TopFIND 4.0

Q8C2A2: tRNA-splicing endonuclease subunit Sen54

General Information

Protein names
- tRNA-splicing endonuclease subunit Sen54
- tRNA-intron endonuclease Sen54
Gene names Tsen54
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8C2A2

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEPEPEPGSV EVPAGRVLSA SELRAARSRS QKLPQRSHGP KDFLPDGSEA QAERLRLCRQ 
        70         80         90        100        110        120 
ELWQLLAEER VERLGSLVAA EWKPEEGFVE LTSPAGKFWQ TMGYSEEGRQ RLHPEEALYL 
       130        140        150        160        170        180 
LECGSIQLFY QDLPLSIQEA YQLLLTEDTL SFLQYQVFSH LKRLGYVVRR FQLSSVVSPY 
       190        200        210        220        230        240 
ERQLNLDGYA QCLEDGSGKR KRSSSCRSVN KKPKVLQNSL PPVSLAASSS PACDQSSQYP 
       250        260        270        280        290        300 
EEKSQDSSPR QGSELPLQFL GSSEPCSDLA REDVGCDRES HKIENGAKGT PKLRWNFEQI 
       310        320        330        340        350        360 
SFPNMASDSR HTFLPAPAPE LLPANVIGRG TDAESWCQKL NQRREKLSRR DREQQAVVQQ 
       370        380        390        400        410        420 
FREDVNADPE VRGCSSWQEY KELLQRRQTQ KSQPRPPHLW GQSVTPLLDP DKADCPAAVL 
       430        440        450        460        470        480 
QHISVLQTTH LADGGYRLLE KSGGLQISFD VYQADAVATF RKNSPGKPYV RMCISGFDDP 
       490        500        510        520    
VPDLCSLKCL TYQSGDVPLI FALVDHGDIS FYSFRDFTLP RDLGH

Isoforms

- Isoform 2 of tRNA-splicing endonuclease subunit Sen54

Sequence View

        10         20         30         40         50         60 
MEPEPEPGSV EVPAGRVLSA SELRAARSRS QKLPQRSHGP KDFLPDGSEA QAERLRLCRQ 
        70         80         90        100        110        120 
ELWQLLAEER VERLGSLVAA EWKPEEGFVE LTSPAGKFWQ TMGYSEEGRQ RLHPEEALYL 
       130        140        150        160        170        180 
LECGSIQLFY QDLPLSIQEA YQLLLTEDTL SFLQYQVFSH LKRLGYVVRR FQLSSVVSPY 
       190        200        210        220        230        240 
ERQLNLDGYA QCLEDGSGKR KRSSSCRSVN KKPKVLQNSL PPVSLAASSS PACDQSSQYP 
       250        260        270        280        290        300 
EEKSQDSSPR QGSELPLQFL GSSEPCSDLA REDVGCDRES HKIENGAKGT PKLRWNFEQI 
       310        320        330        340        350        360 
SFPNMASDSR HTFLPAPAPE LLPANVIGRG TDAESWCQKL NQRREKLSRR DREQQAVVQQ 
       370        380        390        400        410        420 
FREDVNADPE VRGCSSWQEY KELLQRRQTQ KSQPRPPHLW GQSVTPLLDP DKADCPAAVL 
       430        440        450        460        470        480 
QHISVLQTTH LADGGYRLLE KSGGLQISFD VYQADAVATF RKNSPGKPYV RMCISGFDDP 
       490        500        510        520    
VPDLCSLKCL TYQSGDVPLI FALVDHGDIS FYSFRDFTLP RDLGH



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8C2A2-1-Acetylation MEPEPE... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8C2A2-1-Acetylation MEPEPE... 1 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt98044
    Q8C2A2-1-unknown MEPEPE... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt89254

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RDLGH 525 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RDLGH 525 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt84872

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)