TopFIND 4.0

Q8CIR4: Transient receptor potential cation channel subfamily M member 6

General Information

Protein names
- Transient receptor potential cation channel subfamily M member 6
- 2.7.11.1
- Channel kinase 2
- Melastatin-related TRP cation channel 6
Gene names Trpm6
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8CIR4

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MQVKKSWIEG VFYKRECNKF IPSSKDPHRC TPGCQICHNL VRCYCGRLIE EHHGLDRAWN 
        70         80         90        100        110        120 
LSVTEGHGDE QWSVEKHTVK SPTDTFGTIN FQDGEHIHHS KYIRTSWDTK SDHLLHLMLK 
       130        140        150        160        170        180 
EWNMELPKLV ISVHGGLQNF KISSKLKETF SQGLVKAAET TGAWIITEGI NSGVSKHVGD 
       190        200        210        220        230        240 
ALKAHSSKSL RKIWTVGIPP WGVIENQREL VGKDVVCMYQ TLGNPLSKLT TLNCMHSHFI 
       250        260        270        280        290        300 
LCDDGTVGMY GNEEKLRRNL EKHLSMQKIH TCSRQGVPVV GLVMEGGPNV ILWVWETVKN 
       310        320        330        340        350        360 
KEPVVVCEGT GRAADLLAFT YKHLEDGGIL RPQVKEELFC LIQNMFNFSL RQSKHLFQIL 
       370        380        390        400        410        420 
MECMVHKDSI TIFDADSEEH QDLDLAILTA LLKGTSLSIS EQLNLAMAWD RMDIAKKHIL 
       430        440        450        460        470        480 
TYGQHWKPGA LEQAMLDALV MDRVDFVKLL IENGVNLHRF LTIPRLEELY NTKQGPTNKF 
       490        500        510        520        530        540 
LRHLVQDVKQ HTLLSSYRIT LIDIGLVIEY LIGGAYRSSY TRKSFRILYN NLYRKHKSVS 
       550        560        570        580        590        600 
SFAQGLSQHS LHQRHSLRNR KESSESTLHS QFFRTAQPYK SKEKPEDSQK SKKKSKERQS 
       610        620        630        640        650        660 
LSEEPEAAGF IYPYNDLLVW AVLMKRQNMA MFFWQHGEEA TVKAVIASIL YRAMAREAKE 
       670        680        690        700        710        720 
SNMVDDTSEE LKNYSEQFGQ LALDVLEKAF KQNEPMAMKL LTYELKNWSN STCLKLAVSG 
       730        740        750        760        770        780 
GLRPFVSHSC TQMLLTDMWM GRLKMRKNSW LKIIISILLP PMILTLEFKS KAEMSHVPQS 
       790        800        810        820        830        840 
QDFQFTWNYS DQGLSNTKES ACVKDYDLER GPDEKPDEPL HLDLRNVPQS LPWTRRVYEF 
       850        860        870        880        890        900 
YSAPFVKFWF YTMAYLAFLM LFTYTVLVEM QPQPSVHEWL VIIYIFTNAI EKVREICISE 
       910        920        930        940        950        960 
PSKFKQKVKM WLSEYWNLME TVAIGLFAVG FGLRWGHPPL QTAGRLIYCI DIIFWFSRLM 
       970        980        990       1000       1010       1020 
DFFAVNQHAG PYVTMIAKMA ANMFYIVIIM AIVLLSFGVA RKAILSPKEP PSWRLARDIV 
      1030       1040       1050       1060       1070       1080 
FEPYWMMYGE VYASDIDVCS NETSCPPGSF LTPFLQAVYL FVQYIIMVNL LIACFNNIYL 
      1090       1100       1110       1120       1130       1140 
DIKSISNKLW KYNRYRYIMT YHQKPWLPPP FILLNHLCLL LRGLCCRPAP QDQEEGDGGL 
      1150       1160       1170       1180       1190       1200 
KLYLTKDDLK KLHDFEEQCV EKYFHEKTEG LNCSFEEQIR MTSERVSEMF FQLKEMNEKV 
      1210       1220       1230       1240       1250       1260 
SFIKDSLLSL DSQVGHLQDL SAITVDTLKV LSAVDTLQED EILLANRKHS TCRKRPHSWT 
      1270       1280       1290       1300       1310       1320 
NVICAKVLSD MESCGKKKLQ YYSMPPSLLR SLARSQLPPS VQRGALVEVT HSKREASHVR 
      1330       1340       1350       1360       1370       1380 
EEQEEREMEQ RTTASGISHV RQAHSKYGQF LLVPSSGKQV PLSLETPPHL FRSSEEAGID 
      1390       1400       1410       1420       1430       1440 
GLVLEHIHQS DLTTHLPQQT PAASHQALVA EHKDQHEAVT QMSDKPAKAE QDLLAFSGTP 
      1450       1460       1470       1480       1490       1500 
APMTVTSLPS RAISMQDEGG YVNWAFSEND ETGVFSFKKK WKTCLASTCN SDSNPGGDYF 
      1510       1520       1530       1540       1550       1560 
LHTGGRSGLD NSRRLAQSCE CPAGPWTQAR RSFWINPLCR DKALIKSHSF RFHKEEKLRK 
      1570       1580       1590       1600       1610       1620 
TWKNNSHSKS LETRSTWLKA KLLTKTRSLS KKKRKTQGLQ VPVITVNACY QSDQLNAEPG 
      1630       1640       1650       1660       1670       1680 
ETNTTEEFSK KWLSVSNFSQ IGLEPYIYQK MKMKEIKRHT TQASDHLRQP QENRDKTPTW 
      1690       1700       1710       1720       1730       1740 
NSGSTSLSRS FLTRSPNEVH KISTSLKSPQ EPHHHYSAIE RNNLMRLSQT IPFTPIQLFT 
      1750       1760       1770       1780       1790       1800 
GEEVTIYKLE ESSPLTLDKS MSSWSQHGRA AMIQVLSQEE MDGGLRKAMR VISTWSEDDV 
      1810       1820       1830       1840       1850       1860 
LKPGQVFIVK SFLPEVVQTW YKIFQESTVL HLCLREIQQQ RAAQKLIYTF NQVKPQTIPY 
      1870       1880       1890       1900       1910       1920 
TPRFLEVSLV YCHSANQWLT IEKYMTGEFR KYNNNNGDEI APTNTLEELM LAFSHWTYEY 
      1930       1940       1950       1960       1970       1980 
TRGELLVLDL QGVGENLTDP SVIKPEDKQS RGMVFGPANL GEDAIRSFIA KHRCNSCCGK 
      1990       2000       2010       2020    
LRLPDLKRND YSLSRTHCNL GFGQTIEPTE ELPERDKNRS SLEDHTRL

Isoforms



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8CIR4-1-unknown MQVKKS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...DHTRL 2028 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)