Q8CFA1: Interleukin-1 receptor-associated kinase-like 2

General Information

Protein names	- Interleukin-1 receptor-associated kinase-like 2 - IRAK-2 - mu-IRAK-2
Gene names	Irak2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8CFA1

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MACYIYQLPS WVLDDLCRNI DTLSEWDWMQ FASYVITDLT QLRKIKSMER VQGVSITREL
        70         80         90        100        110        120
LWWWSMRQAT VQQLVDLLCH LELYRAAQIV LSWKPVPEST SPLPAFPEAV KPGAVATSRR
       130        140        150        160        170        180
NLKDEQEKVR PVKPRSLLDT GPIMAGAQRQ RPCEMDAPCS LKTDAPDSPQ SKYCSTSTSA
       190        200        210        220        230        240
PKQERLLGLP GDRLFWSEAD VVQATEDFDQ SHRISEGTFA DIYQGQRNGV AFAFKKLREV
       250        260        270        280        290        300
AGSSPGSMDR FLQAEMQLCL RCCHANVLPL LGFCTGRQFH SLIYPYMANG SLHDRLWAQG
       310        320        330        340        350        360
NSDMLPWPQR ASICSGLLLA VEHLHSLDII HSNVKSANVL LDQHLNPKLA HPVAHPHPDN
       370        380        390        400        410        420
KKTKYTVMRT HLFQASAAYL PEHFIRVGQL TKQVDIFSCG IVLAEVLTGI PAMDKDRSPV
       430        440        450        460        470        480
YLKDLLLSEI PNSTSSVCSR KTSMGKAVVK EICQRHVEKR AGLLPEACEE AWATAVSVCL
       490        500        510        520        530        540
RRRNASVEEA RVSLAGVEEQ LRGQLSLPWS RVSEATGSSS NTPEETDDVD NSSLSVPSLV
       550        560        570        580        590        600
MMASCPGAAS SPLFTGHGAA QPSTSGRQEA DSSSEACTGP QTPQNATETS WKIEINEAKR
       610        620
RLMENIVLYK EERLDSSELF GP

Isoforms

- Isoform 2 of Interleukin-1 receptor-associated kinase-like 2 - Isoform 3 of Interleukin-1 receptor-associated kinase-like 2 - Isoform 4 of Interleukin-1 receptor-associated kinase-like 2

Sequence View

        10         20         30         40         50         60
MACYIYQLPS WVLDDLCRNI DTLSEWDWMQ FASYVITDLT QLRKIKSMER VQGVSITREL
        70         80         90        100        110        120
LWWWSMRQAT VQQLVDLLCH LELYRAAQIV LSWKPVPEST SPLPAFPEAV KPGAVATSRR
       130        140        150        160        170        180
NLKDEQEKVR PVKPRSLLDT GPIMAGAQRQ RPCEMDAPCS LKTDAPDSPQ SKYCSTSTSA
       190        200        210        220        230        240
PKQERLLGLP GDRLFWSEAD VVQATEDFDQ SHRISEGTFA DIYQGQRNGV AFAFKKLREV
       250        260        270        280        290        300
AGSSPGSMDR FLQAEMQLCL RCCHANVLPL LGFCTGRQFH SLIYPYMANG SLHDRLWAQG
       310        320        330        340        350        360
NSDMLPWPQR ASICSGLLLA VEHLHSLDII HSNVKSANVL LDQHLNPKLA HPVAHPHPDN
       370        380        390        400        410        420
KKTKYTVMRT HLFQASAAYL PEHFIRVGQL TKQVDIFSCG IVLAEVLTGI PAMDKDRSPV
       430        440        450        460        470        480
YLKDLLLSEI PNSTSSVCSR KTSMGKAVVK EICQRHVEKR AGLLPEACEE AWATAVSVCL
       490        500        510        520        530        540
RRRNASVEEA RVSLAGVEEQ LRGQLSLPWS RVSEATGSSS NTPEETDDVD NSSLSVPSLV
       550        560        570        580        590        600
MMASCPGAAS SPLFTGHGAA QPSTSGRQEA DSSSEACTGP QTPQNATETS WKIEINEAKR
       610        620
RLMENIVLYK EERLDSSELF GP         10         20         30         40         50         60
MACYIYQLPS WVLDDLCRNI DTLSEWDWMQ FASYVITDLT QLRKIKSMER VQGVSITREL
        70         80         90        100        110        120
LWWWSMRQAT VQQLVDLLCH LELYRAAQIV LSWKPVPEST SPLPAFPEAV KPGAVATSRR
       130        140        150        160        170        180
NLKDEQEKVR PVKPRSLLDT GPIMAGAQRQ RPCEMDAPCS LKTDAPDSPQ SKYCSTSTSA
       190        200        210        220        230        240
PKQERLLGLP GDRLFWSEAD VVQATEDFDQ SHRISEGTFA DIYQGQRNGV AFAFKKLREV
       250        260        270        280        290        300
AGSSPGSMDR FLQAEMQLCL RCCHANVLPL LGFCTGRQFH SLIYPYMANG SLHDRLWAQG
       310        320        330        340        350        360
NSDMLPWPQR ASICSGLLLA VEHLHSLDII HSNVKSANVL LDQHLNPKLA HPVAHPHPDN
       370        380        390        400        410        420
KKTKYTVMRT HLFQASAAYL PEHFIRVGQL TKQVDIFSCG IVLAEVLTGI PAMDKDRSPV
       430        440        450        460        470        480
YLKDLLLSEI PNSTSSVCSR KTSMGKAVVK EICQRHVEKR AGLLPEACEE AWATAVSVCL
       490        500        510        520        530        540
RRRNASVEEA RVSLAGVEEQ LRGQLSLPWS RVSEATGSSS NTPEETDDVD NSSLSVPSLV
       550        560        570        580        590        600
MMASCPGAAS SPLFTGHGAA QPSTSGRQEA DSSSEACTGP QTPQNATETS WKIEINEAKR
       610        620
RLMENIVLYK EERLDSSELF GP         10         20         30         40         50         60
MACYIYQLPS WVLDDLCRNI DTLSEWDWMQ FASYVITDLT QLRKIKSMER VQGVSITREL
        70         80         90        100        110        120
LWWWSMRQAT VQQLVDLLCH LELYRAAQIV LSWKPVPEST SPLPAFPEAV KPGAVATSRR
       130        140        150        160        170        180
NLKDEQEKVR PVKPRSLLDT GPIMAGAQRQ RPCEMDAPCS LKTDAPDSPQ SKYCSTSTSA
       190        200        210        220        230        240
PKQERLLGLP GDRLFWSEAD VVQATEDFDQ SHRISEGTFA DIYQGQRNGV AFAFKKLREV
       250        260        270        280        290        300
AGSSPGSMDR FLQAEMQLCL RCCHANVLPL LGFCTGRQFH SLIYPYMANG SLHDRLWAQG
       310        320        330        340        350        360
NSDMLPWPQR ASICSGLLLA VEHLHSLDII HSNVKSANVL LDQHLNPKLA HPVAHPHPDN
       370        380        390        400        410        420
KKTKYTVMRT HLFQASAAYL PEHFIRVGQL TKQVDIFSCG IVLAEVLTGI PAMDKDRSPV
       430        440        450        460        470        480
YLKDLLLSEI PNSTSSVCSR KTSMGKAVVK EICQRHVEKR AGLLPEACEE AWATAVSVCL
       490        500        510        520        530        540
RRRNASVEEA RVSLAGVEEQ LRGQLSLPWS RVSEATGSSS NTPEETDDVD NSSLSVPSLV
       550        560        570        580        590        600
MMASCPGAAS SPLFTGHGAA QPSTSGRQEA DSSSEACTGP QTPQNATETS WKIEINEAKR
       610        620
RLMENIVLYK EERLDSSELF GP

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8CFA1-1-unknown	MACYIY...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8CFA1-1-unknown	MACYIY...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78065
Q8CFA1-1-unknown	MACYIY...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78066
Q8CFA1-144-unknown	MAGAQR...	144	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78067
Q8CFA1-144-unknown	MAGAQR...	144	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109383
Q8CFA1-144-unknown	MAGAQR...	144	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109384

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ELFGP	622	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ELFGP	622	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73685
...ELFGP	622	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73684
...ELFGP	622	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73683

TopFIND

Q8CFA1: Interleukin-1 receptor-associated kinase-like 2

General Information

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates