TopFIND 4.0

Q8BSK8: Ribosomal protein S6 kinase beta-1

General Information

Protein names
- Ribosomal protein S6 kinase beta-1
- S6K-beta-1
- S6K1
- 2.7.11.1 {ECO:0000269|PubMed:11500364}
- 70 kDa ribosomal protein S6 kinase 1
- P70S6K1
- p70-S6K 1
- Ribosomal protein S6 kinase I
- S6K
- p70 ribosomal S6 kinase alpha
- p70 S6 kinase alpha
- p70 S6K-alpha
- p70 S6KA
Gene names Rps6kb1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8BSK8

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRRRRRRDGF YLAPDFRHRE AEDMAGVFDI DLDQPEDAGS EDELEEGGQL NESMDHGGVG 
        70         80         90        100        110        120 
PYELGMEHCE KFEISETSVN RGPEKIRPEC FELLRVLGKG GYGKVFQVRK VTGANTGKIF 
       130        140        150        160        170        180 
AMKVLKKAMI VRNAKDTAHT KAERNILEEV KHPFIVDLIY AFQTGGKLYL ILEYLSGGEL 
       190        200        210        220        230        240 
FMQLEREGIF MEDTACFYLA EISMALGHLH QKGIIYRDLK PENIMLNHQG HVKLTDFGLC 
       250        260        270        280        290        300 
KESIHDGTVT HTFCGTIEYM APEILMRSGH NRAVDWWSLG ALMYDMLTGA PPFTGENRKK 
       310        320        330        340        350        360 
TIDKILKCKL NLPPYLTQEA RDLLKKLLKR NAASRLGAGP GDAGEVQAHP FFRHINWEEL 
       370        380        390        400        410        420 
LARKVEPPFK PLLQSEEDVS QFDSKFTRQT PVDSPDDSTL SESANQVFLG FTYVAPSVLE 
       430        440        450        460        470        480 
SVKEKFSFEP KIRSPRRFIG SPRTPVSPVK FSPGDFWGRG ASASTANPQT PVEYPMETSG 
       490        500        510        520    
IEQMDVTVSG EASAPLPIRQ PNSGPYKKQA FPMISKRPEH LRMNL

Isoforms

- Isoform Alpha II of Ribosomal protein S6 kinase beta-1

Sequence View

        10         20         30         40         50         60 
MRRRRRRDGF YLAPDFRHRE AEDMAGVFDI DLDQPEDAGS EDELEEGGQL NESMDHGGVG 
        70         80         90        100        110        120 
PYELGMEHCE KFEISETSVN RGPEKIRPEC FELLRVLGKG GYGKVFQVRK VTGANTGKIF 
       130        140        150        160        170        180 
AMKVLKKAMI VRNAKDTAHT KAERNILEEV KHPFIVDLIY AFQTGGKLYL ILEYLSGGEL 
       190        200        210        220        230        240 
FMQLEREGIF MEDTACFYLA EISMALGHLH QKGIIYRDLK PENIMLNHQG HVKLTDFGLC 
       250        260        270        280        290        300 
KESIHDGTVT HTFCGTIEYM APEILMRSGH NRAVDWWSLG ALMYDMLTGA PPFTGENRKK 
       310        320        330        340        350        360 
TIDKILKCKL NLPPYLTQEA RDLLKKLLKR NAASRLGAGP GDAGEVQAHP FFRHINWEEL 
       370        380        390        400        410        420 
LARKVEPPFK PLLQSEEDVS QFDSKFTRQT PVDSPDDSTL SESANQVFLG FTYVAPSVLE 
       430        440        450        460        470        480 
SVKEKFSFEP KIRSPRRFIG SPRTPVSPVK FSPGDFWGRG ASASTANPQT PVEYPMETSG 
       490        500        510        520    
IEQMDVTVSG EASAPLPIRQ PNSGPYKKQA FPMISKRPEH LRMNL



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Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8BSK8-1-unknown MRRRRR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8BSK8-24-unknown MAGVFD... 24 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt79264
    Q8BSK8-24-unknown MAGVFD... 24 inferred from electronic annotation unknown TISdb inferred from TISdb

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LRMNL 525 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LRMNL 525 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt74882

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)