TopFIND 4.0

Q8C7W7: 5' exonuclease Apollo

General Information

Protein names
- 5' exonuclease Apollo
- 3.1.-.-
- DNA cross-link repair 1B protein
- SNM1 homolog B
Gene names Dclre1b
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8C7W7

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MNGVVIPQTP IAVDFWSLRR AGSARLFFLT HMHCDHTVGL SSTWARPLYC SPITACLLHR 
        70         80         90        100        110        120 
RLQVSKHWIR ALEVGESHVL PLDEIGQETM TVTLIDANHC PGSVMFLFEG YFGTILYTGD 
       130        140        150        160        170        180 
FRYTPSMLKE PALILGKQIH TLYLDNTNCN PALVLPSRQE ATQQIVQLIR QFPQHNIKIG 
       190        200        210        220        230        240 
LYSLGKESLL EQLALEFRTW VVLSPQRLEL VQLLGLADVF TVEEEAGRIH AVDHTEICHS 
       250        260        270        280        290        300 
AMLQWNQSHP TIAIFPTSRK VRSPHPSIYT VPYSDHSSYS ELRAFVAALR PCQVVPIVHQ 
       310        320        330        340        350        360 
KPCGEFFQDS LSPRLAMPLI PHSVQQYMSS SSRKTNVLWQ LERRLKRPRT QGVVFESPEE 
       370        380        390        400        410        420 
KANQVKVDRD SKKHKKENLS PWAGHLERLC PHPLQARKQL FPDFCRKERD EPVLFCDSNK 
       430        440        450        460        470        480 
MATVLTAPLE FSVQLQPIDE FLFPETREKI GLESPLLSRG DSGSPARGNQ SDCVGCGSPP 
       490        500        510        520        530        540 
AHISRAVPLT PESRGLALKY LLTPVHFLQA GFSSRNFDKQ VEKHQRVQRS SPAVLSPVDV 
   
G

Isoforms

- Isoform 2 of 5' exonuclease Apollo - Isoform 3 of 5' exonuclease Apollo

Sequence View

        10         20         30         40         50         60 
MNGVVIPQTP IAVDFWSLRR AGSARLFFLT HMHCDHTVGL SSTWARPLYC SPITACLLHR 
        70         80         90        100        110        120 
RLQVSKHWIR ALEVGESHVL PLDEIGQETM TVTLIDANHC PGSVMFLFEG YFGTILYTGD 
       130        140        150        160        170        180 
FRYTPSMLKE PALILGKQIH TLYLDNTNCN PALVLPSRQE ATQQIVQLIR QFPQHNIKIG 
       190        200        210        220        230        240 
LYSLGKESLL EQLALEFRTW VVLSPQRLEL VQLLGLADVF TVEEEAGRIH AVDHTEICHS 
       250        260        270        280        290        300 
AMLQWNQSHP TIAIFPTSRK VRSPHPSIYT VPYSDHSSYS ELRAFVAALR PCQVVPIVHQ 
       310        320        330        340        350        360 
KPCGEFFQDS LSPRLAMPLI PHSVQQYMSS SSRKTNVLWQ LERRLKRPRT QGVVFESPEE 
       370        380        390        400        410        420 
KANQVKVDRD SKKHKKENLS PWAGHLERLC PHPLQARKQL FPDFCRKERD EPVLFCDSNK 
       430        440        450        460        470        480 
MATVLTAPLE FSVQLQPIDE FLFPETREKI GLESPLLSRG DSGSPARGNQ SDCVGCGSPP 
       490        500        510        520        530        540 
AHISRAVPLT PESRGLALKY LLTPVHFLQA GFSSRNFDKQ VEKHQRVQRS SPAVLSPVDV 
   
G         10         20         30         40         50         60 
MNGVVIPQTP IAVDFWSLRR AGSARLFFLT HMHCDHTVGL SSTWARPLYC SPITACLLHR 
        70         80         90        100        110        120 
RLQVSKHWIR ALEVGESHVL PLDEIGQETM TVTLIDANHC PGSVMFLFEG YFGTILYTGD 
       130        140        150        160        170        180 
FRYTPSMLKE PALILGKQIH TLYLDNTNCN PALVLPSRQE ATQQIVQLIR QFPQHNIKIG 
       190        200        210        220        230        240 
LYSLGKESLL EQLALEFRTW VVLSPQRLEL VQLLGLADVF TVEEEAGRIH AVDHTEICHS 
       250        260        270        280        290        300 
AMLQWNQSHP TIAIFPTSRK VRSPHPSIYT VPYSDHSSYS ELRAFVAALR PCQVVPIVHQ 
       310        320        330        340        350        360 
KPCGEFFQDS LSPRLAMPLI PHSVQQYMSS SSRKTNVLWQ LERRLKRPRT QGVVFESPEE 
       370        380        390        400        410        420 
KANQVKVDRD SKKHKKENLS PWAGHLERLC PHPLQARKQL FPDFCRKERD EPVLFCDSNK 
       430        440        450        460        470        480 
MATVLTAPLE FSVQLQPIDE FLFPETREKI GLESPLLSRG DSGSPARGNQ SDCVGCGSPP 
       490        500        510        520        530        540 
AHISRAVPLT PESRGLALKY LLTPVHFLQA GFSSRNFDKQ VEKHQRVQRS SPAVLSPVDV 
   
G



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(REFRESH)

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Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8C7W7-1-unknown MNGVVI... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8C7W7-1-unknown MNGVVI... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt72467
    Q8C7W7-127-unknown MLKEPA... 127 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt72466
    Q8C7W7-127-unknown MLKEPA... 127 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt96898

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PVDVG 541 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...PVDVG 541 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt68084

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)