TopFIND 4.0

Q8C6L5: Cyclic GMP-AMP synthase {ECO:0000303|PubMed:23258413}

General Information

Protein names
- Cyclic GMP-AMP synthase {ECO:0000303|PubMed:23258413}
- cGAMP synthase {ECO:0000303|PubMed:23258413}
- cGAS {ECO:0000303|PubMed:23258413}
- m-cGAS {ECO:0000303|PubMed:23258413}
- 2.7.7.86 {ECO:0000269|PubMed:23647843, ECO:0000269|PubMed:28963528, ECO:0000269|PubMed:29976794, ECO:0000269|PubMed:30007416}
- 2'3'-cGAMP synthase {ECO:0000303|PubMed:23258413}
- Mab-21 domain-containing protein 1
Gene names Mb21d1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8C6L5

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEDPRRRTTA PRAKKPSAKR APTQPSRTRA HAESCGPQRG ARSRRAERDG DTTEKPRAPG 
        70         80         90        100        110        120 
PRVHPARATE LTKDAQPSAM DAAGATARPA VRVPQQQAIL DPELPAVREP QPPADPEARK 
       130        140        150        160        170        180 
VVRGPSHRRG ARSTGQPRAP RGSRKEPDKL KKVLDKLRLK RKDISEAAET VNKVVERLLR 
       190        200        210        220        230        240 
RMQKRESEFK GVEQLNTGSY YEHVKISAPN EFDVMFKLEV PRIELQEYYE TGAFYLVKFK 
       250        260        270        280        290        300 
RIPRGNPLSH FLEGEVLSAT KMLSKFRKII KEEVKEIKDI DVSVEKEKPG SPAVTLLIRN 
       310        320        330        340        350        360 
PEEISVDIIL ALESKGSWPI STKEGLPIQG WLGTKVRTNL RREPFYLVPK NAKDGNSFQG 
       370        380        390        400        410        420 
ETWRLSFSHT EKYILNNHGI EKTCCESSGA KCCRKECLKL MKYLLEQLKK EFQELDAFCS 
       430        440        450        460        470        480 
YHVKTAIFHM WTQDPQDSQW DPRNLSSCFD KLLAFFLECL RTEKLDHYFI PKFNLFSQEL 
       490        500    
IDRKSKEFLS KKIEYERNNG FPIFDKL

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8C6L5-1-Acetylation MEDPRR... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...IFDKL 507 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)