Q8CG19: Latent-transforming growth factor beta-binding protein 1 {ECO:0000303|PubMed:12711388, ECO:0000303|PubMed:12711389}
| Protein names | - Latent-transforming growth factor beta-binding protein 1 {ECO:0000303|PubMed:12711388, ECO:0000303|PubMed:12711389} - LTBP-1 {ECO:0000303|PubMed:12711388, ECO:0000303|PubMed:12711389} - Transforming growth factor beta-1-binding protein 1 {ECO:0000250|UniProtKB:Q14766} - TGF-beta1-BP-1 {ECO:0000250|UniProtKB:Q14766} |
|---|---|
| Gene names | Ltbp1 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q8CG19 |
1
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAGAWLRWGL LLWAGLLAWS AHGRVRRITY VVRPGPGLPA GALPLAGPPR TFNVALDARY
70 80 90 100 110 120
SRSSTAASSR ALAGPPAERT RRTSQPGGAA LPGLRSPLPP EPARPGGPSR QLHSKAGAQT
130 140 150 160 170 180
AVTRFAKHGR QVVRSQVQQD AQSAGGSRLQ VQQKQQLQGI NVCGGQCCHG WSKPPGSQRC
190 200 210 220 230 240
TKPSCVPPCQ NGGMCLRPQL CVCKPGSKGK ACEITAAQDT MPPAFGGQNP GSSWAPLEQA
250 260 270 280 290 300
AKHTSTKKAD TLPRVSPVAQ MTLTLKPKPS MGLSQQIHPQ VAPLSSQNVM IRHGQTQEYL
310 320 330 340 350 360
LKPKYFPAPK VVSAEQSTEG SFSLRYGQEQ GTAPFQVSNH TGRIKVVFTP SICKVTCTKG
370 380 390 400 410 420
NCQNSCQKGN TTTLISENGH AADTLTATNF RVVICHLPCM NGGQCSSRDK CQCPPNFTGK
430 440 450 460 470 480
LCQIPVLGAS MPKLYQHAQQ QGKALGSHVI HSTHTLPLTM TSQQGVKVKF PPNIVNIHVK
490 500 510 520 530 540
HPPEASVQIH QVSRIDSPGG QKVKEAQPGQ SQVSYQGLPV QKTQTVHSTY SHQQLIPHVY
550 560 570 580 590 600
PVAAKTQLGR CFQETIGSQC GKALPGLSKQ EDCCGTVGTS WGFNKCQKCP KKQSYHGYTQ
610 620 630 640 650 660
MMECLQGYKR VNNTFCQDIN ECQLQGVCPN GECLNTMGSY RCSCKMGFGP DPTFSSCVPD
670 680 690 700 710 720
PPVISEEKGP CYRLVSPGRH CMHPLSVHLT KQICCCSVGK AWGPHCEKCP LPGTAAFKEI
730 740 750 760 770 780
CPGGMGYTVS GVHRRRPIHQ HIGKEAVYVK PKNTQPVAKS THPPPLPAKE EPVEALTSSW
790 800 810 820 830 840
EHGPRGAEPE VVTAPPEKEI PSLDQEKTRL EPGQPQLSPG VSTIHLHPQF PVVVEKTSPP
850 860 870 880 890 900
VPVEVAPEAS TSSASQVIAP TQVTEINECT VNPDICGAGH CINLPVRYTC ICYEGYKFSE
910 920 930 940 950 960
QLRKCVDIDE CAQVRHLCSQ GRCENTEGSF LCVCPAGFMA SEEGTNCIDV DECLRPDMCR
970 980 990 1000 1010 1020
DGRCINTAGA FRCEYCDSGY RMSRRGYCED IDECLKPSTC PEEQCVNTPG SYQCVPCTEG
1030 1040 1050 1060 1070 1080
FRGWNGQCLD VDECLQPKVC TNGSCTNLEG SYMCSCHRGY SPTPDHRHCQ DIDECQQGNL
1090 1100 1110 1120 1130 1140
CMNGQCRNTD GSFRCTCGQG YQLSAAKDQC EDIDECEHHH LCSHGQCRNT EGSFQCVCNQ
1150 1160 1170 1180 1190 1200
GYRASVLGDH CEDINECLED SSVCQGGDCI NTAGSYDCTC PDGFQLNDNK GCQDINECAQ
1210 1220 1230 1240 1250 1260
PGLCGSHGEC LNTQGSFHCV CEQGFSISAD GRTCEDIDEC VNNTVCDSHG FCDNTAGSFR
1270 1280 1290 1300 1310 1320
CLCYQGFQAP QDGQGCVDVN ECELLSGVCG EAFCENVEGS FLCVCADENQ EYSPMTGQCR
1330 1340 1350 1360 1370 1380
SRVTEDSGVD RQPREEKKEC YYNLNDASLC DNVLAPNVTK QECCCTSGAG WGDNCEIFPC
1390 1400 1410 1420 1430 1440
PVQGTAEFTE MCPRGKGLVP AGESSYDTGG ENYKDADECL LFGEEICKNG YCLNTQPGYE
1450 1460 1470 1480 1490 1500
CYCKQGTYYD PVKLQCFDMD ECQDPNSCID GQCVNTEGSY NCFCTHPMVL DASEKRCVQP
1510 1520 1530 1540 1550 1560
TESNEQIEET DVYQDLCWEH LSEEYVCSRP LVGKQTTYTE CCCLYGEAWG MQCALCPMKD
1570 1580 1590 1600 1610 1620
SDDYAQLCNI PVTGRRRPYG RDALVDFSEQ YGPETDPYFI QDRFLNSFEE LQAEECGILN
1630 1640 1650 1660 1670 1680
GCENGRCVRV QEGYTCDCFD GYHLDMAKMT CVDVNECSEL NNRMSLCKNA KCINTEGSYK
1690 1700 1710
CLCLPGYIPS DKPNYCTPLN SALNLDKESD LE
Isoforms
- Isoform Short of Latent-transforming growth factor beta-binding protein 1 - Isoform 3 of Latent-transforming growth factor beta-binding protein 1Sequence View
10 20 30 40 50 60
MAGAWLRWGL LLWAGLLAWS AHGRVRRITY VVRPGPGLPA GALPLAGPPR TFNVALDARY
70 80 90 100 110 120
SRSSTAASSR ALAGPPAERT RRTSQPGGAA LPGLRSPLPP EPARPGGPSR QLHSKAGAQT
130 140 150 160 170 180
AVTRFAKHGR QVVRSQVQQD AQSAGGSRLQ VQQKQQLQGI NVCGGQCCHG WSKPPGSQRC
190 200 210 220 230 240
TKPSCVPPCQ NGGMCLRPQL CVCKPGSKGK ACEITAAQDT MPPAFGGQNP GSSWAPLEQA
250 260 270 280 290 300
AKHTSTKKAD TLPRVSPVAQ MTLTLKPKPS MGLSQQIHPQ VAPLSSQNVM IRHGQTQEYL
310 320 330 340 350 360
LKPKYFPAPK VVSAEQSTEG SFSLRYGQEQ GTAPFQVSNH TGRIKVVFTP SICKVTCTKG
370 380 390 400 410 420
NCQNSCQKGN TTTLISENGH AADTLTATNF RVVICHLPCM NGGQCSSRDK CQCPPNFTGK
430 440 450 460 470 480
LCQIPVLGAS MPKLYQHAQQ QGKALGSHVI HSTHTLPLTM TSQQGVKVKF PPNIVNIHVK
490 500 510 520 530 540
HPPEASVQIH QVSRIDSPGG QKVKEAQPGQ SQVSYQGLPV QKTQTVHSTY SHQQLIPHVY
550 560 570 580 590 600
PVAAKTQLGR CFQETIGSQC GKALPGLSKQ EDCCGTVGTS WGFNKCQKCP KKQSYHGYTQ
610 620 630 640 650 660
MMECLQGYKR VNNTFCQDIN ECQLQGVCPN GECLNTMGSY RCSCKMGFGP DPTFSSCVPD
670 680 690 700 710 720
PPVISEEKGP CYRLVSPGRH CMHPLSVHLT KQICCCSVGK AWGPHCEKCP LPGTAAFKEI
730 740 750 760 770 780
CPGGMGYTVS GVHRRRPIHQ HIGKEAVYVK PKNTQPVAKS THPPPLPAKE EPVEALTSSW
790 800 810 820 830 840
EHGPRGAEPE VVTAPPEKEI PSLDQEKTRL EPGQPQLSPG VSTIHLHPQF PVVVEKTSPP
850 860 870 880 890 900
VPVEVAPEAS TSSASQVIAP TQVTEINECT VNPDICGAGH CINLPVRYTC ICYEGYKFSE
910 920 930 940 950 960
QLRKCVDIDE CAQVRHLCSQ GRCENTEGSF LCVCPAGFMA SEEGTNCIDV DECLRPDMCR
970 980 990 1000 1010 1020
DGRCINTAGA FRCEYCDSGY RMSRRGYCED IDECLKPSTC PEEQCVNTPG SYQCVPCTEG
1030 1040 1050 1060 1070 1080
FRGWNGQCLD VDECLQPKVC TNGSCTNLEG SYMCSCHRGY SPTPDHRHCQ DIDECQQGNL
1090 1100 1110 1120 1130 1140
CMNGQCRNTD GSFRCTCGQG YQLSAAKDQC EDIDECEHHH LCSHGQCRNT EGSFQCVCNQ
1150 1160 1170 1180 1190 1200
GYRASVLGDH CEDINECLED SSVCQGGDCI NTAGSYDCTC PDGFQLNDNK GCQDINECAQ
1210 1220 1230 1240 1250 1260
PGLCGSHGEC LNTQGSFHCV CEQGFSISAD GRTCEDIDEC VNNTVCDSHG FCDNTAGSFR
1270 1280 1290 1300 1310 1320
CLCYQGFQAP QDGQGCVDVN ECELLSGVCG EAFCENVEGS FLCVCADENQ EYSPMTGQCR
1330 1340 1350 1360 1370 1380
SRVTEDSGVD RQPREEKKEC YYNLNDASLC DNVLAPNVTK QECCCTSGAG WGDNCEIFPC
1390 1400 1410 1420 1430 1440
PVQGTAEFTE MCPRGKGLVP AGESSYDTGG ENYKDADECL LFGEEICKNG YCLNTQPGYE
1450 1460 1470 1480 1490 1500
CYCKQGTYYD PVKLQCFDMD ECQDPNSCID GQCVNTEGSY NCFCTHPMVL DASEKRCVQP
1510 1520 1530 1540 1550 1560
TESNEQIEET DVYQDLCWEH LSEEYVCSRP LVGKQTTYTE CCCLYGEAWG MQCALCPMKD
1570 1580 1590 1600 1610 1620
SDDYAQLCNI PVTGRRRPYG RDALVDFSEQ YGPETDPYFI QDRFLNSFEE LQAEECGILN
1630 1640 1650 1660 1670 1680
GCENGRCVRV QEGYTCDCFD GYHLDMAKMT CVDVNECSEL NNRMSLCKNA KCINTEGSYK
1690 1700 1710
CLCLPGYIPS DKPNYCTPLN SALNLDKESD LE
10 20 30 40 50 60
MAGAWLRWGL LLWAGLLAWS AHGRVRRITY VVRPGPGLPA GALPLAGPPR TFNVALDARY
70 80 90 100 110 120
SRSSTAASSR ALAGPPAERT RRTSQPGGAA LPGLRSPLPP EPARPGGPSR QLHSKAGAQT
130 140 150 160 170 180
AVTRFAKHGR QVVRSQVQQD AQSAGGSRLQ VQQKQQLQGI NVCGGQCCHG WSKPPGSQRC
190 200 210 220 230 240
TKPSCVPPCQ NGGMCLRPQL CVCKPGSKGK ACEITAAQDT MPPAFGGQNP GSSWAPLEQA
250 260 270 280 290 300
AKHTSTKKAD TLPRVSPVAQ MTLTLKPKPS MGLSQQIHPQ VAPLSSQNVM IRHGQTQEYL
310 320 330 340 350 360
LKPKYFPAPK VVSAEQSTEG SFSLRYGQEQ GTAPFQVSNH TGRIKVVFTP SICKVTCTKG
370 380 390 400 410 420
NCQNSCQKGN TTTLISENGH AADTLTATNF RVVICHLPCM NGGQCSSRDK CQCPPNFTGK
430 440 450 460 470 480
LCQIPVLGAS MPKLYQHAQQ QGKALGSHVI HSTHTLPLTM TSQQGVKVKF PPNIVNIHVK
490 500 510 520 530 540
HPPEASVQIH QVSRIDSPGG QKVKEAQPGQ SQVSYQGLPV QKTQTVHSTY SHQQLIPHVY
550 560 570 580 590 600
PVAAKTQLGR CFQETIGSQC GKALPGLSKQ EDCCGTVGTS WGFNKCQKCP KKQSYHGYTQ
610 620 630 640 650 660
MMECLQGYKR VNNTFCQDIN ECQLQGVCPN GECLNTMGSY RCSCKMGFGP DPTFSSCVPD
670 680 690 700 710 720
PPVISEEKGP CYRLVSPGRH CMHPLSVHLT KQICCCSVGK AWGPHCEKCP LPGTAAFKEI
730 740 750 760 770 780
CPGGMGYTVS GVHRRRPIHQ HIGKEAVYVK PKNTQPVAKS THPPPLPAKE EPVEALTSSW
790 800 810 820 830 840
EHGPRGAEPE VVTAPPEKEI PSLDQEKTRL EPGQPQLSPG VSTIHLHPQF PVVVEKTSPP
850 860 870 880 890 900
VPVEVAPEAS TSSASQVIAP TQVTEINECT VNPDICGAGH CINLPVRYTC ICYEGYKFSE
910 920 930 940 950 960
QLRKCVDIDE CAQVRHLCSQ GRCENTEGSF LCVCPAGFMA SEEGTNCIDV DECLRPDMCR
970 980 990 1000 1010 1020
DGRCINTAGA FRCEYCDSGY RMSRRGYCED IDECLKPSTC PEEQCVNTPG SYQCVPCTEG
1030 1040 1050 1060 1070 1080
FRGWNGQCLD VDECLQPKVC TNGSCTNLEG SYMCSCHRGY SPTPDHRHCQ DIDECQQGNL
1090 1100 1110 1120 1130 1140
CMNGQCRNTD GSFRCTCGQG YQLSAAKDQC EDIDECEHHH LCSHGQCRNT EGSFQCVCNQ
1150 1160 1170 1180 1190 1200
GYRASVLGDH CEDINECLED SSVCQGGDCI NTAGSYDCTC PDGFQLNDNK GCQDINECAQ
1210 1220 1230 1240 1250 1260
PGLCGSHGEC LNTQGSFHCV CEQGFSISAD GRTCEDIDEC VNNTVCDSHG FCDNTAGSFR
1270 1280 1290 1300 1310 1320
CLCYQGFQAP QDGQGCVDVN ECELLSGVCG EAFCENVEGS FLCVCADENQ EYSPMTGQCR
1330 1340 1350 1360 1370 1380
SRVTEDSGVD RQPREEKKEC YYNLNDASLC DNVLAPNVTK QECCCTSGAG WGDNCEIFPC
1390 1400 1410 1420 1430 1440
PVQGTAEFTE MCPRGKGLVP AGESSYDTGG ENYKDADECL LFGEEICKNG YCLNTQPGYE
1450 1460 1470 1480 1490 1500
CYCKQGTYYD PVKLQCFDMD ECQDPNSCID GQCVNTEGSY NCFCTHPMVL DASEKRCVQP
1510 1520 1530 1540 1550 1560
TESNEQIEET DVYQDLCWEH LSEEYVCSRP LVGKQTTYTE CCCLYGEAWG MQCALCPMKD
1570 1580 1590 1600 1610 1620
SDDYAQLCNI PVTGRRRPYG RDALVDFSEQ YGPETDPYFI QDRFLNSFEE LQAEECGILN
1630 1640 1650 1660 1670 1680
GCENGRCVRV QEGYTCDCFD GYHLDMAKMT CVDVNECSEL NNRMSLCKNA KCINTEGSYK
1690 1700 1710
CLCLPGYIPS DKPNYCTPLN SALNLDKESD LE
Protein Neighborhood
Domains & Features
1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q8CG19-24-unknown | RVRRIT... | 24 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...ESDLE | 1712 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...ESDLE | 1712 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt75664 | |||
| ...ESDLE | 1712 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt75663 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|