TopFIND 4.0

Q8CIM8: Integrator complex subunit 4

General Information

Protein names
- Integrator complex subunit 4
- Int4
Gene names Ints4
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8CIM8

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAHLKKRVY EEFTKVVQQQ QEEIATKKLR LTKPSKSAAL HIDLCKATSP ADALQYLLQF 
        70         80         90        100        110        120 
ARKPVEAESV EGVVRILLEH YYKENDPSVR LKIASLLGLL SKTAGFSPDC IMDDAINILQ 
       130        140        150        160        170        180 
NEKSHQVLAQ LLDTLLAIGS KLPENQATQV RLVDVACKHL TDTSHGVRNK CLQLLGNLGS 
       190        200        210        220        230        240 
LEKSVTKDTE GSAARDVQKI IGDHFSDQDP RVRTAAIKAM LQLHERGLKL HQTIYNQACK 
       250        260        270        280        290        300 
LLSDDYEQVR SAAVQLIWVV SQLYPESIVP IPSSNEEIRL VDDAFGKICH MVSDGSWVVR 
       310        320        330        340        350        360 
VQAAKLLGSM EQVSSHFLEQ TLDKKLMSDL RRKRTAHERA KELYSSGEFS SGRKWGDDAP 
       370        380        390        400        410        420 
KEEIDTGAVN LIESGACGAF VHGLEDEMYE VRIAAVEALC MLAQSSPSFA EKCLDFLVDM 
       430        440        450        460        470        480 
FNDEIEEVRL QSIHTMRKIS NNITLREDQL DTVLAVLEDS SRDIREALHE LLCCTNVSTK 
       490        500        510        520        530        540 
EGIHLALVEL LKNLTKYPTD RDSIWKCLKF LGSRHPTLVL PLVPELLSTH PFFDTAEPDM 
       550        560        570        580        590        600 
DDPAYIAVLV LIFNAAKTCP TMPALFSDHT LRHYAYLRDS LSHLVPALRL PGRKLVSSTV 
       610        620        630        640        650        660 
PSNITPHEDP SQQFLQQSLE RVYSVQHLDP QGAQELLEFT IRDLQRLGEL QSELAGVADF 
       670        680        690        700        710        720 
SATYLQCQLL LIKALQEKLW NVAAPLYLKQ SDLASAAAKQ IMEETYKMEF MYSGVENKQV 
       730        740        750        760        770        780 
VIIQHMRLQA KALQLIVTAR TTRGVDPLFG MCEKFLQEVD FFQRCFIADL PHLQDSFVDK 
       790        800        810        820        830        840 
LLDLMPRLMA SKPVEVIKIL QTMLRQSTFL HLPLPEQIHK ASATIIEPAG ESDNPLRFTS 
       850        860        870        880        890        900 
GLVVALDVDA TLEHVQDPQN TVKVQVLYPD GQAQMIHPKP ADFRNPGPGR HRLLTQVYLS 
       910        920        930        940        950        960 
HTAWTEPCQV EVRLLLAYNS GARIPKSPWL EGSEMSPQVE TSIEGTIPFS KPVKVYIMPK 
   
PARR

Isoforms

- Isoform 2 of Integrator complex subunit 4 - Isoform 3 of Integrator complex subunit 4

Sequence View

        10         20         30         40         50         60 
MAAHLKKRVY EEFTKVVQQQ QEEIATKKLR LTKPSKSAAL HIDLCKATSP ADALQYLLQF 
        70         80         90        100        110        120 
ARKPVEAESV EGVVRILLEH YYKENDPSVR LKIASLLGLL SKTAGFSPDC IMDDAINILQ 
       130        140        150        160        170        180 
NEKSHQVLAQ LLDTLLAIGS KLPENQATQV RLVDVACKHL TDTSHGVRNK CLQLLGNLGS 
       190        200        210        220        230        240 
LEKSVTKDTE GSAARDVQKI IGDHFSDQDP RVRTAAIKAM LQLHERGLKL HQTIYNQACK 
       250        260        270        280        290        300 
LLSDDYEQVR SAAVQLIWVV SQLYPESIVP IPSSNEEIRL VDDAFGKICH MVSDGSWVVR 
       310        320        330        340        350        360 
VQAAKLLGSM EQVSSHFLEQ TLDKKLMSDL RRKRTAHERA KELYSSGEFS SGRKWGDDAP 
       370        380        390        400        410        420 
KEEIDTGAVN LIESGACGAF VHGLEDEMYE VRIAAVEALC MLAQSSPSFA EKCLDFLVDM 
       430        440        450        460        470        480 
FNDEIEEVRL QSIHTMRKIS NNITLREDQL DTVLAVLEDS SRDIREALHE LLCCTNVSTK 
       490        500        510        520        530        540 
EGIHLALVEL LKNLTKYPTD RDSIWKCLKF LGSRHPTLVL PLVPELLSTH PFFDTAEPDM 
       550        560        570        580        590        600 
DDPAYIAVLV LIFNAAKTCP TMPALFSDHT LRHYAYLRDS LSHLVPALRL PGRKLVSSTV 
       610        620        630        640        650        660 
PSNITPHEDP SQQFLQQSLE RVYSVQHLDP QGAQELLEFT IRDLQRLGEL QSELAGVADF 
       670        680        690        700        710        720 
SATYLQCQLL LIKALQEKLW NVAAPLYLKQ SDLASAAAKQ IMEETYKMEF MYSGVENKQV 
       730        740        750        760        770        780 
VIIQHMRLQA KALQLIVTAR TTRGVDPLFG MCEKFLQEVD FFQRCFIADL PHLQDSFVDK 
       790        800        810        820        830        840 
LLDLMPRLMA SKPVEVIKIL QTMLRQSTFL HLPLPEQIHK ASATIIEPAG ESDNPLRFTS 
       850        860        870        880        890        900 
GLVVALDVDA TLEHVQDPQN TVKVQVLYPD GQAQMIHPKP ADFRNPGPGR HRLLTQVYLS 
       910        920        930        940        950        960 
HTAWTEPCQV EVRLLLAYNS GARIPKSPWL EGSEMSPQVE TSIEGTIPFS KPVKVYIMPK 
   
PARR         10         20         30         40         50         60 
MAAHLKKRVY EEFTKVVQQQ QEEIATKKLR LTKPSKSAAL HIDLCKATSP ADALQYLLQF 
        70         80         90        100        110        120 
ARKPVEAESV EGVVRILLEH YYKENDPSVR LKIASLLGLL SKTAGFSPDC IMDDAINILQ 
       130        140        150        160        170        180 
NEKSHQVLAQ LLDTLLAIGS KLPENQATQV RLVDVACKHL TDTSHGVRNK CLQLLGNLGS 
       190        200        210        220        230        240 
LEKSVTKDTE GSAARDVQKI IGDHFSDQDP RVRTAAIKAM LQLHERGLKL HQTIYNQACK 
       250        260        270        280        290        300 
LLSDDYEQVR SAAVQLIWVV SQLYPESIVP IPSSNEEIRL VDDAFGKICH MVSDGSWVVR 
       310        320        330        340        350        360 
VQAAKLLGSM EQVSSHFLEQ TLDKKLMSDL RRKRTAHERA KELYSSGEFS SGRKWGDDAP 
       370        380        390        400        410        420 
KEEIDTGAVN LIESGACGAF VHGLEDEMYE VRIAAVEALC MLAQSSPSFA EKCLDFLVDM 
       430        440        450        460        470        480 
FNDEIEEVRL QSIHTMRKIS NNITLREDQL DTVLAVLEDS SRDIREALHE LLCCTNVSTK 
       490        500        510        520        530        540 
EGIHLALVEL LKNLTKYPTD RDSIWKCLKF LGSRHPTLVL PLVPELLSTH PFFDTAEPDM 
       550        560        570        580        590        600 
DDPAYIAVLV LIFNAAKTCP TMPALFSDHT LRHYAYLRDS LSHLVPALRL PGRKLVSSTV 
       610        620        630        640        650        660 
PSNITPHEDP SQQFLQQSLE RVYSVQHLDP QGAQELLEFT IRDLQRLGEL QSELAGVADF 
       670        680        690        700        710        720 
SATYLQCQLL LIKALQEKLW NVAAPLYLKQ SDLASAAAKQ IMEETYKMEF MYSGVENKQV 
       730        740        750        760        770        780 
VIIQHMRLQA KALQLIVTAR TTRGVDPLFG MCEKFLQEVD FFQRCFIADL PHLQDSFVDK 
       790        800        810        820        830        840 
LLDLMPRLMA SKPVEVIKIL QTMLRQSTFL HLPLPEQIHK ASATIIEPAG ESDNPLRFTS 
       850        860        870        880        890        900 
GLVVALDVDA TLEHVQDPQN TVKVQVLYPD GQAQMIHPKP ADFRNPGPGR HRLLTQVYLS 
       910        920        930        940        950        960 
HTAWTEPCQV EVRLLLAYNS GARIPKSPWL EGSEMSPQVE TSIEGTIPFS KPVKVYIMPK 
   
PARR



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8CIM8-1-unknown MAAHLK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8CIM8-1-unknown MAAHLK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt77950
    Q8CIM8-1-unknown MAAHLK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt77951

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...DSIWKC 506 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt73568
    ...KPARR 964 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)