Q8C1B7: Septin-11

General Information

Protein names	- Septin-11
Gene names	Sept11
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8C1B7

5 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Septin-11 - Isoform 3 of Septin-11

Sequence View

        10         20         30         40         50         60
MAVAVGRPSN EELRNLSLSG HVGFDSLPDQ LVNKSTSQGF CFNILCVGET GIGKSTLMDT
        70         80         90        100        110        120
LFNTKFESDP ATHNEPGVRL KARSYELQES NVRLKLTIVD TVGFGDQINK DDSYKPIVEY
       130        140        150        160        170        180
IDAQFEAYLQ EELKIKRSLF NYHDTRIHAC LYFIAPTGHS LKSLDLVTMK KLDSKVNIIP
       190        200        210        220        230        240
IIAKADTIAK NELHKFKSKI MSELVSNGVQ IYQFPTDEET VAEINATMSV HLPFAVVGST
       250        260        270        280        290        300
EEVKIGNKMA KARQYPWGVV QVENENHCDF VKLREMLIRV NMEDLREQTH TRHYELYRRC
       310        320        330        340        350        360
KLEEMGFKDT DPDSKPFSLQ ETYEAKRNEF LGELQKKEEE MRQMFVMRVK EKEAELKEAE
       370        380        390        400        410        420
KELHEKFDLL KRTHQEEKKK VEDKKKELEE EVSNFQKKKA AAQLLQSQAQ QSGAQQTKKD
       430
KDKKNPWLCT E         10         20         30         40         50         60
MAVAVGRPSN EELRNLSLSG HVGFDSLPDQ LVNKSTSQGF CFNILCVGET GIGKSTLMDT
        70         80         90        100        110        120
LFNTKFESDP ATHNEPGVRL KARSYELQES NVRLKLTIVD TVGFGDQINK DDSYKPIVEY
       130        140        150        160        170        180
IDAQFEAYLQ EELKIKRSLF NYHDTRIHAC LYFIAPTGHS LKSLDLVTMK KLDSKVNIIP
       190        200        210        220        230        240
IIAKADTIAK NELHKFKSKI MSELVSNGVQ IYQFPTDEET VAEINATMSV HLPFAVVGST
       250        260        270        280        290        300
EEVKIGNKMA KARQYPWGVV QVENENHCDF VKLREMLIRV NMEDLREQTH TRHYELYRRC
       310        320        330        340        350        360
KLEEMGFKDT DPDSKPFSLQ ETYEAKRNEF LGELQKKEEE MRQMFVMRVK EKEAELKEAE
       370        380        390        400        410        420
KELHEKFDLL KRTHQEEKKK VEDKKKELEE EVSNFQKKKA AAQLLQSQAQ QSGAQQTKKD
       430
KDKKNPWLCT E

Filter Information:

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q8C1B7-1-unknown	MAVAVG...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89268
Q8C1B7-1-unknown	MAVAVG...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89269
Q8C1B7-2-unknown	MAVAVG...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q8C1B7-2-unknown	MAVAVG...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8C1B7-2-Acetylation	AVAVGR...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8C1B7-2-Acetylation	AVAVGR...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110385
Q8C1B7-2-Acetylation	AVAVGR...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110386
Q8C1B7-2-Acetylation	AVAVGR...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q8C1B7-243-unknown	VKIGNK...	243		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30763
Q8C1B7-243-unknown	VKIGNK...	243		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt148195
Q8C1B7-243-unknown	VKIGNK...	243		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt148196
Q8C1B7-320-unknown	QETYEA...	320		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30766
Q8C1B7-320-unknown	QETYEA...	320		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150330
Q8C1B7-320-unknown	QETYEA...	320		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150331

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GSTEEV	242	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30763
...GSTEEV	242	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131562
...GSTEEV	242	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131563
...KPFSLQ	319	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30766
...KPFSLQ	319	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133725
...KPFSLQ	319	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133726
...KDKKNP	425	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84887
...KDKKNP	425	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92729
...WLCTE	431	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	242	TEEV.\|.VKIG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> SEP11_MOUSE @242
CATE_MOUSE	319	FSLQ.\|.QETY	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> SEP11_MOUSE @319

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)