TopFIND 4.0

Q8C7D2: Protein cereblon

General Information

Protein names
- Protein cereblon
- Protein PiL
Gene names Crbn
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8C7D2

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAGEGDQQDA AHNMGNHLPL LPADSEDEDD EIEMEVEDQD SKEARKPNII NFDTSLPTSH 
        70         80         90        100        110        120 
TYLGADMEEF HGRTLHDDDS CQVIPVLPEV LMILIPGQTL PLQLSHPQEV SMVRNLIQKD 
       130        140        150        160        170        180 
RTFAVLAYSN VQEREAQFGT TAEIYAYREE QEFGIEVVKV KAIGRQRFKV LELRTQSDGI 
       190        200        210        220        230        240 
QQAKVQILPE CVLPSTMSAV QLESLNKCQV FPSKPISWED QYSCKWWQKY QKRKFHCANL 
       250        260        270        280        290        300 
TSWPRWLYSL YDAETLMDRI KKQLREWDEN LKDDSLPENP IDFSYRVAAC LPIDDVLRIQ 
       310        320        330        340        350        360 
LLKIGSAIQR LRCELDIMNK CTSLCCKQCQ ETEITTKNEI FSLSLCGPMA AYVNPHGYVH 
       370        380        390        400        410        420 
ETLTVYKASN LNLIGRPSTV HSWFPGYAWT IAQCKICASH IGWKFTATKK DMSPQKFWGL 
       430        440    
TRSALLPTIP ETEDEISPDK VILCL

Isoforms

- Isoform 2 of Protein cereblon - Isoform 3 of Protein cereblon

Sequence View

        10         20         30         40         50         60 
MAGEGDQQDA AHNMGNHLPL LPADSEDEDD EIEMEVEDQD SKEARKPNII NFDTSLPTSH 
        70         80         90        100        110        120 
TYLGADMEEF HGRTLHDDDS CQVIPVLPEV LMILIPGQTL PLQLSHPQEV SMVRNLIQKD 
       130        140        150        160        170        180 
RTFAVLAYSN VQEREAQFGT TAEIYAYREE QEFGIEVVKV KAIGRQRFKV LELRTQSDGI 
       190        200        210        220        230        240 
QQAKVQILPE CVLPSTMSAV QLESLNKCQV FPSKPISWED QYSCKWWQKY QKRKFHCANL 
       250        260        270        280        290        300 
TSWPRWLYSL YDAETLMDRI KKQLREWDEN LKDDSLPENP IDFSYRVAAC LPIDDVLRIQ 
       310        320        330        340        350        360 
LLKIGSAIQR LRCELDIMNK CTSLCCKQCQ ETEITTKNEI FSLSLCGPMA AYVNPHGYVH 
       370        380        390        400        410        420 
ETLTVYKASN LNLIGRPSTV HSWFPGYAWT IAQCKICASH IGWKFTATKK DMSPQKFWGL 
       430        440    
TRSALLPTIP ETEDEISPDK VILCL         10         20         30         40         50         60 
MAGEGDQQDA AHNMGNHLPL LPADSEDEDD EIEMEVEDQD SKEARKPNII NFDTSLPTSH 
        70         80         90        100        110        120 
TYLGADMEEF HGRTLHDDDS CQVIPVLPEV LMILIPGQTL PLQLSHPQEV SMVRNLIQKD 
       130        140        150        160        170        180 
RTFAVLAYSN VQEREAQFGT TAEIYAYREE QEFGIEVVKV KAIGRQRFKV LELRTQSDGI 
       190        200        210        220        230        240 
QQAKVQILPE CVLPSTMSAV QLESLNKCQV FPSKPISWED QYSCKWWQKY QKRKFHCANL 
       250        260        270        280        290        300 
TSWPRWLYSL YDAETLMDRI KKQLREWDEN LKDDSLPENP IDFSYRVAAC LPIDDVLRIQ 
       310        320        330        340        350        360 
LLKIGSAIQR LRCELDIMNK CTSLCCKQCQ ETEITTKNEI FSLSLCGPMA AYVNPHGYVH 
       370        380        390        400        410        420 
ETLTVYKASN LNLIGRPSTV HSWFPGYAWT IAQCKICASH IGWKFTATKK DMSPQKFWGL 
       430        440    
TRSALLPTIP ETEDEISPDK VILCL



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8C7D2-1-unknown MAGEGD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8C7D2-1-unknown MAGEGD... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71649

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)