Q8CBY8: Dynactin subunit 4

General Information

Protein names	- Dynactin subunit 4 - Dynactin subunit p62
Gene names	Dctn4
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8CBY8

5 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MASLLQSERV LYLVQGEKKV RAPLSQLYFC RYCSELRSLE CVSHEVDSHY CPSCLENMPS
        70         80         90        100        110        120
AEAKLKKNRC ANCFDCPGCM HTLSTRATSI STQLPDDPAK TTMKKAYYLA CGFCRWTSRD
       130        140        150        160        170        180
VGMADKSVAS GGWQEPENPH TQRMNKLIEY YQQLAQKEKV ERDRKKLARR RNYMPLAFSQ
       190        200        210        220        230        240
HTIHVVDKYS LGTRLQRPRA GASISTLAGL SLREGEDQKE VKIEPAQAVA EVEPLPEDYY
       250        260        270        280        290        300
TRPVNLTEVT TLQQRLLQPD LQPVSASQLY PRHKHLLIKR SLRCRKCEHN LSKPEFNPTS
       310        320        330        340        350        360
IKFKIQLVAV NYIPEVRIMS IPNLRYMKES QVLLTLTNPV ENLTHVTLLE CDEGDPDNIN
       370        380        390        400        410        420
STAKVVVPPK ELILAGKDAA AEYDELAEPQ DFQDDPDIVA FRKANKVGIF IKVTPQREEG
       430        440        450        460
EVTVCFKMKH DFKNLAAPIR PVEEGDQGTE VIWLTQHVEL SFGPLLP

Isoforms

- Isoform 2 of Dynactin subunit 4

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q8CBY8-2-unknown	MASLLQ...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q8CBY8-2-unknown	MASLLQ...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8CBY8-1-unknown	MASLLQ...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72493
Q8CBY8-2-Acetylation	ASLLQS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8CBY8-2-Acetylation	ASLLQS...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110342
Q8CBY8-2-Acetylation	ASLLQS...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q8CBY8-12-unknown	YLVQGE...	12		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30779
Q8CBY8-12-unknown	YLVQGE...	12		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt136357
Q8CBY8-247-unknown	TEVTTL...	247		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30781
Q8CBY8-247-unknown	TEVTTL...	247		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt148076

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SERVLY	11	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30779
...RPVNLT	246	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30781
...RPVNLT	246	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131440
...GPLLP	467	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GPLLP	467	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68111

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	11	RVLY.\|.YLVQ	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> DCTN4_MOUSE @11
CATE_MOUSE	246	VNLT.\|.TEVT	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> DCTN4_MOUSE @246

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)