TopFIND 4.0

Q8CHB8: Tubulin polyglutamylase TTLL5

General Information

Protein names
- Tubulin polyglutamylase TTLL5
- 6.-.-.-
- Tubulin--tyrosine ligase-like protein 5
Gene names Ttll5
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8CHB8

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPVVMARDLE ETASSSEDED LANQEDHPCI MWTGGCRRIP VLVFHAEAIL TKDNNIRVIG 
        70         80         90        100        110        120 
ERYHLSYKIV RTDSRLVRSI LTAHGFHEVH PSSTDYNLMW TGSHLKPFLL RTLSEAQKVN 
       130        140        150        160        170        180 
HFPRSYELTR KDRLYKNIIR MQHTHGFKAF HILPQTFLLP AEYAEFCNSY SKDRGPWIVK 
       190        200        210        220        230        240 
PVASSRGRGV YLINNPNQIS LEENILVSRY INNPLLIDDF KFDVRLYVLV TSYDPLVIYL 
       250        260        270        280        290        300 
YEEGLARFAT VRYDQGSKNI RNQFMHLTNY SVNKKSGDYV SCDDPEVEDY GNKWSMSAML 
       310        320        330        340        350        360 
RYLKQEGKDT TALMAHVEDL IIKTIISAEL AIATACKTFV PHRSSCFELY GFDVLIDNTL 
       370        380        390        400        410        420 
KPWLLEVNLS PSLACDAPLD LKIKASMISD MFTVVGFVCQ DPAQRTSNRS IYPSFESSRR 
       430        440        450        460        470        480 
NPFQKPQRTR PLSASDAEMK NLVASAREKV PGKLGGSVLG LSMEEIKVLR RVKEENDRRG 
       490        500        510        520        530        540 
GFIRIFPTSE TWEIYGSYLE HKTSMNYMLA TRLFQDRGNP RRSLLTGRAR VSTEGAPELK 
       550        560        570        580        590        600 
VESMNSKAKL HAALYERKLL SLEVRKRRRR SGRLRAMRPK YPVIAQPAEM NIKTETESEE 
       610        620        630        640        650        660 
EEEVGLDNDD EEQEASQEES AGSLGENQAK YTPSLTVIVE NSPRDNAMKV AEWTNKGEPC 
       670        680        690        700        710        720 
CKIEAQEPES KFNLMQILQD NGNLSKVQAR LAFSAYLQHV QIRLTKDSGG QTLSPSWAAK 
       730        740        750        760        770        780 
EDEQMELVVR FLKRASSNLQ HSLRMVLPSR RLALLERRRI LAHQLGDFIG VYNKETEQMA 
       790        800        810        820        830        840 
EKKSKKKLEE EEEDGVNAES FQEFIRQASE AELEEVLTFY TQKNKSASVF LGTHSKSSKN 
       850        860        870        880        890        900 
SSSYSDSGAK GDHPETIQEV KIKQPKQQQA TEIHADKLSR FTTSSGKEAK LVYTNCSSFC 
       910        920        930        940        950        960 
SPAAVLLQRL PSSHLSSVIT TSALSAGPGH HASLSQIPPA VPSLPHQPAL LLSPVPDNAP 
       970        980        990       1000       1010       1020 
PSIHSGTQNV SPAGLPRCRS GSYTIGPFSS FQSAAHIYSQ KLSRPSSAKA AGSCHPHKHH 
      1030       1040       1050       1060       1070       1080 
SGIAKTQKEG EDVSLNRRYN QSLVTAELQR LAEKQAARQY SPASHISLLT QQVTNLNLAS 
      1090       1100       1110       1120       1130       1140 
SVINRSSAST PPTLRPVISP SGPTWSIQPD LHASETHSSP PGSRSLQTGG FAWEGEVENN 
      1150       1160       1170       1180       1190       1200 
AYSKTTGVVP QHKYHPTAGS YQLHFALQQL EQQKLQSRQL LDQSRARHQA IFGSQTLPNS 
      1210       1220       1230       1240       1250       1260 
SLWTMNNGPG CRISSATTGG QKPNTLPQKV VAPPNSSTLV SKPASNHKQV LRKPASQRAS 
      1270       1280       1290       1300       1310       1320 
KGSSAEGQLN GLQSSLNPAA FMPITNSTGS LEAPQVIFAR SKPLPTQSGA LATVIGQRKS 
   
KSVKSGTI

Isoforms

- Isoform 2 of Tubulin polyglutamylase TTLL5

Sequence View

        10         20         30         40         50         60 
MPVVMARDLE ETASSSEDED LANQEDHPCI MWTGGCRRIP VLVFHAEAIL TKDNNIRVIG 
        70         80         90        100        110        120 
ERYHLSYKIV RTDSRLVRSI LTAHGFHEVH PSSTDYNLMW TGSHLKPFLL RTLSEAQKVN 
       130        140        150        160        170        180 
HFPRSYELTR KDRLYKNIIR MQHTHGFKAF HILPQTFLLP AEYAEFCNSY SKDRGPWIVK 
       190        200        210        220        230        240 
PVASSRGRGV YLINNPNQIS LEENILVSRY INNPLLIDDF KFDVRLYVLV TSYDPLVIYL 
       250        260        270        280        290        300 
YEEGLARFAT VRYDQGSKNI RNQFMHLTNY SVNKKSGDYV SCDDPEVEDY GNKWSMSAML 
       310        320        330        340        350        360 
RYLKQEGKDT TALMAHVEDL IIKTIISAEL AIATACKTFV PHRSSCFELY GFDVLIDNTL 
       370        380        390        400        410        420 
KPWLLEVNLS PSLACDAPLD LKIKASMISD MFTVVGFVCQ DPAQRTSNRS IYPSFESSRR 
       430        440        450        460        470        480 
NPFQKPQRTR PLSASDAEMK NLVASAREKV PGKLGGSVLG LSMEEIKVLR RVKEENDRRG 
       490        500        510        520        530        540 
GFIRIFPTSE TWEIYGSYLE HKTSMNYMLA TRLFQDRGNP RRSLLTGRAR VSTEGAPELK 
       550        560        570        580        590        600 
VESMNSKAKL HAALYERKLL SLEVRKRRRR SGRLRAMRPK YPVIAQPAEM NIKTETESEE 
       610        620        630        640        650        660 
EEEVGLDNDD EEQEASQEES AGSLGENQAK YTPSLTVIVE NSPRDNAMKV AEWTNKGEPC 
       670        680        690        700        710        720 
CKIEAQEPES KFNLMQILQD NGNLSKVQAR LAFSAYLQHV QIRLTKDSGG QTLSPSWAAK 
       730        740        750        760        770        780 
EDEQMELVVR FLKRASSNLQ HSLRMVLPSR RLALLERRRI LAHQLGDFIG VYNKETEQMA 
       790        800        810        820        830        840 
EKKSKKKLEE EEEDGVNAES FQEFIRQASE AELEEVLTFY TQKNKSASVF LGTHSKSSKN 
       850        860        870        880        890        900 
SSSYSDSGAK GDHPETIQEV KIKQPKQQQA TEIHADKLSR FTTSSGKEAK LVYTNCSSFC 
       910        920        930        940        950        960 
SPAAVLLQRL PSSHLSSVIT TSALSAGPGH HASLSQIPPA VPSLPHQPAL LLSPVPDNAP 
       970        980        990       1000       1010       1020 
PSIHSGTQNV SPAGLPRCRS GSYTIGPFSS FQSAAHIYSQ KLSRPSSAKA AGSCHPHKHH 
      1030       1040       1050       1060       1070       1080 
SGIAKTQKEG EDVSLNRRYN QSLVTAELQR LAEKQAARQY SPASHISLLT QQVTNLNLAS 
      1090       1100       1110       1120       1130       1140 
SVINRSSAST PPTLRPVISP SGPTWSIQPD LHASETHSSP PGSRSLQTGG FAWEGEVENN 
      1150       1160       1170       1180       1190       1200 
AYSKTTGVVP QHKYHPTAGS YQLHFALQQL EQQKLQSRQL LDQSRARHQA IFGSQTLPNS 
      1210       1220       1230       1240       1250       1260 
SLWTMNNGPG CRISSATTGG QKPNTLPQKV VAPPNSSTLV SKPASNHKQV LRKPASQRAS 
      1270       1280       1290       1300       1310       1320 
KGSSAEGQLN GLQSSLNPAA FMPITNSTGS LEAPQVIFAR SKPLPTQSGA LATVIGQRKS 
   
KSVKSGTI



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8CHB8-1-unknown MPVVMA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8CHB8-1-unknown MPVVMA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93402

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LLSLEV 563 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt89020
    ...KSGTI 1328 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)