TopFIND 4.0

Q8CIH5: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

General Information

Protein names
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
- 3.1.4.11
- Phosphoinositide phospholipase C-gamma-2
- Phospholipase C-gamma-2
- PLC-gamma-2
Gene names Plcg2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8CIH5

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTTMVNVDTL PEYEKSQIKR ALELGTVMTV FNARKSTPER RTVQMIMETR QVAWSKTADK 
        70         80         90        100        110        120 
IEGFLDIMEI KEIRPGKNSK DFERAKAVRH KAECCFTILY GTQFVLSTLS LATDSKEDAV 
       130        140        150        160        170        180 
KWLSGLKILH QEAMSASTPT MIESWLRKQI YSVDQTRRNS ISLRELKTIL PLVNFKVSGI 
       190        200        210        220        230        240 
KFLKDKLVEI GAQKDELSFE QFHLFYKKLM FDQQKSILDE FKKDSSVFIL GNTDRPDASA 
       250        260        270        280        290        300 
VYLQDFQRFL LHEQQELWAQ DLNKVRERMT KFIDDTMRET AEPFLFVDEF LTYLFSRENS 
       310        320        330        340        350        360 
IWDEKYDAVD MQDMNNPLSH YWISSSHNTY LTGDQLRSES STEAYIRCLR AGCRCIELDC 
       370        380        390        400        410        420 
WDGPDGKPII YHGWTRTTKI KFDDVVQAIR DHAFVTSSFP VILSIEEHCS VEQQRHMAKV 
       430        440        450        460        470        480 
FKEVLGDMLL TKPTEASADQ LPSPSQLREK IIIKHKKLGP KGDVDVNVED KKDEHKPQGE 
       490        500        510        520        530        540 
LYMWDSIDQK WTRHYCAIAD AKLSFGDDIE QAVEEEPVQD TPPTELHFGE KWFHKKVESR 
       550        560        570        580        590        600 
TSAEKLLQEY CAETGAKDGT FLVRESETFP NDYTLSFWRS GRVQHCRIRS TMENGVMKYY 
       610        620        630        640        650        660 
LTDNLTFNSI YALIQHYREA HLRCAEFELR LTDPVPNPNP HESKPWYYDS LSRGEAEDML 
       670        680        690        700        710        720 
MRIPRDGAFL IRKREGTNSY AITFRARGKV KHCRINRDGR HFVLGTSAYF ESLVELVSYY 
       730        740        750        760        770        780 
EKHALYRKMR LRYPVTPELL ERYNMERDIN SLYDVSRMYV DPSEINPSMP QRTVKALYDY 
       790        800        810        820        830        840 
KAKRSDELTF CRGALIHNVS KEPGGWWKGD YGTRIQQYFP SNYVEDISAG DAEEMEKQII 
       850        860        870        880        890        900 
EDNPLGSLCK GILDLNTYNV VKAPQGKNQK AFVFILEPKK QGDPPVEFAT DRVEELFEWF 
       910        920        930        940        950        960 
QSIREITWKM DTKENNMKYW ERNQSIAIEL SDLVVYCKPT SKTKDHLENP DFREIRSFVE 
       970        980        990       1000       1010       1020 
TKADSIVRQK PVDLLRYNQK GLTRVYPKGQ RVDSSNYDPF RLWLCGSQMV ALNFQTPDKY 
      1030       1040       1050       1060       1070       1080 
MQMNHALFSL NGRTGYVLQP ESMRSEKYDP MPLESQRKIL MTLTVKVLGA RHLPKLGRSI 
      1090       1100       1110       1120       1130       1140 
ACPFVEVEIC GAEYDSNKFK TTVVNDNGLS PVWAPTQEKV TFEIYDPNLA FLRFVVYEED 
      1150       1160       1170       1180       1190       1200 
MFSDPNFLAH ATYPIKGIKS GFRSVPLKNG YSEDIELASL LVFCEMRPVL ESEEELYSSC 
      1210       1220       1230       1240       1250       1260 
RQLRRRQEEL NNQLFLYDTH QNLRGANRDA LVKEFNVNEN QLQLYQEKCN RRLREKRVSN 
   
SRFYS

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8CIH5-1-unknown MTTMVN... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8CIH5-959-unknown VETKAD... 959 inferred from cleavage unknown TopFIND Inferred from cleavage TC30808

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)