Q8BQ48: Centrosomal protein of 295 kDa {ECO:0000305}
| Protein names | - Centrosomal protein of 295 kDa {ECO:0000305} |
|---|---|
| Gene names | Kiaa1731 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q8BQ48 |
1
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MKRKGMNTKL RLSPSEEAFI LKEDYERRRK LRLLQVREQE RGIAFQIREG IKQRRSQQVS
70 80 90 100 110 120
HLAEELRAKW EEAQSQKIQN LEKLYLASLR HMGDGHRQAK ENEPDLDALS RRAAERKRKA
130 140 150 160 170 180
EVRHKEALKV QKNQKEMLMK QKTRHIKARK EAVLVEKQRS AKMARLPPPV PSPFENIDVN
190 200 210 220 230 240
RIPSLKTNSS TYHHISTFVS RQMGTKQPDA HLAAEEEARR VERLRKQAAQ ERVKQFERAH
250 260 270 280 290 300
VRGSQAMKKI HLAQNQERLM EELKQLQKED LARRRQTVAQ MPPQMLELPY RRSEMKEDRQ
310 320 330 340 350 360
RELEFAFEDM YNADRKVKGN LILHLKPEPL PTISDQLQDE ELDLSMEQEN QVPLAAKIQQ
370 380 390 400 410 420
IPSRILFKRL LNKIRSQKSL WTIKSVSEDE GEVTSSIIEI ESKVPSVDSG AIITEERTAA
430 440 450 460 470 480
SFEQEQVTDS DRLTIESGPL SSEDKPLYYK AGTGREQAMA VSPPATAVAQ SSVLLHPQEE
490 500 510 520 530 540
AVRIRMSLRR KQIMEIEEQK QKQLELLEQI EQQKLRLETD CFRAQLEEQR KQADQPEVCC
550 560 570 580 590 600
APMSHAMISD EDSHRQMIRN YQHQLLQQNR LHKETVETAR KRLLEYQTVL KERSPSLSAS
610 620 630 640 650 660
ALVPDSVVSG PPQQSYKPAA ASDSWDPSQR LKLSPSKYQP VQPSQIPALE QSHIQVPRHG
670 680 690 700 710 720
HITQRQGKMA VSEMLGKQPV ESQERQWQFS QVETHQGDYE FVLKDSHSLS RTLSYVRPQT
730 740 750 760 770 780
LQDAREVSKP PRVIICQSLD SQQISSEDSE NISSKPSEPS PFLPLVPERP FTSLPVKFHS
790 800 810 820 830 840
GTIHKPFTTI NQSVISQMHD QPLSSSETIT AQQGDLRFLQ EQLELQKKVL QARQEAREKL
850 860 870 880 890 900
LLCTQKELGQ QTGLPVFLPS PAGNIFSSLP SASAESGNFQ TSSTKSDATV SSDNMDRLWD
910 920 930 940 950 960
SSQPISSQQT HLEFLQEQSS VETDNLQARR EAQEVLFAHT QNTLEKIVRS EQAGSSLPHQ
970 980 990 1000 1010 1020
VAQQSFSSLT LADTQSKKIQ KQPLPANKKG LLPSQSEVSK AQDGSSGFLQ QTLPLQNTLK
1030 1040 1050 1060 1070 1080
LLQEQLTRQR SMIPPRRDGQ ETLLLYKESC SEDSEAGPVE SLSSVVVQHA DASRAVSEVP
1090 1100 1110 1120 1130 1140
KRLQDVYSSE EENRVLSSHL ITHGFPQHSL QRQEHFTPLQ EETHIQRLIL GARKNNEEFA
1150 1160 1170 1180 1190 1200
PKQNELEKGL CSQQTDALSS PSQVTDWGTS RGSVSVRSDR TDPLRHFKIP AFRERLVRVS
1210 1220 1230 1240 1250 1260
QHTFPLQDNL QEHQEWVDTE KESFQSSPLT PENPSSQQTG FSSFKASLRL PSCVSLPSAD
1270 1280 1290 1300 1310 1320
SGITQHPLST ESDSKVKSSH LQIPELQHRL SKISQLIPPQ QDSLKALQEQ LATQREAIIH
1330 1340 1350 1360 1370 1380
SRQEAHEETL REWKEKIFPE QVGPFSPLIP QHSLASFPVS DTERAQELCS TNSDTISSGY
1390 1400 1410 1420 1430 1440
PEMLELPDRT LGLSHTALPQ QNNLTAHPEH LHAQTNFFHS TEKAQEGLVF PRPCQFEEMS
1450 1460 1470 1480 1490 1500
AEHFIQPQHD DLKALQQQLD MQREAIRSGQ EMQEKMLLQR LNKLEQRISS KQISSSLFSS
1510 1520 1530 1540 1550 1560
QVALPIANSD GTLQSFPTKS NETELLGSQD EYLSFSQPRL PLQNNMTEQL DLEKVFHKEL
1570 1580 1590 1600 1610 1620
LLHKQKSQNK SESSEHSLPP LFLSKEIEHP FISLPFAESK SKSICELYLS DKKHAAPNDA
1630 1640 1650 1660 1670 1680
VIPRLQDRLL SCSQPVLTQQ DNMSLQKQLN LQRETLHSRQ KAQEELLVQR QTSLQQQIQR
1690 1700 1710 1720 1730 1740
HRETLKNFFN VSQARNPTDE NDLEMQKREQ LGGWFPHTQG LTWGDAGQGS ANGEQPRADV
1750 1760 1770 1780 1790 1800
HAEHNGESLA KELSGRASKP PVSKVKCVLD LNQHELSTIQ EVESPASGRI SMPGKAEFYQ
1810 1820 1830 1840 1850 1860
DRDPLRVSVS REQSFLESPL AHDPFGCHQP PAQENSKSHD DNAEAVKVKK SDVEDHAVLS
1870 1880 1890 1900 1910 1920
HAVSKEEACT NLGPLGKPDD EAETQEISQE PLSSVTVSTG SFLSYEITDL SLTDPESFSE
1930 1940 1950 1960 1970 1980
QTEHLEQEST NKQEETDPLS IAVPSVIYQQ QHSLGAHNSL LPMEEESTSD HTHVQQIMDN
1990 2000 2010 2020 2030 2040
DVNEANLIPD KRDFQVPAVD LDFRELEHIF PHLHRQLFKP LEPHLDFDLS SPGTSQEDSD
2050 2060 2070 2080 2090 2100
FYQSSESSSE KHVKALSTGT ICFPALTAKS HSPNPRLNQL DINLAHATTE GSEQSFQQLR
2110 2120 2130 2140 2150 2160
PEFSSQESQH ADLPSIYSIE ARGPSQRMEN QNYSEMLQNK KKSLSLQPST EDLTPACSSS
2170 2180 2190 2200 2210 2220
DTALFDQLHL QHSTPCASVS SECSVKLLES REEVLGFEEL SRRAVTMSQR LTEDENVVLP
2230 2240 2250 2260 2270 2280
INPHVGRVEK EASVQGSNPL SIQNEKPIQN FIETDTTEAV GNVCQLAQAE HILKSCPFRS
2290 2300 2310 2320 2330 2340
PIPIWETDTG YGIMEEPDLT LVSNSDISIT ETDLANLTLE DREDNEAQFF QAGVVLPTSS
2350 2360 2370 2380 2390 2400
METSVCGAVS EPYVDQPTVA PSATSGSLQE AFMTRQTLTE RSYQRQREIW NKTRLPQTKV
2410
SKEKLPTGCT GS
Isoforms
- Isoform 2 of Centrosomal protein KIAA1731 homolog - Isoform 3 of Centrosomal protein KIAA1731 homolog - Isoform 4 of Centrosomal protein KIAA1731 homolog - Isoform 5 of Centrosomal protein KIAA1731 homolog - Isoform 6 of Centrosomal protein KIAA1731 homolog - Isoform 2 of Centrosomal protein of 295 kDa - Isoform 3 of Centrosomal protein of 295 kDa - Isoform 4 of Centrosomal protein of 295 kDa - Isoform 5 of Centrosomal protein of 295 kDa - Isoform 6 of Centrosomal protein of 295 kDaSequence View
10 20 30 40 50 60
MKRKGMNTKL RLSPSEEAFI LKEDYERRRK LRLLQVREQE RGIAFQIREG IKQRRSQQVS
70 80 90 100 110 120
HLAEELRAKW EEAQSQKIQN LEKLYLASLR HMGDGHRQAK ENEPDLDALS RRAAERKRKA
130 140 150 160 170 180
EVRHKEALKV QKNQKEMLMK QKTRHIKARK EAVLVEKQRS AKMARLPPPV PSPFENIDVN
190 200 210 220 230 240
RIPSLKTNSS TYHHISTFVS RQMGTKQPDA HLAAEEEARR VERLRKQAAQ ERVKQFERAH
250 260 270 280 290 300
VRGSQAMKKI HLAQNQERLM EELKQLQKED LARRRQTVAQ MPPQMLELPY RRSEMKEDRQ
310 320 330 340 350 360
RELEFAFEDM YNADRKVKGN LILHLKPEPL PTISDQLQDE ELDLSMEQEN QVPLAAKIQQ
370 380 390 400 410 420
IPSRILFKRL LNKIRSQKSL WTIKSVSEDE GEVTSSIIEI ESKVPSVDSG AIITEERTAA
430 440 450 460 470 480
SFEQEQVTDS DRLTIESGPL SSEDKPLYYK AGTGREQAMA VSPPATAVAQ SSVLLHPQEE
490 500 510 520 530 540
AVRIRMSLRR KQIMEIEEQK QKQLELLEQI EQQKLRLETD CFRAQLEEQR KQADQPEVCC
550 560 570 580 590 600
APMSHAMISD EDSHRQMIRN YQHQLLQQNR LHKETVETAR KRLLEYQTVL KERSPSLSAS
610 620 630 640 650 660
ALVPDSVVSG PPQQSYKPAA ASDSWDPSQR LKLSPSKYQP VQPSQIPALE QSHIQVPRHG
670 680 690 700 710 720
HITQRQGKMA VSEMLGKQPV ESQERQWQFS QVETHQGDYE FVLKDSHSLS RTLSYVRPQT
730 740 750 760 770 780
LQDAREVSKP PRVIICQSLD SQQISSEDSE NISSKPSEPS PFLPLVPERP FTSLPVKFHS
790 800 810 820 830 840
GTIHKPFTTI NQSVISQMHD QPLSSSETIT AQQGDLRFLQ EQLELQKKVL QARQEAREKL
850 860 870 880 890 900
LLCTQKELGQ QTGLPVFLPS PAGNIFSSLP SASAESGNFQ TSSTKSDATV SSDNMDRLWD
910 920 930 940 950 960
SSQPISSQQT HLEFLQEQSS VETDNLQARR EAQEVLFAHT QNTLEKIVRS EQAGSSLPHQ
970 980 990 1000 1010 1020
VAQQSFSSLT LADTQSKKIQ KQPLPANKKG LLPSQSEVSK AQDGSSGFLQ QTLPLQNTLK
1030 1040 1050 1060 1070 1080
LLQEQLTRQR SMIPPRRDGQ ETLLLYKESC SEDSEAGPVE SLSSVVVQHA DASRAVSEVP
1090 1100 1110 1120 1130 1140
KRLQDVYSSE EENRVLSSHL ITHGFPQHSL QRQEHFTPLQ EETHIQRLIL GARKNNEEFA
1150 1160 1170 1180 1190 1200
PKQNELEKGL CSQQTDALSS PSQVTDWGTS RGSVSVRSDR TDPLRHFKIP AFRERLVRVS
1210 1220 1230 1240 1250 1260
QHTFPLQDNL QEHQEWVDTE KESFQSSPLT PENPSSQQTG FSSFKASLRL PSCVSLPSAD
1270 1280 1290 1300 1310 1320
SGITQHPLST ESDSKVKSSH LQIPELQHRL SKISQLIPPQ QDSLKALQEQ LATQREAIIH
1330 1340 1350 1360 1370 1380
SRQEAHEETL REWKEKIFPE QVGPFSPLIP QHSLASFPVS DTERAQELCS TNSDTISSGY
1390 1400 1410 1420 1430 1440
PEMLELPDRT LGLSHTALPQ QNNLTAHPEH LHAQTNFFHS TEKAQEGLVF PRPCQFEEMS
1450 1460 1470 1480 1490 1500
AEHFIQPQHD DLKALQQQLD MQREAIRSGQ EMQEKMLLQR LNKLEQRISS KQISSSLFSS
1510 1520 1530 1540 1550 1560
QVALPIANSD GTLQSFPTKS NETELLGSQD EYLSFSQPRL PLQNNMTEQL DLEKVFHKEL
1570 1580 1590 1600 1610 1620
LLHKQKSQNK SESSEHSLPP LFLSKEIEHP FISLPFAESK SKSICELYLS DKKHAAPNDA
1630 1640 1650 1660 1670 1680
VIPRLQDRLL SCSQPVLTQQ DNMSLQKQLN LQRETLHSRQ KAQEELLVQR QTSLQQQIQR
1690 1700 1710 1720 1730 1740
HRETLKNFFN VSQARNPTDE NDLEMQKREQ LGGWFPHTQG LTWGDAGQGS ANGEQPRADV
1750 1760 1770 1780 1790 1800
HAEHNGESLA KELSGRASKP PVSKVKCVLD LNQHELSTIQ EVESPASGRI SMPGKAEFYQ
1810 1820 1830 1840 1850 1860
DRDPLRVSVS REQSFLESPL AHDPFGCHQP PAQENSKSHD DNAEAVKVKK SDVEDHAVLS
1870 1880 1890 1900 1910 1920
HAVSKEEACT NLGPLGKPDD EAETQEISQE PLSSVTVSTG SFLSYEITDL SLTDPESFSE
1930 1940 1950 1960 1970 1980
QTEHLEQEST NKQEETDPLS IAVPSVIYQQ QHSLGAHNSL LPMEEESTSD HTHVQQIMDN
1990 2000 2010 2020 2030 2040
DVNEANLIPD KRDFQVPAVD LDFRELEHIF PHLHRQLFKP LEPHLDFDLS SPGTSQEDSD
2050 2060 2070 2080 2090 2100
FYQSSESSSE KHVKALSTGT ICFPALTAKS HSPNPRLNQL DINLAHATTE GSEQSFQQLR
2110 2120 2130 2140 2150 2160
PEFSSQESQH ADLPSIYSIE ARGPSQRMEN QNYSEMLQNK KKSLSLQPST EDLTPACSSS
2170 2180 2190 2200 2210 2220
DTALFDQLHL QHSTPCASVS SECSVKLLES REEVLGFEEL SRRAVTMSQR LTEDENVVLP
2230 2240 2250 2260 2270 2280
INPHVGRVEK EASVQGSNPL SIQNEKPIQN FIETDTTEAV GNVCQLAQAE HILKSCPFRS
2290 2300 2310 2320 2330 2340
PIPIWETDTG YGIMEEPDLT LVSNSDISIT ETDLANLTLE DREDNEAQFF QAGVVLPTSS
2350 2360 2370 2380 2390 2400
METSVCGAVS EPYVDQPTVA PSATSGSLQE AFMTRQTLTE RSYQRQREIW NKTRLPQTKV
2410
SKEKLPTGCT GS
10 20 30 40 50 60
MKRKGMNTKL RLSPSEEAFI LKEDYERRRK LRLLQVREQE RGIAFQIREG IKQRRSQQVS
70 80 90 100 110 120
HLAEELRAKW EEAQSQKIQN LEKLYLASLR HMGDGHRQAK ENEPDLDALS RRAAERKRKA
130 140 150 160 170 180
EVRHKEALKV QKNQKEMLMK QKTRHIKARK EAVLVEKQRS AKMARLPPPV PSPFENIDVN
190 200 210 220 230 240
RIPSLKTNSS TYHHISTFVS RQMGTKQPDA HLAAEEEARR VERLRKQAAQ ERVKQFERAH
250 260 270 280 290 300
VRGSQAMKKI HLAQNQERLM EELKQLQKED LARRRQTVAQ MPPQMLELPY RRSEMKEDRQ
310 320 330 340 350 360
RELEFAFEDM YNADRKVKGN LILHLKPEPL PTISDQLQDE ELDLSMEQEN QVPLAAKIQQ
370 380 390 400 410 420
IPSRILFKRL LNKIRSQKSL WTIKSVSEDE GEVTSSIIEI ESKVPSVDSG AIITEERTAA
430 440 450 460 470 480
SFEQEQVTDS DRLTIESGPL SSEDKPLYYK AGTGREQAMA VSPPATAVAQ SSVLLHPQEE
490 500 510 520 530 540
AVRIRMSLRR KQIMEIEEQK QKQLELLEQI EQQKLRLETD CFRAQLEEQR KQADQPEVCC
550 560 570 580 590 600
APMSHAMISD EDSHRQMIRN YQHQLLQQNR LHKETVETAR KRLLEYQTVL KERSPSLSAS
610 620 630 640 650 660
ALVPDSVVSG PPQQSYKPAA ASDSWDPSQR LKLSPSKYQP VQPSQIPALE QSHIQVPRHG
670 680 690 700 710 720
HITQRQGKMA VSEMLGKQPV ESQERQWQFS QVETHQGDYE FVLKDSHSLS RTLSYVRPQT
730 740 750 760 770 780
LQDAREVSKP PRVIICQSLD SQQISSEDSE NISSKPSEPS PFLPLVPERP FTSLPVKFHS
790 800 810 820 830 840
GTIHKPFTTI NQSVISQMHD QPLSSSETIT AQQGDLRFLQ EQLELQKKVL QARQEAREKL
850 860 870 880 890 900
LLCTQKELGQ QTGLPVFLPS PAGNIFSSLP SASAESGNFQ TSSTKSDATV SSDNMDRLWD
910 920 930 940 950 960
SSQPISSQQT HLEFLQEQSS VETDNLQARR EAQEVLFAHT QNTLEKIVRS EQAGSSLPHQ
970 980 990 1000 1010 1020
VAQQSFSSLT LADTQSKKIQ KQPLPANKKG LLPSQSEVSK AQDGSSGFLQ QTLPLQNTLK
1030 1040 1050 1060 1070 1080
LLQEQLTRQR SMIPPRRDGQ ETLLLYKESC SEDSEAGPVE SLSSVVVQHA DASRAVSEVP
1090 1100 1110 1120 1130 1140
KRLQDVYSSE EENRVLSSHL ITHGFPQHSL QRQEHFTPLQ EETHIQRLIL GARKNNEEFA
1150 1160 1170 1180 1190 1200
PKQNELEKGL CSQQTDALSS PSQVTDWGTS RGSVSVRSDR TDPLRHFKIP AFRERLVRVS
1210 1220 1230 1240 1250 1260
QHTFPLQDNL QEHQEWVDTE KESFQSSPLT PENPSSQQTG FSSFKASLRL PSCVSLPSAD
1270 1280 1290 1300 1310 1320
SGITQHPLST ESDSKVKSSH LQIPELQHRL SKISQLIPPQ QDSLKALQEQ LATQREAIIH
1330 1340 1350 1360 1370 1380
SRQEAHEETL REWKEKIFPE QVGPFSPLIP QHSLASFPVS DTERAQELCS TNSDTISSGY
1390 1400 1410 1420 1430 1440
PEMLELPDRT LGLSHTALPQ QNNLTAHPEH LHAQTNFFHS TEKAQEGLVF PRPCQFEEMS
1450 1460 1470 1480 1490 1500
AEHFIQPQHD DLKALQQQLD MQREAIRSGQ EMQEKMLLQR LNKLEQRISS KQISSSLFSS
1510 1520 1530 1540 1550 1560
QVALPIANSD GTLQSFPTKS NETELLGSQD EYLSFSQPRL PLQNNMTEQL DLEKVFHKEL
1570 1580 1590 1600 1610 1620
LLHKQKSQNK SESSEHSLPP LFLSKEIEHP FISLPFAESK SKSICELYLS DKKHAAPNDA
1630 1640 1650 1660 1670 1680
VIPRLQDRLL SCSQPVLTQQ DNMSLQKQLN LQRETLHSRQ KAQEELLVQR QTSLQQQIQR
1690 1700 1710 1720 1730 1740
HRETLKNFFN VSQARNPTDE NDLEMQKREQ LGGWFPHTQG LTWGDAGQGS ANGEQPRADV
1750 1760 1770 1780 1790 1800
HAEHNGESLA KELSGRASKP PVSKVKCVLD LNQHELSTIQ EVESPASGRI SMPGKAEFYQ
1810 1820 1830 1840 1850 1860
DRDPLRVSVS REQSFLESPL AHDPFGCHQP PAQENSKSHD DNAEAVKVKK SDVEDHAVLS
1870 1880 1890 1900 1910 1920
HAVSKEEACT NLGPLGKPDD EAETQEISQE PLSSVTVSTG SFLSYEITDL SLTDPESFSE
1930 1940 1950 1960 1970 1980
QTEHLEQEST NKQEETDPLS IAVPSVIYQQ QHSLGAHNSL LPMEEESTSD HTHVQQIMDN
1990 2000 2010 2020 2030 2040
DVNEANLIPD KRDFQVPAVD LDFRELEHIF PHLHRQLFKP LEPHLDFDLS SPGTSQEDSD
2050 2060 2070 2080 2090 2100
FYQSSESSSE KHVKALSTGT ICFPALTAKS HSPNPRLNQL DINLAHATTE GSEQSFQQLR
2110 2120 2130 2140 2150 2160
PEFSSQESQH ADLPSIYSIE ARGPSQRMEN QNYSEMLQNK KKSLSLQPST EDLTPACSSS
2170 2180 2190 2200 2210 2220
DTALFDQLHL QHSTPCASVS SECSVKLLES REEVLGFEEL SRRAVTMSQR LTEDENVVLP
2230 2240 2250 2260 2270 2280
INPHVGRVEK EASVQGSNPL SIQNEKPIQN FIETDTTEAV GNVCQLAQAE HILKSCPFRS
2290 2300 2310 2320 2330 2340
PIPIWETDTG YGIMEEPDLT LVSNSDISIT ETDLANLTLE DREDNEAQFF QAGVVLPTSS
2350 2360 2370 2380 2390 2400
METSVCGAVS EPYVDQPTVA PSATSGSLQE AFMTRQTLTE RSYQRQREIW NKTRLPQTKV
2410
SKEKLPTGCT GS
10 20 30 40 50 60
MKRKGMNTKL RLSPSEEAFI LKEDYERRRK LRLLQVREQE RGIAFQIREG IKQRRSQQVS
70 80 90 100 110 120
HLAEELRAKW EEAQSQKIQN LEKLYLASLR HMGDGHRQAK ENEPDLDALS RRAAERKRKA
130 140 150 160 170 180
EVRHKEALKV QKNQKEMLMK QKTRHIKARK EAVLVEKQRS AKMARLPPPV PSPFENIDVN
190 200 210 220 230 240
RIPSLKTNSS TYHHISTFVS RQMGTKQPDA HLAAEEEARR VERLRKQAAQ ERVKQFERAH
250 260 270 280 290 300
VRGSQAMKKI HLAQNQERLM EELKQLQKED LARRRQTVAQ MPPQMLELPY RRSEMKEDRQ
310 320 330 340 350 360
RELEFAFEDM YNADRKVKGN LILHLKPEPL PTISDQLQDE ELDLSMEQEN QVPLAAKIQQ
370 380 390 400 410 420
IPSRILFKRL LNKIRSQKSL WTIKSVSEDE GEVTSSIIEI ESKVPSVDSG AIITEERTAA
430 440 450 460 470 480
SFEQEQVTDS DRLTIESGPL SSEDKPLYYK AGTGREQAMA VSPPATAVAQ SSVLLHPQEE
490 500 510 520 530 540
AVRIRMSLRR KQIMEIEEQK QKQLELLEQI EQQKLRLETD CFRAQLEEQR KQADQPEVCC
550 560 570 580 590 600
APMSHAMISD EDSHRQMIRN YQHQLLQQNR LHKETVETAR KRLLEYQTVL KERSPSLSAS
610 620 630 640 650 660
ALVPDSVVSG PPQQSYKPAA ASDSWDPSQR LKLSPSKYQP VQPSQIPALE QSHIQVPRHG
670 680 690 700 710 720
HITQRQGKMA VSEMLGKQPV ESQERQWQFS QVETHQGDYE FVLKDSHSLS RTLSYVRPQT
730 740 750 760 770 780
LQDAREVSKP PRVIICQSLD SQQISSEDSE NISSKPSEPS PFLPLVPERP FTSLPVKFHS
790 800 810 820 830 840
GTIHKPFTTI NQSVISQMHD QPLSSSETIT AQQGDLRFLQ EQLELQKKVL QARQEAREKL
850 860 870 880 890 900
LLCTQKELGQ QTGLPVFLPS PAGNIFSSLP SASAESGNFQ TSSTKSDATV SSDNMDRLWD
910 920 930 940 950 960
SSQPISSQQT HLEFLQEQSS VETDNLQARR EAQEVLFAHT QNTLEKIVRS EQAGSSLPHQ
970 980 990 1000 1010 1020
VAQQSFSSLT LADTQSKKIQ KQPLPANKKG LLPSQSEVSK AQDGSSGFLQ QTLPLQNTLK
1030 1040 1050 1060 1070 1080
LLQEQLTRQR SMIPPRRDGQ ETLLLYKESC SEDSEAGPVE SLSSVVVQHA DASRAVSEVP
1090 1100 1110 1120 1130 1140
KRLQDVYSSE EENRVLSSHL ITHGFPQHSL QRQEHFTPLQ EETHIQRLIL GARKNNEEFA
1150 1160 1170 1180 1190 1200
PKQNELEKGL CSQQTDALSS PSQVTDWGTS RGSVSVRSDR TDPLRHFKIP AFRERLVRVS
1210 1220 1230 1240 1250 1260
QHTFPLQDNL QEHQEWVDTE KESFQSSPLT PENPSSQQTG FSSFKASLRL PSCVSLPSAD
1270 1280 1290 1300 1310 1320
SGITQHPLST ESDSKVKSSH LQIPELQHRL SKISQLIPPQ QDSLKALQEQ LATQREAIIH
1330 1340 1350 1360 1370 1380
SRQEAHEETL REWKEKIFPE QVGPFSPLIP QHSLASFPVS DTERAQELCS TNSDTISSGY
1390 1400 1410 1420 1430 1440
PEMLELPDRT LGLSHTALPQ QNNLTAHPEH LHAQTNFFHS TEKAQEGLVF PRPCQFEEMS
1450 1460 1470 1480 1490 1500
AEHFIQPQHD DLKALQQQLD MQREAIRSGQ EMQEKMLLQR LNKLEQRISS KQISSSLFSS
1510 1520 1530 1540 1550 1560
QVALPIANSD GTLQSFPTKS NETELLGSQD EYLSFSQPRL PLQNNMTEQL DLEKVFHKEL
1570 1580 1590 1600 1610 1620
LLHKQKSQNK SESSEHSLPP LFLSKEIEHP FISLPFAESK SKSICELYLS DKKHAAPNDA
1630 1640 1650 1660 1670 1680
VIPRLQDRLL SCSQPVLTQQ DNMSLQKQLN LQRETLHSRQ KAQEELLVQR QTSLQQQIQR
1690 1700 1710 1720 1730 1740
HRETLKNFFN VSQARNPTDE NDLEMQKREQ LGGWFPHTQG LTWGDAGQGS ANGEQPRADV
1750 1760 1770 1780 1790 1800
HAEHNGESLA KELSGRASKP PVSKVKCVLD LNQHELSTIQ EVESPASGRI SMPGKAEFYQ
1810 1820 1830 1840 1850 1860
DRDPLRVSVS REQSFLESPL AHDPFGCHQP PAQENSKSHD DNAEAVKVKK SDVEDHAVLS
1870 1880 1890 1900 1910 1920
HAVSKEEACT NLGPLGKPDD EAETQEISQE PLSSVTVSTG SFLSYEITDL SLTDPESFSE
1930 1940 1950 1960 1970 1980
QTEHLEQEST NKQEETDPLS IAVPSVIYQQ QHSLGAHNSL LPMEEESTSD HTHVQQIMDN
1990 2000 2010 2020 2030 2040
DVNEANLIPD KRDFQVPAVD LDFRELEHIF PHLHRQLFKP LEPHLDFDLS SPGTSQEDSD
2050 2060 2070 2080 2090 2100
FYQSSESSSE KHVKALSTGT ICFPALTAKS HSPNPRLNQL DINLAHATTE GSEQSFQQLR
2110 2120 2130 2140 2150 2160
PEFSSQESQH ADLPSIYSIE ARGPSQRMEN QNYSEMLQNK KKSLSLQPST EDLTPACSSS
2170 2180 2190 2200 2210 2220
DTALFDQLHL QHSTPCASVS SECSVKLLES REEVLGFEEL SRRAVTMSQR LTEDENVVLP
2230 2240 2250 2260 2270 2280
INPHVGRVEK EASVQGSNPL SIQNEKPIQN FIETDTTEAV GNVCQLAQAE HILKSCPFRS
2290 2300 2310 2320 2330 2340
PIPIWETDTG YGIMEEPDLT LVSNSDISIT ETDLANLTLE DREDNEAQFF QAGVVLPTSS
2350 2360 2370 2380 2390 2400
METSVCGAVS EPYVDQPTVA PSATSGSLQE AFMTRQTLTE RSYQRQREIW NKTRLPQTKV
2410
SKEKLPTGCT GS
10 20 30 40 50 60
MKRKGMNTKL RLSPSEEAFI LKEDYERRRK LRLLQVREQE RGIAFQIREG IKQRRSQQVS
70 80 90 100 110 120
HLAEELRAKW EEAQSQKIQN LEKLYLASLR HMGDGHRQAK ENEPDLDALS RRAAERKRKA
130 140 150 160 170 180
EVRHKEALKV QKNQKEMLMK QKTRHIKARK EAVLVEKQRS AKMARLPPPV PSPFENIDVN
190 200 210 220 230 240
RIPSLKTNSS TYHHISTFVS RQMGTKQPDA HLAAEEEARR VERLRKQAAQ ERVKQFERAH
250 260 270 280 290 300
VRGSQAMKKI HLAQNQERLM EELKQLQKED LARRRQTVAQ MPPQMLELPY RRSEMKEDRQ
310 320 330 340 350 360
RELEFAFEDM YNADRKVKGN LILHLKPEPL PTISDQLQDE ELDLSMEQEN QVPLAAKIQQ
370 380 390 400 410 420
IPSRILFKRL LNKIRSQKSL WTIKSVSEDE GEVTSSIIEI ESKVPSVDSG AIITEERTAA
430 440 450 460 470 480
SFEQEQVTDS DRLTIESGPL SSEDKPLYYK AGTGREQAMA VSPPATAVAQ SSVLLHPQEE
490 500 510 520 530 540
AVRIRMSLRR KQIMEIEEQK QKQLELLEQI EQQKLRLETD CFRAQLEEQR KQADQPEVCC
550 560 570 580 590 600
APMSHAMISD EDSHRQMIRN YQHQLLQQNR LHKETVETAR KRLLEYQTVL KERSPSLSAS
610 620 630 640 650 660
ALVPDSVVSG PPQQSYKPAA ASDSWDPSQR LKLSPSKYQP VQPSQIPALE QSHIQVPRHG
670 680 690 700 710 720
HITQRQGKMA VSEMLGKQPV ESQERQWQFS QVETHQGDYE FVLKDSHSLS RTLSYVRPQT
730 740 750 760 770 780
LQDAREVSKP PRVIICQSLD SQQISSEDSE NISSKPSEPS PFLPLVPERP FTSLPVKFHS
790 800 810 820 830 840
GTIHKPFTTI NQSVISQMHD QPLSSSETIT AQQGDLRFLQ EQLELQKKVL QARQEAREKL
850 860 870 880 890 900
LLCTQKELGQ QTGLPVFLPS PAGNIFSSLP SASAESGNFQ TSSTKSDATV SSDNMDRLWD
910 920 930 940 950 960
SSQPISSQQT HLEFLQEQSS VETDNLQARR EAQEVLFAHT QNTLEKIVRS EQAGSSLPHQ
970 980 990 1000 1010 1020
VAQQSFSSLT LADTQSKKIQ KQPLPANKKG LLPSQSEVSK AQDGSSGFLQ QTLPLQNTLK
1030 1040 1050 1060 1070 1080
LLQEQLTRQR SMIPPRRDGQ ETLLLYKESC SEDSEAGPVE SLSSVVVQHA DASRAVSEVP
1090 1100 1110 1120 1130 1140
KRLQDVYSSE EENRVLSSHL ITHGFPQHSL QRQEHFTPLQ EETHIQRLIL GARKNNEEFA
1150 1160 1170 1180 1190 1200
PKQNELEKGL CSQQTDALSS PSQVTDWGTS RGSVSVRSDR TDPLRHFKIP AFRERLVRVS
1210 1220 1230 1240 1250 1260
QHTFPLQDNL QEHQEWVDTE KESFQSSPLT PENPSSQQTG FSSFKASLRL PSCVSLPSAD
1270 1280 1290 1300 1310 1320
SGITQHPLST ESDSKVKSSH LQIPELQHRL SKISQLIPPQ QDSLKALQEQ LATQREAIIH
1330 1340 1350 1360 1370 1380
SRQEAHEETL REWKEKIFPE QVGPFSPLIP QHSLASFPVS DTERAQELCS TNSDTISSGY
1390 1400 1410 1420 1430 1440
PEMLELPDRT LGLSHTALPQ QNNLTAHPEH LHAQTNFFHS TEKAQEGLVF PRPCQFEEMS
1450 1460 1470 1480 1490 1500
AEHFIQPQHD DLKALQQQLD MQREAIRSGQ EMQEKMLLQR LNKLEQRISS KQISSSLFSS
1510 1520 1530 1540 1550 1560
QVALPIANSD GTLQSFPTKS NETELLGSQD EYLSFSQPRL PLQNNMTEQL DLEKVFHKEL
1570 1580 1590 1600 1610 1620
LLHKQKSQNK SESSEHSLPP LFLSKEIEHP FISLPFAESK SKSICELYLS DKKHAAPNDA
1630 1640 1650 1660 1670 1680
VIPRLQDRLL SCSQPVLTQQ DNMSLQKQLN LQRETLHSRQ KAQEELLVQR QTSLQQQIQR
1690 1700 1710 1720 1730 1740
HRETLKNFFN VSQARNPTDE NDLEMQKREQ LGGWFPHTQG LTWGDAGQGS ANGEQPRADV
1750 1760 1770 1780 1790 1800
HAEHNGESLA KELSGRASKP PVSKVKCVLD LNQHELSTIQ EVESPASGRI SMPGKAEFYQ
1810 1820 1830 1840 1850 1860
DRDPLRVSVS REQSFLESPL AHDPFGCHQP PAQENSKSHD DNAEAVKVKK SDVEDHAVLS
1870 1880 1890 1900 1910 1920
HAVSKEEACT NLGPLGKPDD EAETQEISQE PLSSVTVSTG SFLSYEITDL SLTDPESFSE
1930 1940 1950 1960 1970 1980
QTEHLEQEST NKQEETDPLS IAVPSVIYQQ QHSLGAHNSL LPMEEESTSD HTHVQQIMDN
1990 2000 2010 2020 2030 2040
DVNEANLIPD KRDFQVPAVD LDFRELEHIF PHLHRQLFKP LEPHLDFDLS SPGTSQEDSD
2050 2060 2070 2080 2090 2100
FYQSSESSSE KHVKALSTGT ICFPALTAKS HSPNPRLNQL DINLAHATTE GSEQSFQQLR
2110 2120 2130 2140 2150 2160
PEFSSQESQH ADLPSIYSIE ARGPSQRMEN QNYSEMLQNK KKSLSLQPST EDLTPACSSS
2170 2180 2190 2200 2210 2220
DTALFDQLHL QHSTPCASVS SECSVKLLES REEVLGFEEL SRRAVTMSQR LTEDENVVLP
2230 2240 2250 2260 2270 2280
INPHVGRVEK EASVQGSNPL SIQNEKPIQN FIETDTTEAV GNVCQLAQAE HILKSCPFRS
2290 2300 2310 2320 2330 2340
PIPIWETDTG YGIMEEPDLT LVSNSDISIT ETDLANLTLE DREDNEAQFF QAGVVLPTSS
2350 2360 2370 2380 2390 2400
METSVCGAVS EPYVDQPTVA PSATSGSLQE AFMTRQTLTE RSYQRQREIW NKTRLPQTKV
2410
SKEKLPTGCT GS
10 20 30 40 50 60
MKRKGMNTKL RLSPSEEAFI LKEDYERRRK LRLLQVREQE RGIAFQIREG IKQRRSQQVS
70 80 90 100 110 120
HLAEELRAKW EEAQSQKIQN LEKLYLASLR HMGDGHRQAK ENEPDLDALS RRAAERKRKA
130 140 150 160 170 180
EVRHKEALKV QKNQKEMLMK QKTRHIKARK EAVLVEKQRS AKMARLPPPV PSPFENIDVN
190 200 210 220 230 240
RIPSLKTNSS TYHHISTFVS RQMGTKQPDA HLAAEEEARR VERLRKQAAQ ERVKQFERAH
250 260 270 280 290 300
VRGSQAMKKI HLAQNQERLM EELKQLQKED LARRRQTVAQ MPPQMLELPY RRSEMKEDRQ
310 320 330 340 350 360
RELEFAFEDM YNADRKVKGN LILHLKPEPL PTISDQLQDE ELDLSMEQEN QVPLAAKIQQ
370 380 390 400 410 420
IPSRILFKRL LNKIRSQKSL WTIKSVSEDE GEVTSSIIEI ESKVPSVDSG AIITEERTAA
430 440 450 460 470 480
SFEQEQVTDS DRLTIESGPL SSEDKPLYYK AGTGREQAMA VSPPATAVAQ SSVLLHPQEE
490 500 510 520 530 540
AVRIRMSLRR KQIMEIEEQK QKQLELLEQI EQQKLRLETD CFRAQLEEQR KQADQPEVCC
550 560 570 580 590 600
APMSHAMISD EDSHRQMIRN YQHQLLQQNR LHKETVETAR KRLLEYQTVL KERSPSLSAS
610 620 630 640 650 660
ALVPDSVVSG PPQQSYKPAA ASDSWDPSQR LKLSPSKYQP VQPSQIPALE QSHIQVPRHG
670 680 690 700 710 720
HITQRQGKMA VSEMLGKQPV ESQERQWQFS QVETHQGDYE FVLKDSHSLS RTLSYVRPQT
730 740 750 760 770 780
LQDAREVSKP PRVIICQSLD SQQISSEDSE NISSKPSEPS PFLPLVPERP FTSLPVKFHS
790 800 810 820 830 840
GTIHKPFTTI NQSVISQMHD QPLSSSETIT AQQGDLRFLQ EQLELQKKVL QARQEAREKL
850 860 870 880 890 900
LLCTQKELGQ QTGLPVFLPS PAGNIFSSLP SASAESGNFQ TSSTKSDATV SSDNMDRLWD
910 920 930 940 950 960
SSQPISSQQT HLEFLQEQSS VETDNLQARR EAQEVLFAHT QNTLEKIVRS EQAGSSLPHQ
970 980 990 1000 1010 1020
VAQQSFSSLT LADTQSKKIQ KQPLPANKKG LLPSQSEVSK AQDGSSGFLQ QTLPLQNTLK
1030 1040 1050 1060 1070 1080
LLQEQLTRQR SMIPPRRDGQ ETLLLYKESC SEDSEAGPVE SLSSVVVQHA DASRAVSEVP
1090 1100 1110 1120 1130 1140
KRLQDVYSSE EENRVLSSHL ITHGFPQHSL QRQEHFTPLQ EETHIQRLIL GARKNNEEFA
1150 1160 1170 1180 1190 1200
PKQNELEKGL CSQQTDALSS PSQVTDWGTS RGSVSVRSDR TDPLRHFKIP AFRERLVRVS
1210 1220 1230 1240 1250 1260
QHTFPLQDNL QEHQEWVDTE KESFQSSPLT PENPSSQQTG FSSFKASLRL PSCVSLPSAD
1270 1280 1290 1300 1310 1320
SGITQHPLST ESDSKVKSSH LQIPELQHRL SKISQLIPPQ QDSLKALQEQ LATQREAIIH
1330 1340 1350 1360 1370 1380
SRQEAHEETL REWKEKIFPE QVGPFSPLIP QHSLASFPVS DTERAQELCS TNSDTISSGY
1390 1400 1410 1420 1430 1440
PEMLELPDRT LGLSHTALPQ QNNLTAHPEH LHAQTNFFHS TEKAQEGLVF PRPCQFEEMS
1450 1460 1470 1480 1490 1500
AEHFIQPQHD DLKALQQQLD MQREAIRSGQ EMQEKMLLQR LNKLEQRISS KQISSSLFSS
1510 1520 1530 1540 1550 1560
QVALPIANSD GTLQSFPTKS NETELLGSQD EYLSFSQPRL PLQNNMTEQL DLEKVFHKEL
1570 1580 1590 1600 1610 1620
LLHKQKSQNK SESSEHSLPP LFLSKEIEHP FISLPFAESK SKSICELYLS DKKHAAPNDA
1630 1640 1650 1660 1670 1680
VIPRLQDRLL SCSQPVLTQQ DNMSLQKQLN LQRETLHSRQ KAQEELLVQR QTSLQQQIQR
1690 1700 1710 1720 1730 1740
HRETLKNFFN VSQARNPTDE NDLEMQKREQ LGGWFPHTQG LTWGDAGQGS ANGEQPRADV
1750 1760 1770 1780 1790 1800
HAEHNGESLA KELSGRASKP PVSKVKCVLD LNQHELSTIQ EVESPASGRI SMPGKAEFYQ
1810 1820 1830 1840 1850 1860
DRDPLRVSVS REQSFLESPL AHDPFGCHQP PAQENSKSHD DNAEAVKVKK SDVEDHAVLS
1870 1880 1890 1900 1910 1920
HAVSKEEACT NLGPLGKPDD EAETQEISQE PLSSVTVSTG SFLSYEITDL SLTDPESFSE
1930 1940 1950 1960 1970 1980
QTEHLEQEST NKQEETDPLS IAVPSVIYQQ QHSLGAHNSL LPMEEESTSD HTHVQQIMDN
1990 2000 2010 2020 2030 2040
DVNEANLIPD KRDFQVPAVD LDFRELEHIF PHLHRQLFKP LEPHLDFDLS SPGTSQEDSD
2050 2060 2070 2080 2090 2100
FYQSSESSSE KHVKALSTGT ICFPALTAKS HSPNPRLNQL DINLAHATTE GSEQSFQQLR
2110 2120 2130 2140 2150 2160
PEFSSQESQH ADLPSIYSIE ARGPSQRMEN QNYSEMLQNK KKSLSLQPST EDLTPACSSS
2170 2180 2190 2200 2210 2220
DTALFDQLHL QHSTPCASVS SECSVKLLES REEVLGFEEL SRRAVTMSQR LTEDENVVLP
2230 2240 2250 2260 2270 2280
INPHVGRVEK EASVQGSNPL SIQNEKPIQN FIETDTTEAV GNVCQLAQAE HILKSCPFRS
2290 2300 2310 2320 2330 2340
PIPIWETDTG YGIMEEPDLT LVSNSDISIT ETDLANLTLE DREDNEAQFF QAGVVLPTSS
2350 2360 2370 2380 2390 2400
METSVCGAVS EPYVDQPTVA PSATSGSLQE AFMTRQTLTE RSYQRQREIW NKTRLPQTKV
2410
SKEKLPTGCT GS
10 20 30 40 50 60
MKRKGMNTKL RLSPSEEAFI LKEDYERRRK LRLLQVREQE RGIAFQIREG IKQRRSQQVS
70 80 90 100 110 120
HLAEELRAKW EEAQSQKIQN LEKLYLASLR HMGDGHRQAK ENEPDLDALS RRAAERKRKA
130 140 150 160 170 180
EVRHKEALKV QKNQKEMLMK QKTRHIKARK EAVLVEKQRS AKMARLPPPV PSPFENIDVN
190 200 210 220 230 240
RIPSLKTNSS TYHHISTFVS RQMGTKQPDA HLAAEEEARR VERLRKQAAQ ERVKQFERAH
250 260 270 280 290 300
VRGSQAMKKI HLAQNQERLM EELKQLQKED LARRRQTVAQ MPPQMLELPY RRSEMKEDRQ
310 320 330 340 350 360
RELEFAFEDM YNADRKVKGN LILHLKPEPL PTISDQLQDE ELDLSMEQEN QVPLAAKIQQ
370 380 390 400 410 420
IPSRILFKRL LNKIRSQKSL WTIKSVSEDE GEVTSSIIEI ESKVPSVDSG AIITEERTAA
430 440 450 460 470 480
SFEQEQVTDS DRLTIESGPL SSEDKPLYYK AGTGREQAMA VSPPATAVAQ SSVLLHPQEE
490 500 510 520 530 540
AVRIRMSLRR KQIMEIEEQK QKQLELLEQI EQQKLRLETD CFRAQLEEQR KQADQPEVCC
550 560 570 580 590 600
APMSHAMISD EDSHRQMIRN YQHQLLQQNR LHKETVETAR KRLLEYQTVL KERSPSLSAS
610 620 630 640 650 660
ALVPDSVVSG PPQQSYKPAA ASDSWDPSQR LKLSPSKYQP VQPSQIPALE QSHIQVPRHG
670 680 690 700 710 720
HITQRQGKMA VSEMLGKQPV ESQERQWQFS QVETHQGDYE FVLKDSHSLS RTLSYVRPQT
730 740 750 760 770 780
LQDAREVSKP PRVIICQSLD SQQISSEDSE NISSKPSEPS PFLPLVPERP FTSLPVKFHS
790 800 810 820 830 840
GTIHKPFTTI NQSVISQMHD QPLSSSETIT AQQGDLRFLQ EQLELQKKVL QARQEAREKL
850 860 870 880 890 900
LLCTQKELGQ QTGLPVFLPS PAGNIFSSLP SASAESGNFQ TSSTKSDATV SSDNMDRLWD
910 920 930 940 950 960
SSQPISSQQT HLEFLQEQSS VETDNLQARR EAQEVLFAHT QNTLEKIVRS EQAGSSLPHQ
970 980 990 1000 1010 1020
VAQQSFSSLT LADTQSKKIQ KQPLPANKKG LLPSQSEVSK AQDGSSGFLQ QTLPLQNTLK
1030 1040 1050 1060 1070 1080
LLQEQLTRQR SMIPPRRDGQ ETLLLYKESC SEDSEAGPVE SLSSVVVQHA DASRAVSEVP
1090 1100 1110 1120 1130 1140
KRLQDVYSSE EENRVLSSHL ITHGFPQHSL QRQEHFTPLQ EETHIQRLIL GARKNNEEFA
1150 1160 1170 1180 1190 1200
PKQNELEKGL CSQQTDALSS PSQVTDWGTS RGSVSVRSDR TDPLRHFKIP AFRERLVRVS
1210 1220 1230 1240 1250 1260
QHTFPLQDNL QEHQEWVDTE KESFQSSPLT PENPSSQQTG FSSFKASLRL PSCVSLPSAD
1270 1280 1290 1300 1310 1320
SGITQHPLST ESDSKVKSSH LQIPELQHRL SKISQLIPPQ QDSLKALQEQ LATQREAIIH
1330 1340 1350 1360 1370 1380
SRQEAHEETL REWKEKIFPE QVGPFSPLIP QHSLASFPVS DTERAQELCS TNSDTISSGY
1390 1400 1410 1420 1430 1440
PEMLELPDRT LGLSHTALPQ QNNLTAHPEH LHAQTNFFHS TEKAQEGLVF PRPCQFEEMS
1450 1460 1470 1480 1490 1500
AEHFIQPQHD DLKALQQQLD MQREAIRSGQ EMQEKMLLQR LNKLEQRISS KQISSSLFSS
1510 1520 1530 1540 1550 1560
QVALPIANSD GTLQSFPTKS NETELLGSQD EYLSFSQPRL PLQNNMTEQL DLEKVFHKEL
1570 1580 1590 1600 1610 1620
LLHKQKSQNK SESSEHSLPP LFLSKEIEHP FISLPFAESK SKSICELYLS DKKHAAPNDA
1630 1640 1650 1660 1670 1680
VIPRLQDRLL SCSQPVLTQQ DNMSLQKQLN LQRETLHSRQ KAQEELLVQR QTSLQQQIQR
1690 1700 1710 1720 1730 1740
HRETLKNFFN VSQARNPTDE NDLEMQKREQ LGGWFPHTQG LTWGDAGQGS ANGEQPRADV
1750 1760 1770 1780 1790 1800
HAEHNGESLA KELSGRASKP PVSKVKCVLD LNQHELSTIQ EVESPASGRI SMPGKAEFYQ
1810 1820 1830 1840 1850 1860
DRDPLRVSVS REQSFLESPL AHDPFGCHQP PAQENSKSHD DNAEAVKVKK SDVEDHAVLS
1870 1880 1890 1900 1910 1920
HAVSKEEACT NLGPLGKPDD EAETQEISQE PLSSVTVSTG SFLSYEITDL SLTDPESFSE
1930 1940 1950 1960 1970 1980
QTEHLEQEST NKQEETDPLS IAVPSVIYQQ QHSLGAHNSL LPMEEESTSD HTHVQQIMDN
1990 2000 2010 2020 2030 2040
DVNEANLIPD KRDFQVPAVD LDFRELEHIF PHLHRQLFKP LEPHLDFDLS SPGTSQEDSD
2050 2060 2070 2080 2090 2100
FYQSSESSSE KHVKALSTGT ICFPALTAKS HSPNPRLNQL DINLAHATTE GSEQSFQQLR
2110 2120 2130 2140 2150 2160
PEFSSQESQH ADLPSIYSIE ARGPSQRMEN QNYSEMLQNK KKSLSLQPST EDLTPACSSS
2170 2180 2190 2200 2210 2220
DTALFDQLHL QHSTPCASVS SECSVKLLES REEVLGFEEL SRRAVTMSQR LTEDENVVLP
2230 2240 2250 2260 2270 2280
INPHVGRVEK EASVQGSNPL SIQNEKPIQN FIETDTTEAV GNVCQLAQAE HILKSCPFRS
2290 2300 2310 2320 2330 2340
PIPIWETDTG YGIMEEPDLT LVSNSDISIT ETDLANLTLE DREDNEAQFF QAGVVLPTSS
2350 2360 2370 2380 2390 2400
METSVCGAVS EPYVDQPTVA PSATSGSLQE AFMTRQTLTE RSYQRQREIW NKTRLPQTKV
2410
SKEKLPTGCT GS
10 20 30 40 50 60
MKRKGMNTKL RLSPSEEAFI LKEDYERRRK LRLLQVREQE RGIAFQIREG IKQRRSQQVS
70 80 90 100 110 120
HLAEELRAKW EEAQSQKIQN LEKLYLASLR HMGDGHRQAK ENEPDLDALS RRAAERKRKA
130 140 150 160 170 180
EVRHKEALKV QKNQKEMLMK QKTRHIKARK EAVLVEKQRS AKMARLPPPV PSPFENIDVN
190 200 210 220 230 240
RIPSLKTNSS TYHHISTFVS RQMGTKQPDA HLAAEEEARR VERLRKQAAQ ERVKQFERAH
250 260 270 280 290 300
VRGSQAMKKI HLAQNQERLM EELKQLQKED LARRRQTVAQ MPPQMLELPY RRSEMKEDRQ
310 320 330 340 350 360
RELEFAFEDM YNADRKVKGN LILHLKPEPL PTISDQLQDE ELDLSMEQEN QVPLAAKIQQ
370 380 390 400 410 420
IPSRILFKRL LNKIRSQKSL WTIKSVSEDE GEVTSSIIEI ESKVPSVDSG AIITEERTAA
430 440 450 460 470 480
SFEQEQVTDS DRLTIESGPL SSEDKPLYYK AGTGREQAMA VSPPATAVAQ SSVLLHPQEE
490 500 510 520 530 540
AVRIRMSLRR KQIMEIEEQK QKQLELLEQI EQQKLRLETD CFRAQLEEQR KQADQPEVCC
550 560 570 580 590 600
APMSHAMISD EDSHRQMIRN YQHQLLQQNR LHKETVETAR KRLLEYQTVL KERSPSLSAS
610 620 630 640 650 660
ALVPDSVVSG PPQQSYKPAA ASDSWDPSQR LKLSPSKYQP VQPSQIPALE QSHIQVPRHG
670 680 690 700 710 720
HITQRQGKMA VSEMLGKQPV ESQERQWQFS QVETHQGDYE FVLKDSHSLS RTLSYVRPQT
730 740 750 760 770 780
LQDAREVSKP PRVIICQSLD SQQISSEDSE NISSKPSEPS PFLPLVPERP FTSLPVKFHS
790 800 810 820 830 840
GTIHKPFTTI NQSVISQMHD QPLSSSETIT AQQGDLRFLQ EQLELQKKVL QARQEAREKL
850 860 870 880 890 900
LLCTQKELGQ QTGLPVFLPS PAGNIFSSLP SASAESGNFQ TSSTKSDATV SSDNMDRLWD
910 920 930 940 950 960
SSQPISSQQT HLEFLQEQSS VETDNLQARR EAQEVLFAHT QNTLEKIVRS EQAGSSLPHQ
970 980 990 1000 1010 1020
VAQQSFSSLT LADTQSKKIQ KQPLPANKKG LLPSQSEVSK AQDGSSGFLQ QTLPLQNTLK
1030 1040 1050 1060 1070 1080
LLQEQLTRQR SMIPPRRDGQ ETLLLYKESC SEDSEAGPVE SLSSVVVQHA DASRAVSEVP
1090 1100 1110 1120 1130 1140
KRLQDVYSSE EENRVLSSHL ITHGFPQHSL QRQEHFTPLQ EETHIQRLIL GARKNNEEFA
1150 1160 1170 1180 1190 1200
PKQNELEKGL CSQQTDALSS PSQVTDWGTS RGSVSVRSDR TDPLRHFKIP AFRERLVRVS
1210 1220 1230 1240 1250 1260
QHTFPLQDNL QEHQEWVDTE KESFQSSPLT PENPSSQQTG FSSFKASLRL PSCVSLPSAD
1270 1280 1290 1300 1310 1320
SGITQHPLST ESDSKVKSSH LQIPELQHRL SKISQLIPPQ QDSLKALQEQ LATQREAIIH
1330 1340 1350 1360 1370 1380
SRQEAHEETL REWKEKIFPE QVGPFSPLIP QHSLASFPVS DTERAQELCS TNSDTISSGY
1390 1400 1410 1420 1430 1440
PEMLELPDRT LGLSHTALPQ QNNLTAHPEH LHAQTNFFHS TEKAQEGLVF PRPCQFEEMS
1450 1460 1470 1480 1490 1500
AEHFIQPQHD DLKALQQQLD MQREAIRSGQ EMQEKMLLQR LNKLEQRISS KQISSSLFSS
1510 1520 1530 1540 1550 1560
QVALPIANSD GTLQSFPTKS NETELLGSQD EYLSFSQPRL PLQNNMTEQL DLEKVFHKEL
1570 1580 1590 1600 1610 1620
LLHKQKSQNK SESSEHSLPP LFLSKEIEHP FISLPFAESK SKSICELYLS DKKHAAPNDA
1630 1640 1650 1660 1670 1680
VIPRLQDRLL SCSQPVLTQQ DNMSLQKQLN LQRETLHSRQ KAQEELLVQR QTSLQQQIQR
1690 1700 1710 1720 1730 1740
HRETLKNFFN VSQARNPTDE NDLEMQKREQ LGGWFPHTQG LTWGDAGQGS ANGEQPRADV
1750 1760 1770 1780 1790 1800
HAEHNGESLA KELSGRASKP PVSKVKCVLD LNQHELSTIQ EVESPASGRI SMPGKAEFYQ
1810 1820 1830 1840 1850 1860
DRDPLRVSVS REQSFLESPL AHDPFGCHQP PAQENSKSHD DNAEAVKVKK SDVEDHAVLS
1870 1880 1890 1900 1910 1920
HAVSKEEACT NLGPLGKPDD EAETQEISQE PLSSVTVSTG SFLSYEITDL SLTDPESFSE
1930 1940 1950 1960 1970 1980
QTEHLEQEST NKQEETDPLS IAVPSVIYQQ QHSLGAHNSL LPMEEESTSD HTHVQQIMDN
1990 2000 2010 2020 2030 2040
DVNEANLIPD KRDFQVPAVD LDFRELEHIF PHLHRQLFKP LEPHLDFDLS SPGTSQEDSD
2050 2060 2070 2080 2090 2100
FYQSSESSSE KHVKALSTGT ICFPALTAKS HSPNPRLNQL DINLAHATTE GSEQSFQQLR
2110 2120 2130 2140 2150 2160
PEFSSQESQH ADLPSIYSIE ARGPSQRMEN QNYSEMLQNK KKSLSLQPST EDLTPACSSS
2170 2180 2190 2200 2210 2220
DTALFDQLHL QHSTPCASVS SECSVKLLES REEVLGFEEL SRRAVTMSQR LTEDENVVLP
2230 2240 2250 2260 2270 2280
INPHVGRVEK EASVQGSNPL SIQNEKPIQN FIETDTTEAV GNVCQLAQAE HILKSCPFRS
2290 2300 2310 2320 2330 2340
PIPIWETDTG YGIMEEPDLT LVSNSDISIT ETDLANLTLE DREDNEAQFF QAGVVLPTSS
2350 2360 2370 2380 2390 2400
METSVCGAVS EPYVDQPTVA PSATSGSLQE AFMTRQTLTE RSYQRQREIW NKTRLPQTKV
2410
SKEKLPTGCT GS
10 20 30 40 50 60
MKRKGMNTKL RLSPSEEAFI LKEDYERRRK LRLLQVREQE RGIAFQIREG IKQRRSQQVS
70 80 90 100 110 120
HLAEELRAKW EEAQSQKIQN LEKLYLASLR HMGDGHRQAK ENEPDLDALS RRAAERKRKA
130 140 150 160 170 180
EVRHKEALKV QKNQKEMLMK QKTRHIKARK EAVLVEKQRS AKMARLPPPV PSPFENIDVN
190 200 210 220 230 240
RIPSLKTNSS TYHHISTFVS RQMGTKQPDA HLAAEEEARR VERLRKQAAQ ERVKQFERAH
250 260 270 280 290 300
VRGSQAMKKI HLAQNQERLM EELKQLQKED LARRRQTVAQ MPPQMLELPY RRSEMKEDRQ
310 320 330 340 350 360
RELEFAFEDM YNADRKVKGN LILHLKPEPL PTISDQLQDE ELDLSMEQEN QVPLAAKIQQ
370 380 390 400 410 420
IPSRILFKRL LNKIRSQKSL WTIKSVSEDE GEVTSSIIEI ESKVPSVDSG AIITEERTAA
430 440 450 460 470 480
SFEQEQVTDS DRLTIESGPL SSEDKPLYYK AGTGREQAMA VSPPATAVAQ SSVLLHPQEE
490 500 510 520 530 540
AVRIRMSLRR KQIMEIEEQK QKQLELLEQI EQQKLRLETD CFRAQLEEQR KQADQPEVCC
550 560 570 580 590 600
APMSHAMISD EDSHRQMIRN YQHQLLQQNR LHKETVETAR KRLLEYQTVL KERSPSLSAS
610 620 630 640 650 660
ALVPDSVVSG PPQQSYKPAA ASDSWDPSQR LKLSPSKYQP VQPSQIPALE QSHIQVPRHG
670 680 690 700 710 720
HITQRQGKMA VSEMLGKQPV ESQERQWQFS QVETHQGDYE FVLKDSHSLS RTLSYVRPQT
730 740 750 760 770 780
LQDAREVSKP PRVIICQSLD SQQISSEDSE NISSKPSEPS PFLPLVPERP FTSLPVKFHS
790 800 810 820 830 840
GTIHKPFTTI NQSVISQMHD QPLSSSETIT AQQGDLRFLQ EQLELQKKVL QARQEAREKL
850 860 870 880 890 900
LLCTQKELGQ QTGLPVFLPS PAGNIFSSLP SASAESGNFQ TSSTKSDATV SSDNMDRLWD
910 920 930 940 950 960
SSQPISSQQT HLEFLQEQSS VETDNLQARR EAQEVLFAHT QNTLEKIVRS EQAGSSLPHQ
970 980 990 1000 1010 1020
VAQQSFSSLT LADTQSKKIQ KQPLPANKKG LLPSQSEVSK AQDGSSGFLQ QTLPLQNTLK
1030 1040 1050 1060 1070 1080
LLQEQLTRQR SMIPPRRDGQ ETLLLYKESC SEDSEAGPVE SLSSVVVQHA DASRAVSEVP
1090 1100 1110 1120 1130 1140
KRLQDVYSSE EENRVLSSHL ITHGFPQHSL QRQEHFTPLQ EETHIQRLIL GARKNNEEFA
1150 1160 1170 1180 1190 1200
PKQNELEKGL CSQQTDALSS PSQVTDWGTS RGSVSVRSDR TDPLRHFKIP AFRERLVRVS
1210 1220 1230 1240 1250 1260
QHTFPLQDNL QEHQEWVDTE KESFQSSPLT PENPSSQQTG FSSFKASLRL PSCVSLPSAD
1270 1280 1290 1300 1310 1320
SGITQHPLST ESDSKVKSSH LQIPELQHRL SKISQLIPPQ QDSLKALQEQ LATQREAIIH
1330 1340 1350 1360 1370 1380
SRQEAHEETL REWKEKIFPE QVGPFSPLIP QHSLASFPVS DTERAQELCS TNSDTISSGY
1390 1400 1410 1420 1430 1440
PEMLELPDRT LGLSHTALPQ QNNLTAHPEH LHAQTNFFHS TEKAQEGLVF PRPCQFEEMS
1450 1460 1470 1480 1490 1500
AEHFIQPQHD DLKALQQQLD MQREAIRSGQ EMQEKMLLQR LNKLEQRISS KQISSSLFSS
1510 1520 1530 1540 1550 1560
QVALPIANSD GTLQSFPTKS NETELLGSQD EYLSFSQPRL PLQNNMTEQL DLEKVFHKEL
1570 1580 1590 1600 1610 1620
LLHKQKSQNK SESSEHSLPP LFLSKEIEHP FISLPFAESK SKSICELYLS DKKHAAPNDA
1630 1640 1650 1660 1670 1680
VIPRLQDRLL SCSQPVLTQQ DNMSLQKQLN LQRETLHSRQ KAQEELLVQR QTSLQQQIQR
1690 1700 1710 1720 1730 1740
HRETLKNFFN VSQARNPTDE NDLEMQKREQ LGGWFPHTQG LTWGDAGQGS ANGEQPRADV
1750 1760 1770 1780 1790 1800
HAEHNGESLA KELSGRASKP PVSKVKCVLD LNQHELSTIQ EVESPASGRI SMPGKAEFYQ
1810 1820 1830 1840 1850 1860
DRDPLRVSVS REQSFLESPL AHDPFGCHQP PAQENSKSHD DNAEAVKVKK SDVEDHAVLS
1870 1880 1890 1900 1910 1920
HAVSKEEACT NLGPLGKPDD EAETQEISQE PLSSVTVSTG SFLSYEITDL SLTDPESFSE
1930 1940 1950 1960 1970 1980
QTEHLEQEST NKQEETDPLS IAVPSVIYQQ QHSLGAHNSL LPMEEESTSD HTHVQQIMDN
1990 2000 2010 2020 2030 2040
DVNEANLIPD KRDFQVPAVD LDFRELEHIF PHLHRQLFKP LEPHLDFDLS SPGTSQEDSD
2050 2060 2070 2080 2090 2100
FYQSSESSSE KHVKALSTGT ICFPALTAKS HSPNPRLNQL DINLAHATTE GSEQSFQQLR
2110 2120 2130 2140 2150 2160
PEFSSQESQH ADLPSIYSIE ARGPSQRMEN QNYSEMLQNK KKSLSLQPST EDLTPACSSS
2170 2180 2190 2200 2210 2220
DTALFDQLHL QHSTPCASVS SECSVKLLES REEVLGFEEL SRRAVTMSQR LTEDENVVLP
2230 2240 2250 2260 2270 2280
INPHVGRVEK EASVQGSNPL SIQNEKPIQN FIETDTTEAV GNVCQLAQAE HILKSCPFRS
2290 2300 2310 2320 2330 2340
PIPIWETDTG YGIMEEPDLT LVSNSDISIT ETDLANLTLE DREDNEAQFF QAGVVLPTSS
2350 2360 2370 2380 2390 2400
METSVCGAVS EPYVDQPTVA PSATSGSLQE AFMTRQTLTE RSYQRQREIW NKTRLPQTKV
2410
SKEKLPTGCT GS
10 20 30 40 50 60
MKRKGMNTKL RLSPSEEAFI LKEDYERRRK LRLLQVREQE RGIAFQIREG IKQRRSQQVS
70 80 90 100 110 120
HLAEELRAKW EEAQSQKIQN LEKLYLASLR HMGDGHRQAK ENEPDLDALS RRAAERKRKA
130 140 150 160 170 180
EVRHKEALKV QKNQKEMLMK QKTRHIKARK EAVLVEKQRS AKMARLPPPV PSPFENIDVN
190 200 210 220 230 240
RIPSLKTNSS TYHHISTFVS RQMGTKQPDA HLAAEEEARR VERLRKQAAQ ERVKQFERAH
250 260 270 280 290 300
VRGSQAMKKI HLAQNQERLM EELKQLQKED LARRRQTVAQ MPPQMLELPY RRSEMKEDRQ
310 320 330 340 350 360
RELEFAFEDM YNADRKVKGN LILHLKPEPL PTISDQLQDE ELDLSMEQEN QVPLAAKIQQ
370 380 390 400 410 420
IPSRILFKRL LNKIRSQKSL WTIKSVSEDE GEVTSSIIEI ESKVPSVDSG AIITEERTAA
430 440 450 460 470 480
SFEQEQVTDS DRLTIESGPL SSEDKPLYYK AGTGREQAMA VSPPATAVAQ SSVLLHPQEE
490 500 510 520 530 540
AVRIRMSLRR KQIMEIEEQK QKQLELLEQI EQQKLRLETD CFRAQLEEQR KQADQPEVCC
550 560 570 580 590 600
APMSHAMISD EDSHRQMIRN YQHQLLQQNR LHKETVETAR KRLLEYQTVL KERSPSLSAS
610 620 630 640 650 660
ALVPDSVVSG PPQQSYKPAA ASDSWDPSQR LKLSPSKYQP VQPSQIPALE QSHIQVPRHG
670 680 690 700 710 720
HITQRQGKMA VSEMLGKQPV ESQERQWQFS QVETHQGDYE FVLKDSHSLS RTLSYVRPQT
730 740 750 760 770 780
LQDAREVSKP PRVIICQSLD SQQISSEDSE NISSKPSEPS PFLPLVPERP FTSLPVKFHS
790 800 810 820 830 840
GTIHKPFTTI NQSVISQMHD QPLSSSETIT AQQGDLRFLQ EQLELQKKVL QARQEAREKL
850 860 870 880 890 900
LLCTQKELGQ QTGLPVFLPS PAGNIFSSLP SASAESGNFQ TSSTKSDATV SSDNMDRLWD
910 920 930 940 950 960
SSQPISSQQT HLEFLQEQSS VETDNLQARR EAQEVLFAHT QNTLEKIVRS EQAGSSLPHQ
970 980 990 1000 1010 1020
VAQQSFSSLT LADTQSKKIQ KQPLPANKKG LLPSQSEVSK AQDGSSGFLQ QTLPLQNTLK
1030 1040 1050 1060 1070 1080
LLQEQLTRQR SMIPPRRDGQ ETLLLYKESC SEDSEAGPVE SLSSVVVQHA DASRAVSEVP
1090 1100 1110 1120 1130 1140
KRLQDVYSSE EENRVLSSHL ITHGFPQHSL QRQEHFTPLQ EETHIQRLIL GARKNNEEFA
1150 1160 1170 1180 1190 1200
PKQNELEKGL CSQQTDALSS PSQVTDWGTS RGSVSVRSDR TDPLRHFKIP AFRERLVRVS
1210 1220 1230 1240 1250 1260
QHTFPLQDNL QEHQEWVDTE KESFQSSPLT PENPSSQQTG FSSFKASLRL PSCVSLPSAD
1270 1280 1290 1300 1310 1320
SGITQHPLST ESDSKVKSSH LQIPELQHRL SKISQLIPPQ QDSLKALQEQ LATQREAIIH
1330 1340 1350 1360 1370 1380
SRQEAHEETL REWKEKIFPE QVGPFSPLIP QHSLASFPVS DTERAQELCS TNSDTISSGY
1390 1400 1410 1420 1430 1440
PEMLELPDRT LGLSHTALPQ QNNLTAHPEH LHAQTNFFHS TEKAQEGLVF PRPCQFEEMS
1450 1460 1470 1480 1490 1500
AEHFIQPQHD DLKALQQQLD MQREAIRSGQ EMQEKMLLQR LNKLEQRISS KQISSSLFSS
1510 1520 1530 1540 1550 1560
QVALPIANSD GTLQSFPTKS NETELLGSQD EYLSFSQPRL PLQNNMTEQL DLEKVFHKEL
1570 1580 1590 1600 1610 1620
LLHKQKSQNK SESSEHSLPP LFLSKEIEHP FISLPFAESK SKSICELYLS DKKHAAPNDA
1630 1640 1650 1660 1670 1680
VIPRLQDRLL SCSQPVLTQQ DNMSLQKQLN LQRETLHSRQ KAQEELLVQR QTSLQQQIQR
1690 1700 1710 1720 1730 1740
HRETLKNFFN VSQARNPTDE NDLEMQKREQ LGGWFPHTQG LTWGDAGQGS ANGEQPRADV
1750 1760 1770 1780 1790 1800
HAEHNGESLA KELSGRASKP PVSKVKCVLD LNQHELSTIQ EVESPASGRI SMPGKAEFYQ
1810 1820 1830 1840 1850 1860
DRDPLRVSVS REQSFLESPL AHDPFGCHQP PAQENSKSHD DNAEAVKVKK SDVEDHAVLS
1870 1880 1890 1900 1910 1920
HAVSKEEACT NLGPLGKPDD EAETQEISQE PLSSVTVSTG SFLSYEITDL SLTDPESFSE
1930 1940 1950 1960 1970 1980
QTEHLEQEST NKQEETDPLS IAVPSVIYQQ QHSLGAHNSL LPMEEESTSD HTHVQQIMDN
1990 2000 2010 2020 2030 2040
DVNEANLIPD KRDFQVPAVD LDFRELEHIF PHLHRQLFKP LEPHLDFDLS SPGTSQEDSD
2050 2060 2070 2080 2090 2100
FYQSSESSSE KHVKALSTGT ICFPALTAKS HSPNPRLNQL DINLAHATTE GSEQSFQQLR
2110 2120 2130 2140 2150 2160
PEFSSQESQH ADLPSIYSIE ARGPSQRMEN QNYSEMLQNK KKSLSLQPST EDLTPACSSS
2170 2180 2190 2200 2210 2220
DTALFDQLHL QHSTPCASVS SECSVKLLES REEVLGFEEL SRRAVTMSQR LTEDENVVLP
2230 2240 2250 2260 2270 2280
INPHVGRVEK EASVQGSNPL SIQNEKPIQN FIETDTTEAV GNVCQLAQAE HILKSCPFRS
2290 2300 2310 2320 2330 2340
PIPIWETDTG YGIMEEPDLT LVSNSDISIT ETDLANLTLE DREDNEAQFF QAGVVLPTSS
2350 2360 2370 2380 2390 2400
METSVCGAVS EPYVDQPTVA PSATSGSLQE AFMTRQTLTE RSYQRQREIW NKTRLPQTKV
2410
SKEKLPTGCT GS
10 20 30 40 50 60
MKRKGMNTKL RLSPSEEAFI LKEDYERRRK LRLLQVREQE RGIAFQIREG IKQRRSQQVS
70 80 90 100 110 120
HLAEELRAKW EEAQSQKIQN LEKLYLASLR HMGDGHRQAK ENEPDLDALS RRAAERKRKA
130 140 150 160 170 180
EVRHKEALKV QKNQKEMLMK QKTRHIKARK EAVLVEKQRS AKMARLPPPV PSPFENIDVN
190 200 210 220 230 240
RIPSLKTNSS TYHHISTFVS RQMGTKQPDA HLAAEEEARR VERLRKQAAQ ERVKQFERAH
250 260 270 280 290 300
VRGSQAMKKI HLAQNQERLM EELKQLQKED LARRRQTVAQ MPPQMLELPY RRSEMKEDRQ
310 320 330 340 350 360
RELEFAFEDM YNADRKVKGN LILHLKPEPL PTISDQLQDE ELDLSMEQEN QVPLAAKIQQ
370 380 390 400 410 420
IPSRILFKRL LNKIRSQKSL WTIKSVSEDE GEVTSSIIEI ESKVPSVDSG AIITEERTAA
430 440 450 460 470 480
SFEQEQVTDS DRLTIESGPL SSEDKPLYYK AGTGREQAMA VSPPATAVAQ SSVLLHPQEE
490 500 510 520 530 540
AVRIRMSLRR KQIMEIEEQK QKQLELLEQI EQQKLRLETD CFRAQLEEQR KQADQPEVCC
550 560 570 580 590 600
APMSHAMISD EDSHRQMIRN YQHQLLQQNR LHKETVETAR KRLLEYQTVL KERSPSLSAS
610 620 630 640 650 660
ALVPDSVVSG PPQQSYKPAA ASDSWDPSQR LKLSPSKYQP VQPSQIPALE QSHIQVPRHG
670 680 690 700 710 720
HITQRQGKMA VSEMLGKQPV ESQERQWQFS QVETHQGDYE FVLKDSHSLS RTLSYVRPQT
730 740 750 760 770 780
LQDAREVSKP PRVIICQSLD SQQISSEDSE NISSKPSEPS PFLPLVPERP FTSLPVKFHS
790 800 810 820 830 840
GTIHKPFTTI NQSVISQMHD QPLSSSETIT AQQGDLRFLQ EQLELQKKVL QARQEAREKL
850 860 870 880 890 900
LLCTQKELGQ QTGLPVFLPS PAGNIFSSLP SASAESGNFQ TSSTKSDATV SSDNMDRLWD
910 920 930 940 950 960
SSQPISSQQT HLEFLQEQSS VETDNLQARR EAQEVLFAHT QNTLEKIVRS EQAGSSLPHQ
970 980 990 1000 1010 1020
VAQQSFSSLT LADTQSKKIQ KQPLPANKKG LLPSQSEVSK AQDGSSGFLQ QTLPLQNTLK
1030 1040 1050 1060 1070 1080
LLQEQLTRQR SMIPPRRDGQ ETLLLYKESC SEDSEAGPVE SLSSVVVQHA DASRAVSEVP
1090 1100 1110 1120 1130 1140
KRLQDVYSSE EENRVLSSHL ITHGFPQHSL QRQEHFTPLQ EETHIQRLIL GARKNNEEFA
1150 1160 1170 1180 1190 1200
PKQNELEKGL CSQQTDALSS PSQVTDWGTS RGSVSVRSDR TDPLRHFKIP AFRERLVRVS
1210 1220 1230 1240 1250 1260
QHTFPLQDNL QEHQEWVDTE KESFQSSPLT PENPSSQQTG FSSFKASLRL PSCVSLPSAD
1270 1280 1290 1300 1310 1320
SGITQHPLST ESDSKVKSSH LQIPELQHRL SKISQLIPPQ QDSLKALQEQ LATQREAIIH
1330 1340 1350 1360 1370 1380
SRQEAHEETL REWKEKIFPE QVGPFSPLIP QHSLASFPVS DTERAQELCS TNSDTISSGY
1390 1400 1410 1420 1430 1440
PEMLELPDRT LGLSHTALPQ QNNLTAHPEH LHAQTNFFHS TEKAQEGLVF PRPCQFEEMS
1450 1460 1470 1480 1490 1500
AEHFIQPQHD DLKALQQQLD MQREAIRSGQ EMQEKMLLQR LNKLEQRISS KQISSSLFSS
1510 1520 1530 1540 1550 1560
QVALPIANSD GTLQSFPTKS NETELLGSQD EYLSFSQPRL PLQNNMTEQL DLEKVFHKEL
1570 1580 1590 1600 1610 1620
LLHKQKSQNK SESSEHSLPP LFLSKEIEHP FISLPFAESK SKSICELYLS DKKHAAPNDA
1630 1640 1650 1660 1670 1680
VIPRLQDRLL SCSQPVLTQQ DNMSLQKQLN LQRETLHSRQ KAQEELLVQR QTSLQQQIQR
1690 1700 1710 1720 1730 1740
HRETLKNFFN VSQARNPTDE NDLEMQKREQ LGGWFPHTQG LTWGDAGQGS ANGEQPRADV
1750 1760 1770 1780 1790 1800
HAEHNGESLA KELSGRASKP PVSKVKCVLD LNQHELSTIQ EVESPASGRI SMPGKAEFYQ
1810 1820 1830 1840 1850 1860
DRDPLRVSVS REQSFLESPL AHDPFGCHQP PAQENSKSHD DNAEAVKVKK SDVEDHAVLS
1870 1880 1890 1900 1910 1920
HAVSKEEACT NLGPLGKPDD EAETQEISQE PLSSVTVSTG SFLSYEITDL SLTDPESFSE
1930 1940 1950 1960 1970 1980
QTEHLEQEST NKQEETDPLS IAVPSVIYQQ QHSLGAHNSL LPMEEESTSD HTHVQQIMDN
1990 2000 2010 2020 2030 2040
DVNEANLIPD KRDFQVPAVD LDFRELEHIF PHLHRQLFKP LEPHLDFDLS SPGTSQEDSD
2050 2060 2070 2080 2090 2100
FYQSSESSSE KHVKALSTGT ICFPALTAKS HSPNPRLNQL DINLAHATTE GSEQSFQQLR
2110 2120 2130 2140 2150 2160
PEFSSQESQH ADLPSIYSIE ARGPSQRMEN QNYSEMLQNK KKSLSLQPST EDLTPACSSS
2170 2180 2190 2200 2210 2220
DTALFDQLHL QHSTPCASVS SECSVKLLES REEVLGFEEL SRRAVTMSQR LTEDENVVLP
2230 2240 2250 2260 2270 2280
INPHVGRVEK EASVQGSNPL SIQNEKPIQN FIETDTTEAV GNVCQLAQAE HILKSCPFRS
2290 2300 2310 2320 2330 2340
PIPIWETDTG YGIMEEPDLT LVSNSDISIT ETDLANLTLE DREDNEAQFF QAGVVLPTSS
2350 2360 2370 2380 2390 2400
METSVCGAVS EPYVDQPTVA PSATSGSLQE AFMTRQTLTE RSYQRQREIW NKTRLPQTKV
2410
SKEKLPTGCT GS
Protein Neighborhood
Domains & Features
1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q8BQ48-1-unknown | MKRKGM... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q8BQ48-1-unknown | MKRKGM... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt78445 | |||
| Q8BQ48-1-unknown | MKRKGM... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt78446 | |||
| Q8BQ48-1-unknown | MKRKGM... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt78447 | |||
| Q8BQ48-1-unknown | MKRKGM... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt78448 | |||
| Q8BQ48-1-unknown | MKRKGM... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt78449 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...GCTGS | 2412 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...GCTGS | 2412 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt74065 | |||
| ...GCTGS | 2412 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt74064 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|