TopFIND 4.0

Q8CDB0: MAP kinase-interacting serine/threonine-protein kinase 2

General Information

Protein names
- MAP kinase-interacting serine/threonine-protein kinase 2
- 2.7.11.1
- MAP kinase signal-integrating kinase 2
- MAPK signal-integrating kinase 2
- Mnk2
Gene names Mknk2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8CDB0

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVQKRTAELQ GFHRSFKGQN PFELAFSLDL AQHRDSDFSP QCEARPDMPS SQPIDIPDAK 
        70         80         90        100        110        120 
KRGRKKKRCR ATDSFSGRFE DVYQLQEDVL GEGAHARVQT CVNLITNQEY AVKIIEKQLG 
       130        140        150        160        170        180 
HIRSRVFREV EMLYQCQGHR NVLELIEFFE EEDRFYLVFE KMRGGSILSH IHRRRHFNEL 
       190        200        210        220        230        240 
EASVVVQDVA SALDFLHNKG IAHRDLKPEN ILCEHPNQVS PVKICDFDLG SGIKLNGDCS 
       250        260        270        280        290        300 
PISTPELLTP CGSAEYMAPE VVEAFSEEAS IYDKRCDLWS LGVILYILLS GYPPFVGHCG 
       310        320        330        340        350        360 
SDCGWDRGEA CPACQNMLFE SIQEGKYEFP DKDWSHISFA AKDLISKLLV RDAKQRLSAA 
       370        380        390        400        410        420 
QVLQHPWVQG CAPENTLPTP LVLQRNSCAK DLTSFAAEAI AMNRQLAQCE EDAGQDQPVV 
       430        440        450    
IRATSRCLQL SPPSQSKLAQ RRQRASLSAT PVVLVGDRA

Isoforms

- Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 2

Sequence View

        10         20         30         40         50         60 
MVQKRTAELQ GFHRSFKGQN PFELAFSLDL AQHRDSDFSP QCEARPDMPS SQPIDIPDAK 
        70         80         90        100        110        120 
KRGRKKKRCR ATDSFSGRFE DVYQLQEDVL GEGAHARVQT CVNLITNQEY AVKIIEKQLG 
       130        140        150        160        170        180 
HIRSRVFREV EMLYQCQGHR NVLELIEFFE EEDRFYLVFE KMRGGSILSH IHRRRHFNEL 
       190        200        210        220        230        240 
EASVVVQDVA SALDFLHNKG IAHRDLKPEN ILCEHPNQVS PVKICDFDLG SGIKLNGDCS 
       250        260        270        280        290        300 
PISTPELLTP CGSAEYMAPE VVEAFSEEAS IYDKRCDLWS LGVILYILLS GYPPFVGHCG 
       310        320        330        340        350        360 
SDCGWDRGEA CPACQNMLFE SIQEGKYEFP DKDWSHISFA AKDLISKLLV RDAKQRLSAA 
       370        380        390        400        410        420 
QVLQHPWVQG CAPENTLPTP LVLQRNSCAK DLTSFAAEAI AMNRQLAQCE EDAGQDQPVV 
       430        440        450    
IRATSRCLQL SPPSQSKLAQ RRQRASLSAT PVVLVGDRA



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VGDRA 459 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...VGDRA 459 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt76851

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)