDPIRKP RSLPRYRHTP TGNLGVTDLE SSPRFWPAIF QLTLSEETKA 
       490        500    
DVYYYGITIF CLLIFVFLAL YFL



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8BN21-1-unknown MAPRRK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8BN21-1-unknown MAPRRK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt94302
    Q8BN21-1-unknown MAPRRK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt94303

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ALYFL 503 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ALYFL 503 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt89920

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)