TopFIND 4.0

Q8C3J5: Dedicator of cytokinesis protein 2

General Information

Protein names
- Dedicator of cytokinesis protein 2
- Protein Hch
Gene names Dock2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8C3J5

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAPWRKTDKE RHGVAIYNFQ GSEAQHLTLQ IGDVVRIQET CGDWYRGYLI KHKLSQGIFP 
        70         80         90        100        110        120 
TSFIHLKEVT VEKRRNIENI IPAEIPLAQE VTTTLWEWGS IWKQLYVASK KERFLQVQSM 
       130        140        150        160        170        180 
MYDLMEWRSQ LLSGTLPKDE LKELKQKVTS KIDYGNKILE LDLIVRDEDG NILDPDKTSV 
       190        200        210        220        230        240 
ISLFHAHEEA TYKITERIKE EMSKDQPDYG VYSRISSSPT HSLYVFVRNF VCRIGEDAEL 
       250        260        270        280        290        300 
FMSLYDPHKQ TVISENYLVR WGSKGFPKEI EMLNNLKVVF TDLGNKDLNR DKIFLICQIV 
       310        320        330        340        350        360 
RIGKMDLKDI NAKKCTQGLR RPFGVAVMDI TDIIKGKAES DEEKQHFIPF HPVSAENDFL 
       370        380        390        400        410        420 
HSLLGKVIAS KGDSGGQGLW VTMKMLVGDI IQIRKDYPHL VDRTTVVARK LGFPEIIMPG 
       430        440        450        460        470        480 
DVRNDIYITL LQGDFDKYTK TTQRNVEVIM CVCTEDGKVL PNAICVGAGD KAMNEYHSVV 
       490        500        510        520        530        540 
YYQVKQPRWM ETVKVAVPIE DMQRIHLRFM FRHRSSLESK DKGEKNFAMS YVKLMKEDGT 
       550        560        570        580        590        600 
TLHDGYHELV VLKGDSKKME DASAYLTLPS YRHPVENKGA TLSRSSSSVG GLSVSSRDVF 
       610        620        630        640        650        660 
SISTLVCSTK LTQNVGLLGL LKWRMKPQLL QENLEKLKIV DGEEVVKFLQ DTLDALFNIM 
       670        680        690        700        710        720 
MEHSQSNEYD ILVFDALIYI IGLIADRKFQ HFNTVLEAYI QQHFSATLAY KKLMTVLKTY 
       730        740        750        760        770        780 
LDTSSRGEQC EPILRTLKAL EYVFKFIVRS RTLFSQLYEG KEQMEFEESM RRLFESINNL 
       790        800        810        820        830        840 
MKSQYKTTIL LQVAALKYIP SVLHDVETVF DAKLLSQLLY EFYTCIPPVK LQKQKVQSMN 
       850        860        870        880        890        900 
EIVQSNLFKK QECRDILLPV ITKELKELLE QRDDGQHQAE KKHCVELLNS ILEVLSCQDA 
       910        920        930        940        950        960 
AFTYDHIQEI MVQLLRTVNR TVITMGRDHA LISHFVACMT AILDQMGDQH YSFYIETFQT 
       970        980        990       1000       1010       1020 
SSDLVDFLME TFIMFKDLIG KNVYPGDWMA MSMVQNRVFL RAINKFAETM NQKFLEHTSF 
      1030       1040       1050       1060       1070       1080 
EFQLWNNYFH LAVAFITQDS LQLEQFTHAK YNKILNKYGD MRRLIGFSIR DMWYKLGQNK 
      1090       1100       1110       1120       1130       1140 
ICFIPGMVGP ILEMTLIPEA ELRKATIPIF FDMMLCEYQR TGAFKKFENE IILKLDHEVE 
      1150       1160       1170       1180       1190       1200 
GGRGDEQYMQ LLESILMECT AEHPTIAKSV ENFVSLVKGL LEKLLDYRGV MTDESKDNRM 
      1210       1220       1230       1240       1250       1260 
SCTVNLLNFY KDNNREEMYI RYLYKLRDLH LDCENYTEAA YTLLLHTWLL KWSDEQCASQ 
      1270       1280       1290       1300       1310       1320 
VMQTGQQHPQ THRQLKETLY ETIIGYFDKG KMWEEAISLC KELAEQYEME IFDYELLSQN 
      1330       1340       1350       1360       1370       1380 
LTQQAKFYEN IMKILRTKPD YFAVGYYGQG FPSFLRNKVF IYRGKEYERR EDFQMQLLSQ 
      1390       1400       1410       1420       1430       1440 
FPNAEKMNTT SAPGDDVRNA PGQYIQCFTV QPVLDEHPRF KNKPVPDQII NFYKSNYVQK 
      1450       1460       1470       1480       1490       1500 
FHYSRPVRRG KVDPENEFAS MWIERTSFLT AYKLPGILRW FEVVHMSQTT ISPLENAIET 
      1510       1520       1530       1540       1550       1560 
MSTVNEKILM MINQYQSDES LPINPLSMLL NGIVDPAVMG GFAKYEKAFF TEEYSREHPE 
      1570       1580       1590       1600       1610       1620 
DQDKLSHLKD LIAWQIPFLG AGIKIHEKRV SDNLRPFHDR MEECFKNLKM KVEKEYGVRE 
      1630       1640       1650       1660       1670       1680 
MPDFEDRRVG RPRSMLRSYR QMSVISLASM HSDCSTPSKV PAESFDLESA PPKTPKVEEE 
      1690       1700       1710       1720       1730       1740 
PISPGSTLPE VKLRRSKKRT KRSSVVFADE KAATESDLKR LSRKQEFMSD TNLSEHAAIP 
      1750       1760       1770       1780       1790       1800 
ARVSILSQMS FASQSMPTIP ALTLSVAGVP GLDEANTSPR LSQTFFQVSD GDKKTLKKKK 
      1810       1820    
VNQFFKTMLA SKSSEESKQI PDFLSTNM

Isoforms



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LSTNM 1828 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)