Q8C5L3: CCR4-NOT transcription complex subunit 2

General Information

Protein names	- CCR4-NOT transcription complex subunit 2 - CCR4-associated factor 2
Gene names	Cnot2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8C5L3

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of CCR4-NOT transcription complex subunit 2 - Isoform 3 of CCR4-NOT transcription complex subunit 2

Sequence View

        10         20         30         40         50         60
MVRTDGHTLS EKRNYQVTNS MFGASRKKFV EGVDSDYHDE NMYYSQSSMF PHRSEKDMLA
        70         80         90        100        110        120
SPSTSGQLSQ FGASLYGQQS ALGLPMRGMS NNTPQLNRSL SQGTQLPSHV TPTTGVPTMS
       130        140        150        160        170        180
LHTPPSPSRG ILPMNPRNMM NHSQVGQGIG IPSRTNSMSS SGLGSPNRSS PSIICMPKQQ
       190        200        210        220        230        240
PSRQPFTVNS MSGFGMNRNQ AFGMNNSLSS NIFNGTDGSE NVTGLDLSDF PALADRNRRE
       250        260        270        280        290        300
GSGNPTPLIN PLAGRAPYVG MVTKPANEQS QDFSIHNEDF PALPGSSYKD PTSSNDDSKS
       310        320        330        340        350        360
NLSTSGKTTS STDGPKFPGD KSSTTQNNNQ QKKGIQVLPD GRVTNIPQGM VTDQFGMIGL
       370        380        390        400        410        420
LTFIRAAETD PGMVHLALGS DLTTLGLNLN SPENLYPKFA SPWASSPCRP QDIDFHVPSE
       430        440        450        460        470        480
YLTNIHIRDK LAAIKLGRYG EDLLFYLYYM NGGDVLQLLA AVELFNRDWR YHKEERVWIT
       490        500        510        520        530        540
RAPGMEPTMK TNTYERGTYY FFDCLNWRKV AKEFHLEYDK LEERPHLPST FNYNPAQQAF

        10         20         30         40         50         60
MVRTDGHTLS EKRNYQVTNS MFGASRKKFV EGVDSDYHDE NMYYSQSSMF PHRSEKDMLA
        70         80         90        100        110        120
SPSTSGQLSQ FGASLYGQQS ALGLPMRGMS NNTPQLNRSL SQGTQLPSHV TPTTGVPTMS
       130        140        150        160        170        180
LHTPPSPSRG ILPMNPRNMM NHSQVGQGIG IPSRTNSMSS SGLGSPNRSS PSIICMPKQQ
       190        200        210        220        230        240
PSRQPFTVNS MSGFGMNRNQ AFGMNNSLSS NIFNGTDGSE NVTGLDLSDF PALADRNRRE
       250        260        270        280        290        300
GSGNPTPLIN PLAGRAPYVG MVTKPANEQS QDFSIHNEDF PALPGSSYKD PTSSNDDSKS
       310        320        330        340        350        360
NLSTSGKTTS STDGPKFPGD KSSTTQNNNQ QKKGIQVLPD GRVTNIPQGM VTDQFGMIGL
       370        380        390        400        410        420
LTFIRAAETD PGMVHLALGS DLTTLGLNLN SPENLYPKFA SPWASSPCRP QDIDFHVPSE
       430        440        450        460        470        480
YLTNIHIRDK LAAIKLGRYG EDLLFYLYYM NGGDVLQLLA AVELFNRDWR YHKEERVWIT
       490        500        510        520        530        540
RAPGMEPTMK TNTYERGTYY FFDCLNWRKV AKEFHLEYDK LEERPHLPST FNYNPAQQAF

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8C5L3-1-unknown	MVRTDG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8C5L3-86-unknown	MRGMSN...	86	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71176
Q8C5L3-86-unknown	MRGMSN...	86	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96230
Q8C5L3-228-unknown	SDFPAL...	228	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30769
Q8C5L3-228-unknown	SDFPAL...	228	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt144441
Q8C5L3-228-unknown	SDFPAL...	228	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt147305

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TGLDLS	227	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30769
...TGLDLS	227	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127705
...TGLDLS	227	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130648
...AQQAF	540	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...AQQAF	540	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt66794
...AQQAF	540	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt66793

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	227	LDLS.\|.SDFP	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> CNOT2_MOUSE @227

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)