TopFIND 4.0

Q8C042: Enolase 4 {ECO:0000303|PubMed:23446454}

General Information

Protein names
- Enolase 4 {ECO:0000303|PubMed:23446454}
- 4.2.1.11
- 2-phospho-D-glycerate hydro-lyase
Gene names Eno4
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8C042

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGDEDGGRRG GITRDLQKLK QQAMAYYQEN DVPRKLEDLL NSTFYLQPAD VYGHLKANYF 
        70         80         90        100        110        120 
SKLAKPPSIC KIVGKTILDG LGLPTLQVEI SCTIQNFPKY ICAVAIPTHF EVVENALPEA 
       130        140        150        160        170        180 
LDAEDSERAQ AVNTAVQWIN QSITEELWGL VPSNQAEVDH RLRTFFEHKV QEDKERKELE 
       190        200        210        220        230        240 
KSQEELVPAP PPVTLPPPPP PPPPPPSKKK GQKAGRRDTL LEKPVSPPEP PEPVLHGSMA 
       250        260        270        280        290        300 
IGAVSLAVAK ASATLASDPL YLTLASLKHD QEQPSTFSMP LLMGSVLSCG KSSPGKLHLM 
       310        320        330        340        350        360 
KEVICIPSPG LTAKQSVELL LEIQKQVNRA METLPPPKQE TKKGHNGSKR AQPPITGKVS 
       370        380        390        400        410        420 
HLGCLTINYD AIEQPLLLLQ GICSNLGLEL GVNFHLAINC AGHELMDYSK GKYEVMVGTH 
       430        440        450        460        470        480 
KSAAEMVELY VDLINKYPSI IALIDPFRKE DAEQWDSLYA ALASRCYLIA GAASGSVSKL 
       490        500        510        520        530        540 
LECRNISTLK SHGLIIKHTN QTTMSDLVEI THLINGKKLL AVFGSTDSES SDDSLVDLAV 
       550        560        570        580        590        600 
GFGARFIKLG GLSRGERMTK YNRLLAIEEE LIQRGVWGFS EEHNFSFFQE DATATMAEET 
       610    
LGLLDSIFPT EVIEESAKT

Isoforms

- Isoform 2 of Enolase-like protein ENO4 - Isoform 3 of Enolase-like protein ENO4 - Isoform 2 of Enolase 4 - Isoform 3 of Enolase 4 - Isoform 4 of Enolase 4 - Isoform 5 of Enolase 4

Sequence View

        10         20         30         40         50         60 
MGDEDGGRRG GITRDLQKLK QQAMAYYQEN DVPRKLEDLL NSTFYLQPAD VYGHLKANYF 
        70         80         90        100        110        120 
SKLAKPPSIC KIVGKTILDG LGLPTLQVEI SCTIQNFPKY ICAVAIPTHF EVVENALPEA 
       130        140        150        160        170        180 
LDAEDSERAQ AVNTAVQWIN QSITEELWGL VPSNQAEVDH RLRTFFEHKV QEDKERKELE 
       190        200        210        220        230        240 
KSQEELVPAP PPVTLPPPPP PPPPPPSKKK GQKAGRRDTL LEKPVSPPEP PEPVLHGSMA 
       250        260        270        280        290        300 
IGAVSLAVAK ASATLASDPL YLTLASLKHD QEQPSTFSMP LLMGSVLSCG KSSPGKLHLM 
       310        320        330        340        350        360 
KEVICIPSPG LTAKQSVELL LEIQKQVNRA METLPPPKQE TKKGHNGSKR AQPPITGKVS 
       370        380        390        400        410        420 
HLGCLTINYD AIEQPLLLLQ GICSNLGLEL GVNFHLAINC AGHELMDYSK GKYEVMVGTH 
       430        440        450        460        470        480 
KSAAEMVELY VDLINKYPSI IALIDPFRKE DAEQWDSLYA ALASRCYLIA GAASGSVSKL 
       490        500        510        520        530        540 
LECRNISTLK SHGLIIKHTN QTTMSDLVEI THLINGKKLL AVFGSTDSES SDDSLVDLAV 
       550        560        570        580        590        600 
GFGARFIKLG GLSRGERMTK YNRLLAIEEE LIQRGVWGFS EEHNFSFFQE DATATMAEET 
       610    
LGLLDSIFPT EVIEESAKT         10         20         30         40         50         60 
MGDEDGGRRG GITRDLQKLK QQAMAYYQEN DVPRKLEDLL NSTFYLQPAD VYGHLKANYF 
        70         80         90        100        110        120 
SKLAKPPSIC KIVGKTILDG LGLPTLQVEI SCTIQNFPKY ICAVAIPTHF EVVENALPEA 
       130        140        150        160        170        180 
LDAEDSERAQ AVNTAVQWIN QSITEELWGL VPSNQAEVDH RLRTFFEHKV QEDKERKELE 
       190        200        210        220        230        240 
KSQEELVPAP PPVTLPPPPP PPPPPPSKKK GQKAGRRDTL LEKPVSPPEP PEPVLHGSMA 
       250        260        270        280        290        300 
IGAVSLAVAK ASATLASDPL YLTLASLKHD QEQPSTFSMP LLMGSVLSCG KSSPGKLHLM 
       310        320        330        340        350        360 
KEVICIPSPG LTAKQSVELL LEIQKQVNRA METLPPPKQE TKKGHNGSKR AQPPITGKVS 
       370        380        390        400        410        420 
HLGCLTINYD AIEQPLLLLQ GICSNLGLEL GVNFHLAINC AGHELMDYSK GKYEVMVGTH 
       430        440        450        460        470        480 
KSAAEMVELY VDLINKYPSI IALIDPFRKE DAEQWDSLYA ALASRCYLIA GAASGSVSKL 
       490        500        510        520        530        540 
LECRNISTLK SHGLIIKHTN QTTMSDLVEI THLINGKKLL AVFGSTDSES SDDSLVDLAV 
       550        560        570        580        590        600 
GFGARFIKLG GLSRGERMTK YNRLLAIEEE LIQRGVWGFS EEHNFSFFQE DATATMAEET 
       610    
LGLLDSIFPT EVIEESAKT         10         20         30         40         50         60 
MGDEDGGRRG GITRDLQKLK QQAMAYYQEN DVPRKLEDLL NSTFYLQPAD VYGHLKANYF 
        70         80         90        100        110        120 
SKLAKPPSIC KIVGKTILDG LGLPTLQVEI SCTIQNFPKY ICAVAIPTHF EVVENALPEA 
       130        140        150        160        170        180 
LDAEDSERAQ AVNTAVQWIN QSITEELWGL VPSNQAEVDH RLRTFFEHKV QEDKERKELE 
       190        200        210        220        230        240 
KSQEELVPAP PPVTLPPPPP PPPPPPSKKK GQKAGRRDTL LEKPVSPPEP PEPVLHGSMA 
       250        260        270        280        290        300 
IGAVSLAVAK ASATLASDPL YLTLASLKHD QEQPSTFSMP LLMGSVLSCG KSSPGKLHLM 
       310        320        330        340        350        360 
KEVICIPSPG LTAKQSVELL LEIQKQVNRA METLPPPKQE TKKGHNGSKR AQPPITGKVS 
       370        380        390        400        410        420 
HLGCLTINYD AIEQPLLLLQ GICSNLGLEL GVNFHLAINC AGHELMDYSK GKYEVMVGTH 
       430        440        450        460        470        480 
KSAAEMVELY VDLINKYPSI IALIDPFRKE DAEQWDSLYA ALASRCYLIA GAASGSVSKL 
       490        500        510        520        530        540 
LECRNISTLK SHGLIIKHTN QTTMSDLVEI THLINGKKLL AVFGSTDSES SDDSLVDLAV 
       550        560        570        580        590        600 
GFGARFIKLG GLSRGERMTK YNRLLAIEEE LIQRGVWGFS EEHNFSFFQE DATATMAEET 
       610    
LGLLDSIFPT EVIEESAKT         10         20         30         40         50         60 
MGDEDGGRRG GITRDLQKLK QQAMAYYQEN DVPRKLEDLL NSTFYLQPAD VYGHLKANYF 
        70         80         90        100        110        120 
SKLAKPPSIC KIVGKTILDG LGLPTLQVEI SCTIQNFPKY ICAVAIPTHF EVVENALPEA 
       130        140        150        160        170        180 
LDAEDSERAQ AVNTAVQWIN QSITEELWGL VPSNQAEVDH RLRTFFEHKV QEDKERKELE 
       190        200        210        220        230        240 
KSQEELVPAP PPVTLPPPPP PPPPPPSKKK GQKAGRRDTL LEKPVSPPEP PEPVLHGSMA 
       250        260        270        280        290        300 
IGAVSLAVAK ASATLASDPL YLTLASLKHD QEQPSTFSMP LLMGSVLSCG KSSPGKLHLM 
       310        320        330        340        350        360 
KEVICIPSPG LTAKQSVELL LEIQKQVNRA METLPPPKQE TKKGHNGSKR AQPPITGKVS 
       370        380        390        400        410        420 
HLGCLTINYD AIEQPLLLLQ GICSNLGLEL GVNFHLAINC AGHELMDYSK GKYEVMVGTH 
       430        440        450        460        470        480 
KSAAEMVELY VDLINKYPSI IALIDPFRKE DAEQWDSLYA ALASRCYLIA GAASGSVSKL 
       490        500        510        520        530        540 
LECRNISTLK SHGLIIKHTN QTTMSDLVEI THLINGKKLL AVFGSTDSES SDDSLVDLAV 
       550        560        570        580        590        600 
GFGARFIKLG GLSRGERMTK YNRLLAIEEE LIQRGVWGFS EEHNFSFFQE DATATMAEET 
       610    
LGLLDSIFPT EVIEESAKT         10         20         30         40         50         60 
MGDEDGGRRG GITRDLQKLK QQAMAYYQEN DVPRKLEDLL NSTFYLQPAD VYGHLKANYF 
        70         80         90        100        110        120 
SKLAKPPSIC KIVGKTILDG LGLPTLQVEI SCTIQNFPKY ICAVAIPTHF EVVENALPEA 
       130        140        150        160        170        180 
LDAEDSERAQ AVNTAVQWIN QSITEELWGL VPSNQAEVDH RLRTFFEHKV QEDKERKELE 
       190        200        210        220        230        240 
KSQEELVPAP PPVTLPPPPP PPPPPPSKKK GQKAGRRDTL LEKPVSPPEP PEPVLHGSMA 
       250        260        270        280        290        300 
IGAVSLAVAK ASATLASDPL YLTLASLKHD QEQPSTFSMP LLMGSVLSCG KSSPGKLHLM 
       310        320        330        340        350        360 
KEVICIPSPG LTAKQSVELL LEIQKQVNRA METLPPPKQE TKKGHNGSKR AQPPITGKVS 
       370        380        390        400        410        420 
HLGCLTINYD AIEQPLLLLQ GICSNLGLEL GVNFHLAINC AGHELMDYSK GKYEVMVGTH 
       430        440        450        460        470        480 
KSAAEMVELY VDLINKYPSI IALIDPFRKE DAEQWDSLYA ALASRCYLIA GAASGSVSKL 
       490        500        510        520        530        540 
LECRNISTLK SHGLIIKHTN QTTMSDLVEI THLINGKKLL AVFGSTDSES SDDSLVDLAV 
       550        560        570        580        590        600 
GFGARFIKLG GLSRGERMTK YNRLLAIEEE LIQRGVWGFS EEHNFSFFQE DATATMAEET 
       610    
LGLLDSIFPT EVIEESAKT         10         20         30         40         50         60 
MGDEDGGRRG GITRDLQKLK QQAMAYYQEN DVPRKLEDLL NSTFYLQPAD VYGHLKANYF 
        70         80         90        100        110        120 
SKLAKPPSIC KIVGKTILDG LGLPTLQVEI SCTIQNFPKY ICAVAIPTHF EVVENALPEA 
       130        140        150        160        170        180 
LDAEDSERAQ AVNTAVQWIN QSITEELWGL VPSNQAEVDH RLRTFFEHKV QEDKERKELE 
       190        200        210        220        230        240 
KSQEELVPAP PPVTLPPPPP PPPPPPSKKK GQKAGRRDTL LEKPVSPPEP PEPVLHGSMA 
       250        260        270        280        290        300 
IGAVSLAVAK ASATLASDPL YLTLASLKHD QEQPSTFSMP LLMGSVLSCG KSSPGKLHLM 
       310        320        330        340        350        360 
KEVICIPSPG LTAKQSVELL LEIQKQVNRA METLPPPKQE TKKGHNGSKR AQPPITGKVS 
       370        380        390        400        410        420 
HLGCLTINYD AIEQPLLLLQ GICSNLGLEL GVNFHLAINC AGHELMDYSK GKYEVMVGTH 
       430        440        450        460        470        480 
KSAAEMVELY VDLINKYPSI IALIDPFRKE DAEQWDSLYA ALASRCYLIA GAASGSVSKL 
       490        500        510        520        530        540 
LECRNISTLK SHGLIIKHTN QTTMSDLVEI THLINGKKLL AVFGSTDSES SDDSLVDLAV 
       550        560        570        580        590        600 
GFGARFIKLG GLSRGERMTK YNRLLAIEEE LIQRGVWGFS EEHNFSFFQE DATATMAEET 
       610    
LGLLDSIFPT EVIEESAKT



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8C042-1-unknown MGDEDG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8C042-1-unknown MGDEDG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73938
    Q8C042-1-unknown MGDEDG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73939

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ESAKT 619 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ESAKT 619 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt69556

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)