Q8BNE1: TRPM8 channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2}

General Information

Protein names	- TRPM8 channel-associated factor 1 {ECO:0000250\|UniProtKB:Q9Y4C2} - TRP channel-associated factor 1 {ECO:0000250\|UniProtKB:Q9Y4C2}
Gene names	Fam115a
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8BNE1

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MATPSAAFEA LMNGVTSWDI PEDSVPCELL LIGEASFPIM VNDVGQVLVA ASSYGRGRMV
        70         80         90        100        110        120
VASHEDFLLE SQLFVFLVNA VGWLRSSPNS AIGVHSSLAP LVKILESCGI ESKIEPEVND
       130        140        150        160        170        180
SLGVYCIDAY NETMTDKLVQ FVKRGGGLLI GGEAWDWDTQ GDDDRVLFAF PGNLVTSVAG
       190        200        210        220        230        240
VYFTDNKADT SFFKVSKKMP KIPILVRCDD DLSDDRDELL RGIIDLDITN SDCFPSQLLV
       250        260        270        280        290        300
HGSLAFPLGL DTYHGCVIAA ARYGRGRVVV TGHKVLFTVG KLGPFLLNAV RWLDGGRKGK
       310        320        330        340        350        360
IVVQTELRTL SGLLAVGGID TSIEPHLTSD ASVYCFEPTS DVGVKELQEF VAEGGGLFVG
       370        380        390        400        410        420
TQAWWWAFKN PGVSPLARFP GNLLLNAFGI SITSQSLNPG PFRTPKIGTR TYHFRSTLAE
       430        440        450        460        470        480
FQVIMGRKRG NVEKGWLAKL GPDGATFLQI PAEEIPAYMS VHRLLRKLLS RYRLPVATRE
       490        500        510        520        530        540
NPVINDCCRG AMLSLATGLA HSGSDLSLLI PEIEDVYSSR YLRPSASPIT VNVNCTNPGT
       550        560        570        580        590        600
RYCWMSTGLY IPGRQVIDVS VPESAASADL KIQIGCHTDD LTRASKLFRG PLVINRCCLD
       610        620        630        640        650        660
KPTKSITCLW GGLLYIIVPQ NSKLGSVPLT VKGAVRAPFY KLGETSKEEW KRRLLEYPGP
       670        680        690        700        710        720
WGELATDNII LTVPTANLRT LENPEPLLRL WDEMMQAVAK LGGETFPLRL PQRIVADVQI
       730        740        750        760        770        780
SVGWMHAGYP IMCHLESVQE LINEKLIRTK GLWGPVHELG RNQQRQEWEF PPHTTEATCN
       790        800        810        820        830        840
LWCVYVHETV LGIPRSRANI ALWPPVREKR VRIYLSKGPS VKHWNAWTAL ETYLQLQEAF
       850        860        870        880        890        900
GWEPFIRLFT EYRNQTTSSS PPSDNVDKMN LWVKMFSQQV QRNLAPFFEA WGWPIQKEVA
       910        920
TSLAYLPEWK ENIMKLYLLT QMPH

Isoforms

- Isoform 2 of Protein FAM115A - Isoform 3 of Protein FAM115A - Isoform 4 of Protein FAM115A - Isoform 2 of TRPM8 channel-associated factor 1 - Isoform 3 of TRPM8 channel-associated factor 1 - Isoform 4 of TRPM8 channel-associated factor 1

Sequence View

        10         20         30         40         50         60
MATPSAAFEA LMNGVTSWDI PEDSVPCELL LIGEASFPIM VNDVGQVLVA ASSYGRGRMV
        70         80         90        100        110        120
VASHEDFLLE SQLFVFLVNA VGWLRSSPNS AIGVHSSLAP LVKILESCGI ESKIEPEVND
       130        140        150        160        170        180
SLGVYCIDAY NETMTDKLVQ FVKRGGGLLI GGEAWDWDTQ GDDDRVLFAF PGNLVTSVAG
       190        200        210        220        230        240
VYFTDNKADT SFFKVSKKMP KIPILVRCDD DLSDDRDELL RGIIDLDITN SDCFPSQLLV
       250        260        270        280        290        300
HGSLAFPLGL DTYHGCVIAA ARYGRGRVVV TGHKVLFTVG KLGPFLLNAV RWLDGGRKGK
       310        320        330        340        350        360
IVVQTELRTL SGLLAVGGID TSIEPHLTSD ASVYCFEPTS DVGVKELQEF VAEGGGLFVG
       370        380        390        400        410        420
TQAWWWAFKN PGVSPLARFP GNLLLNAFGI SITSQSLNPG PFRTPKIGTR TYHFRSTLAE
       430        440        450        460        470        480
FQVIMGRKRG NVEKGWLAKL GPDGATFLQI PAEEIPAYMS VHRLLRKLLS RYRLPVATRE
       490        500        510        520        530        540
NPVINDCCRG AMLSLATGLA HSGSDLSLLI PEIEDVYSSR YLRPSASPIT VNVNCTNPGT
       550        560        570        580        590        600
RYCWMSTGLY IPGRQVIDVS VPESAASADL KIQIGCHTDD LTRASKLFRG PLVINRCCLD
       610        620        630        640        650        660
KPTKSITCLW GGLLYIIVPQ NSKLGSVPLT VKGAVRAPFY KLGETSKEEW KRRLLEYPGP
       670        680        690        700        710        720
WGELATDNII LTVPTANLRT LENPEPLLRL WDEMMQAVAK LGGETFPLRL PQRIVADVQI
       730        740        750        760        770        780
SVGWMHAGYP IMCHLESVQE LINEKLIRTK GLWGPVHELG RNQQRQEWEF PPHTTEATCN
       790        800        810        820        830        840
LWCVYVHETV LGIPRSRANI ALWPPVREKR VRIYLSKGPS VKHWNAWTAL ETYLQLQEAF
       850        860        870        880        890        900
GWEPFIRLFT EYRNQTTSSS PPSDNVDKMN LWVKMFSQQV QRNLAPFFEA WGWPIQKEVA
       910        920
TSLAYLPEWK ENIMKLYLLT QMPH         10         20         30         40         50         60
MATPSAAFEA LMNGVTSWDI PEDSVPCELL LIGEASFPIM VNDVGQVLVA ASSYGRGRMV
        70         80         90        100        110        120
VASHEDFLLE SQLFVFLVNA VGWLRSSPNS AIGVHSSLAP LVKILESCGI ESKIEPEVND
       130        140        150        160        170        180
SLGVYCIDAY NETMTDKLVQ FVKRGGGLLI GGEAWDWDTQ GDDDRVLFAF PGNLVTSVAG
       190        200        210        220        230        240
VYFTDNKADT SFFKVSKKMP KIPILVRCDD DLSDDRDELL RGIIDLDITN SDCFPSQLLV
       250        260        270        280        290        300
HGSLAFPLGL DTYHGCVIAA ARYGRGRVVV TGHKVLFTVG KLGPFLLNAV RWLDGGRKGK
       310        320        330        340        350        360
IVVQTELRTL SGLLAVGGID TSIEPHLTSD ASVYCFEPTS DVGVKELQEF VAEGGGLFVG
       370        380        390        400        410        420
TQAWWWAFKN PGVSPLARFP GNLLLNAFGI SITSQSLNPG PFRTPKIGTR TYHFRSTLAE
       430        440        450        460        470        480
FQVIMGRKRG NVEKGWLAKL GPDGATFLQI PAEEIPAYMS VHRLLRKLLS RYRLPVATRE
       490        500        510        520        530        540
NPVINDCCRG AMLSLATGLA HSGSDLSLLI PEIEDVYSSR YLRPSASPIT VNVNCTNPGT
       550        560        570        580        590        600
RYCWMSTGLY IPGRQVIDVS VPESAASADL KIQIGCHTDD LTRASKLFRG PLVINRCCLD
       610        620        630        640        650        660
KPTKSITCLW GGLLYIIVPQ NSKLGSVPLT VKGAVRAPFY KLGETSKEEW KRRLLEYPGP
       670        680        690        700        710        720
WGELATDNII LTVPTANLRT LENPEPLLRL WDEMMQAVAK LGGETFPLRL PQRIVADVQI
       730        740        750        760        770        780
SVGWMHAGYP IMCHLESVQE LINEKLIRTK GLWGPVHELG RNQQRQEWEF PPHTTEATCN
       790        800        810        820        830        840
LWCVYVHETV LGIPRSRANI ALWPPVREKR VRIYLSKGPS VKHWNAWTAL ETYLQLQEAF
       850        860        870        880        890        900
GWEPFIRLFT EYRNQTTSSS PPSDNVDKMN LWVKMFSQQV QRNLAPFFEA WGWPIQKEVA
       910        920
TSLAYLPEWK ENIMKLYLLT QMPH         10         20         30         40         50         60
MATPSAAFEA LMNGVTSWDI PEDSVPCELL LIGEASFPIM VNDVGQVLVA ASSYGRGRMV
        70         80         90        100        110        120
VASHEDFLLE SQLFVFLVNA VGWLRSSPNS AIGVHSSLAP LVKILESCGI ESKIEPEVND
       130        140        150        160        170        180
SLGVYCIDAY NETMTDKLVQ FVKRGGGLLI GGEAWDWDTQ GDDDRVLFAF PGNLVTSVAG
       190        200        210        220        230        240
VYFTDNKADT SFFKVSKKMP KIPILVRCDD DLSDDRDELL RGIIDLDITN SDCFPSQLLV
       250        260        270        280        290        300
HGSLAFPLGL DTYHGCVIAA ARYGRGRVVV TGHKVLFTVG KLGPFLLNAV RWLDGGRKGK
       310        320        330        340        350        360
IVVQTELRTL SGLLAVGGID TSIEPHLTSD ASVYCFEPTS DVGVKELQEF VAEGGGLFVG
       370        380        390        400        410        420
TQAWWWAFKN PGVSPLARFP GNLLLNAFGI SITSQSLNPG PFRTPKIGTR TYHFRSTLAE
       430        440        450        460        470        480
FQVIMGRKRG NVEKGWLAKL GPDGATFLQI PAEEIPAYMS VHRLLRKLLS RYRLPVATRE
       490        500        510        520        530        540
NPVINDCCRG AMLSLATGLA HSGSDLSLLI PEIEDVYSSR YLRPSASPIT VNVNCTNPGT
       550        560        570        580        590        600
RYCWMSTGLY IPGRQVIDVS VPESAASADL KIQIGCHTDD LTRASKLFRG PLVINRCCLD
       610        620        630        640        650        660
KPTKSITCLW GGLLYIIVPQ NSKLGSVPLT VKGAVRAPFY KLGETSKEEW KRRLLEYPGP
       670        680        690        700        710        720
WGELATDNII LTVPTANLRT LENPEPLLRL WDEMMQAVAK LGGETFPLRL PQRIVADVQI
       730        740        750        760        770        780
SVGWMHAGYP IMCHLESVQE LINEKLIRTK GLWGPVHELG RNQQRQEWEF PPHTTEATCN
       790        800        810        820        830        840
LWCVYVHETV LGIPRSRANI ALWPPVREKR VRIYLSKGPS VKHWNAWTAL ETYLQLQEAF
       850        860        870        880        890        900
GWEPFIRLFT EYRNQTTSSS PPSDNVDKMN LWVKMFSQQV QRNLAPFFEA WGWPIQKEVA
       910        920
TSLAYLPEWK ENIMKLYLLT QMPH         10         20         30         40         50         60
MATPSAAFEA LMNGVTSWDI PEDSVPCELL LIGEASFPIM VNDVGQVLVA ASSYGRGRMV
        70         80         90        100        110        120
VASHEDFLLE SQLFVFLVNA VGWLRSSPNS AIGVHSSLAP LVKILESCGI ESKIEPEVND
       130        140        150        160        170        180
SLGVYCIDAY NETMTDKLVQ FVKRGGGLLI GGEAWDWDTQ GDDDRVLFAF PGNLVTSVAG
       190        200        210        220        230        240
VYFTDNKADT SFFKVSKKMP KIPILVRCDD DLSDDRDELL RGIIDLDITN SDCFPSQLLV
       250        260        270        280        290        300
HGSLAFPLGL DTYHGCVIAA ARYGRGRVVV TGHKVLFTVG KLGPFLLNAV RWLDGGRKGK
       310        320        330        340        350        360
IVVQTELRTL SGLLAVGGID TSIEPHLTSD ASVYCFEPTS DVGVKELQEF VAEGGGLFVG
       370        380        390        400        410        420
TQAWWWAFKN PGVSPLARFP GNLLLNAFGI SITSQSLNPG PFRTPKIGTR TYHFRSTLAE
       430        440        450        460        470        480
FQVIMGRKRG NVEKGWLAKL GPDGATFLQI PAEEIPAYMS VHRLLRKLLS RYRLPVATRE
       490        500        510        520        530        540
NPVINDCCRG AMLSLATGLA HSGSDLSLLI PEIEDVYSSR YLRPSASPIT VNVNCTNPGT
       550        560        570        580        590        600
RYCWMSTGLY IPGRQVIDVS VPESAASADL KIQIGCHTDD LTRASKLFRG PLVINRCCLD
       610        620        630        640        650        660
KPTKSITCLW GGLLYIIVPQ NSKLGSVPLT VKGAVRAPFY KLGETSKEEW KRRLLEYPGP
       670        680        690        700        710        720
WGELATDNII LTVPTANLRT LENPEPLLRL WDEMMQAVAK LGGETFPLRL PQRIVADVQI
       730        740        750        760        770        780
SVGWMHAGYP IMCHLESVQE LINEKLIRTK GLWGPVHELG RNQQRQEWEF PPHTTEATCN
       790        800        810        820        830        840
LWCVYVHETV LGIPRSRANI ALWPPVREKR VRIYLSKGPS VKHWNAWTAL ETYLQLQEAF
       850        860        870        880        890        900
GWEPFIRLFT EYRNQTTSSS PPSDNVDKMN LWVKMFSQQV QRNLAPFFEA WGWPIQKEVA
       910        920
TSLAYLPEWK ENIMKLYLLT QMPH         10         20         30         40         50         60
MATPSAAFEA LMNGVTSWDI PEDSVPCELL LIGEASFPIM VNDVGQVLVA ASSYGRGRMV
        70         80         90        100        110        120
VASHEDFLLE SQLFVFLVNA VGWLRSSPNS AIGVHSSLAP LVKILESCGI ESKIEPEVND
       130        140        150        160        170        180
SLGVYCIDAY NETMTDKLVQ FVKRGGGLLI GGEAWDWDTQ GDDDRVLFAF PGNLVTSVAG
       190        200        210        220        230        240
VYFTDNKADT SFFKVSKKMP KIPILVRCDD DLSDDRDELL RGIIDLDITN SDCFPSQLLV
       250        260        270        280        290        300
HGSLAFPLGL DTYHGCVIAA ARYGRGRVVV TGHKVLFTVG KLGPFLLNAV RWLDGGRKGK
       310        320        330        340        350        360
IVVQTELRTL SGLLAVGGID TSIEPHLTSD ASVYCFEPTS DVGVKELQEF VAEGGGLFVG
       370        380        390        400        410        420
TQAWWWAFKN PGVSPLARFP GNLLLNAFGI SITSQSLNPG PFRTPKIGTR TYHFRSTLAE
       430        440        450        460        470        480
FQVIMGRKRG NVEKGWLAKL GPDGATFLQI PAEEIPAYMS VHRLLRKLLS RYRLPVATRE
       490        500        510        520        530        540
NPVINDCCRG AMLSLATGLA HSGSDLSLLI PEIEDVYSSR YLRPSASPIT VNVNCTNPGT
       550        560        570        580        590        600
RYCWMSTGLY IPGRQVIDVS VPESAASADL KIQIGCHTDD LTRASKLFRG PLVINRCCLD
       610        620        630        640        650        660
KPTKSITCLW GGLLYIIVPQ NSKLGSVPLT VKGAVRAPFY KLGETSKEEW KRRLLEYPGP
       670        680        690        700        710        720
WGELATDNII LTVPTANLRT LENPEPLLRL WDEMMQAVAK LGGETFPLRL PQRIVADVQI
       730        740        750        760        770        780
SVGWMHAGYP IMCHLESVQE LINEKLIRTK GLWGPVHELG RNQQRQEWEF PPHTTEATCN
       790        800        810        820        830        840
LWCVYVHETV LGIPRSRANI ALWPPVREKR VRIYLSKGPS VKHWNAWTAL ETYLQLQEAF
       850        860        870        880        890        900
GWEPFIRLFT EYRNQTTSSS PPSDNVDKMN LWVKMFSQQV QRNLAPFFEA WGWPIQKEVA
       910        920
TSLAYLPEWK ENIMKLYLLT QMPH         10         20         30         40         50         60
MATPSAAFEA LMNGVTSWDI PEDSVPCELL LIGEASFPIM VNDVGQVLVA ASSYGRGRMV
        70         80         90        100        110        120
VASHEDFLLE SQLFVFLVNA VGWLRSSPNS AIGVHSSLAP LVKILESCGI ESKIEPEVND
       130        140        150        160        170        180
SLGVYCIDAY NETMTDKLVQ FVKRGGGLLI GGEAWDWDTQ GDDDRVLFAF PGNLVTSVAG
       190        200        210        220        230        240
VYFTDNKADT SFFKVSKKMP KIPILVRCDD DLSDDRDELL RGIIDLDITN SDCFPSQLLV
       250        260        270        280        290        300
HGSLAFPLGL DTYHGCVIAA ARYGRGRVVV TGHKVLFTVG KLGPFLLNAV RWLDGGRKGK
       310        320        330        340        350        360
IVVQTELRTL SGLLAVGGID TSIEPHLTSD ASVYCFEPTS DVGVKELQEF VAEGGGLFVG
       370        380        390        400        410        420
TQAWWWAFKN PGVSPLARFP GNLLLNAFGI SITSQSLNPG PFRTPKIGTR TYHFRSTLAE
       430        440        450        460        470        480
FQVIMGRKRG NVEKGWLAKL GPDGATFLQI PAEEIPAYMS VHRLLRKLLS RYRLPVATRE
       490        500        510        520        530        540
NPVINDCCRG AMLSLATGLA HSGSDLSLLI PEIEDVYSSR YLRPSASPIT VNVNCTNPGT
       550        560        570        580        590        600
RYCWMSTGLY IPGRQVIDVS VPESAASADL KIQIGCHTDD LTRASKLFRG PLVINRCCLD
       610        620        630        640        650        660
KPTKSITCLW GGLLYIIVPQ NSKLGSVPLT VKGAVRAPFY KLGETSKEEW KRRLLEYPGP
       670        680        690        700        710        720
WGELATDNII LTVPTANLRT LENPEPLLRL WDEMMQAVAK LGGETFPLRL PQRIVADVQI
       730        740        750        760        770        780
SVGWMHAGYP IMCHLESVQE LINEKLIRTK GLWGPVHELG RNQQRQEWEF PPHTTEATCN
       790        800        810        820        830        840
LWCVYVHETV LGIPRSRANI ALWPPVREKR VRIYLSKGPS VKHWNAWTAL ETYLQLQEAF
       850        860        870        880        890        900
GWEPFIRLFT EYRNQTTSSS PPSDNVDKMN LWVKMFSQQV QRNLAPFFEA WGWPIQKEVA
       910        920
TSLAYLPEWK ENIMKLYLLT QMPH

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8BNE1-1-unknown	MATPSA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8BNE1-1-unknown	MATPSA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74387
Q8BNE1-1-unknown	MATPSA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74389
Q8BNE1-425-unknown	MGRKRG...	425	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74388
Q8BNE1-425-unknown	MGRKRG...	425	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt104225

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PILVRC	207	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70007
...PILVRC	207	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91949
...LLTQMP	922	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70006
...LLTQMP	922	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70005
...TQMPH	924	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

TopFIND

Q8BNE1: TRPM8 channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2}

General Information

2

N-termini

3

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates