TopFIND 4.0

Q8BT14: CCR4-NOT transcription complex subunit 4

General Information

Protein names
- CCR4-NOT transcription complex subunit 4
- 2.3.2.27 {ECO:0000250|UniProtKB:O95628}
- CCR4-associated factor 4
- E3 ubiquitin-protein ligase CNOT4
- Potential transcriptional repressor NOT4Hp
- RING-type E3 ubiquitin transferase CNOT4 {ECO:0000305}
Gene names Cnot4
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8BT14

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSRSPDAKED PVECPLCMEP LEIDDINFFP CTCGYQICRF CWHRIRTDEN GLCPACRKPY 
        70         80         90        100        110        120 
PEDPAVYKPL SQEELQRIKN EKKQKQNERK QKISENRKHL ASVRVVQKNL VFVVGLSQRL 
       130        140        150        160        170        180 
ADPEVLKRPE YFGKFGKIHK VVINNSTSYA GSQGPSASAY VTYIRSEDAL RAIQCVNNVV 
       190        200        210        220        230        240 
VDGRTLKASL GTTKYCSYFL KNMQCPKPDC MYLHELGDEA ASFTKEEMQA GKHQEYEQKL 
       250        260        270        280        290        300 
LQELYKLNPN FLQLSTGSVD KNKNKVTPLQ RYDTPIDKPS DSLSIGNGDN SQQISNSDTP 
       310        320        330        340        350        360 
SPPPGLSKSN PVIPISSSNH SARSPFEGAV TESQSLFSDN FRHPNPIPSG LPPFPSSPQT 
       370        380        390        400        410        420 
PSDWPTAPEP QSLFTSETIP VSSSTDWQAA FGFGSSKQPE DDLGFDPFDV TRKALADLIE 
       430        440        450        460        470        480 
KELSVQDQPS LSPTSLQNAS SHTTTAKGPG SGFLHSAAPT NANSLNSTFS VLPQRFPQFQ 
       490        500        510        520        530        540 
QHRAVYNSFG FPGQAARYPW MAFPRNSIMH LNHTANPTSN SNFLDLNLPP QHNTGLGGIP 
       550        560        570    
IAGEEEVKVS TMPLSASSHS LQQGQQPTSL HTTVA

Isoforms

- Isoform 2 of CCR4-NOT transcription complex subunit 4 - Isoform 3 of CCR4-NOT transcription complex subunit 4

Sequence View

        10         20         30         40         50         60 
MSRSPDAKED PVECPLCMEP LEIDDINFFP CTCGYQICRF CWHRIRTDEN GLCPACRKPY 
        70         80         90        100        110        120 
PEDPAVYKPL SQEELQRIKN EKKQKQNERK QKISENRKHL ASVRVVQKNL VFVVGLSQRL 
       130        140        150        160        170        180 
ADPEVLKRPE YFGKFGKIHK VVINNSTSYA GSQGPSASAY VTYIRSEDAL RAIQCVNNVV 
       190        200        210        220        230        240 
VDGRTLKASL GTTKYCSYFL KNMQCPKPDC MYLHELGDEA ASFTKEEMQA GKHQEYEQKL 
       250        260        270        280        290        300 
LQELYKLNPN FLQLSTGSVD KNKNKVTPLQ RYDTPIDKPS DSLSIGNGDN SQQISNSDTP 
       310        320        330        340        350        360 
SPPPGLSKSN PVIPISSSNH SARSPFEGAV TESQSLFSDN FRHPNPIPSG LPPFPSSPQT 
       370        380        390        400        410        420 
PSDWPTAPEP QSLFTSETIP VSSSTDWQAA FGFGSSKQPE DDLGFDPFDV TRKALADLIE 
       430        440        450        460        470        480 
KELSVQDQPS LSPTSLQNAS SHTTTAKGPG SGFLHSAAPT NANSLNSTFS VLPQRFPQFQ 
       490        500        510        520        530        540 
QHRAVYNSFG FPGQAARYPW MAFPRNSIMH LNHTANPTSN SNFLDLNLPP QHNTGLGGIP 
       550        560        570    
IAGEEEVKVS TMPLSASSHS LQQGQQPTSL HTTVA         10         20         30         40         50         60 
MSRSPDAKED PVECPLCMEP LEIDDINFFP CTCGYQICRF CWHRIRTDEN GLCPACRKPY 
        70         80         90        100        110        120 
PEDPAVYKPL SQEELQRIKN EKKQKQNERK QKISENRKHL ASVRVVQKNL VFVVGLSQRL 
       130        140        150        160        170        180 
ADPEVLKRPE YFGKFGKIHK VVINNSTSYA GSQGPSASAY VTYIRSEDAL RAIQCVNNVV 
       190        200        210        220        230        240 
VDGRTLKASL GTTKYCSYFL KNMQCPKPDC MYLHELGDEA ASFTKEEMQA GKHQEYEQKL 
       250        260        270        280        290        300 
LQELYKLNPN FLQLSTGSVD KNKNKVTPLQ RYDTPIDKPS DSLSIGNGDN SQQISNSDTP 
       310        320        330        340        350        360 
SPPPGLSKSN PVIPISSSNH SARSPFEGAV TESQSLFSDN FRHPNPIPSG LPPFPSSPQT 
       370        380        390        400        410        420 
PSDWPTAPEP QSLFTSETIP VSSSTDWQAA FGFGSSKQPE DDLGFDPFDV TRKALADLIE 
       430        440        450        460        470        480 
KELSVQDQPS LSPTSLQNAS SHTTTAKGPG SGFLHSAAPT NANSLNSTFS VLPQRFPQFQ 
       490        500        510        520        530        540 
QHRAVYNSFG FPGQAARYPW MAFPRNSIMH LNHTANPTSN SNFLDLNLPP QHNTGLGGIP 
       550        560        570    
IAGEEEVKVS TMPLSASSHS LQQGQQPTSL HTTVA



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8BT14-1-unknown MSRSPD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8BT14-1-unknown MSRSPD... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71188
    Q8BT14-1-unknown MSRSPD... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71189

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HTTVA 575 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...HTTVA 575 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt66806

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)