TopFIND 4.0

Q8C436: Protein-lysine methyltransferase METTL21D

General Information

Protein names
- Protein-lysine methyltransferase METTL21D
- 2.1.1.-
- Methyltransferase-like protein 21D
- VCP lysine methyltransferase
- VCP-KMT
- Valosin-containing protein lysine methyltransferase
Gene names Vcpkmt
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8C436

3

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAAVEPEVE DPLWSFVRVL EKRDGTVLRL QQYGSGGVGC VVWDAAIVLS KYLETPGFSG 
        70         80         90        100        110        120 
DGAHALSRRS VLELGSGTGA VGLMAATLGA DVIVTDLEEL QDLLKMNIDM NKHLVTGSVQ 
       130        140        150        160        170        180 
AKVLKWGEDI EDLMSPDYIL MADCIYYEES LEPLLKTLKD LSGSETCIIC CYEQRTMGKN 
       190        200        210        220    
PEIEKKYFEL LQLDFDFEEI PLDKHDEEYR SEDIHIVYIR KKKPKPPS

Isoforms

- Isoform 2 of Protein-lysine methyltransferase METTL21D

Sequence View

        10         20         30         40         50         60 
MAAAVEPEVE DPLWSFVRVL EKRDGTVLRL QQYGSGGVGC VVWDAAIVLS KYLETPGFSG 
        70         80         90        100        110        120 
DGAHALSRRS VLELGSGTGA VGLMAATLGA DVIVTDLEEL QDLLKMNIDM NKHLVTGSVQ 
       130        140        150        160        170        180 
AKVLKWGEDI EDLMSPDYIL MADCIYYEES LEPLLKTLKD LSGSETCIIC CYEQRTMGKN 
       190        200        210        220    
PEIEKKYFEL LQLDFDFEEI PLDKHDEEYR SEDIHIVYIR KKKPKPPS



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...AATLGA 89 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt77300
    ...PKPPS 228 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)