TopFIND 4.0

Q8CIV2: Membralin

General Information

Protein names
- Membralin
- Transmembrane protein 259
Gene names Tmem259
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8CIV2

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSEHAAAPGP GPNGGGGGGA APVRGPRGPN LNPNPLINVR DRLFHALFFK MAVTYSRLFP 
        70         80         90        100        110        120 
PAFRRLFEFF VLLKALFVLF VLAYIHIVFS RSPINCLEHV RDRWPREGVL RVEVRHNSSR 
       130        140        150        160        170        180 
APVILQFCDG GLGGLELEPG GLELEEEELT VEMFTNSSIK FELDIEPKVF KPQSGADALN 
       190        200        210        220        230        240 
DSQDFPFPET PAKVWPQDEY IVEYSLEYGF LRLSQATRQR LSIPVMVVTL DPTRDQCFGD 
       250        260        270        280        290        300 
RFSRLLLDEF LGYDDILMSS VKGLAENEEN KGFLRNVVSG EHYRFVSMWM ARTSYLAAFV 
       310        320        330        340        350        360 
IMVIFTLSVS MLLRYSHHQI FVFIVDLLQM LEMNMAIAFP AAPLLTVILA LVGMEAIMSE 
       370        380        390        400        410        420 
FFNDTTTAFY IILTVWLADQ YDAICCHTNT SKRHWLRFFY LYHFAFYAYH YRFNGQYSSL 
       430        440        450        460        470        480 
ALVTSWLFIQ HSMIYFFHHY ELPAILQQIR IQEMLLQTPP LGPGTPTALP DDLNNNSGSP 
       490        500        510        520        530        540 
ATPDPSPPLA LGPSSSPAPT GGASGPGSLG AGASVSGSDL GWVAETAAII SDASFLSGLS 
       550        560        570    
ASLLERRPTA PSTPDSSRPD PGVPLEDAPA PAGS

Isoforms

- Isoform 2 of Membralin

Sequence View

        10         20         30         40         50         60 
MSEHAAAPGP GPNGGGGGGA APVRGPRGPN LNPNPLINVR DRLFHALFFK MAVTYSRLFP 
        70         80         90        100        110        120 
PAFRRLFEFF VLLKALFVLF VLAYIHIVFS RSPINCLEHV RDRWPREGVL RVEVRHNSSR 
       130        140        150        160        170        180 
APVILQFCDG GLGGLELEPG GLELEEEELT VEMFTNSSIK FELDIEPKVF KPQSGADALN 
       190        200        210        220        230        240 
DSQDFPFPET PAKVWPQDEY IVEYSLEYGF LRLSQATRQR LSIPVMVVTL DPTRDQCFGD 
       250        260        270        280        290        300 
RFSRLLLDEF LGYDDILMSS VKGLAENEEN KGFLRNVVSG EHYRFVSMWM ARTSYLAAFV 
       310        320        330        340        350        360 
IMVIFTLSVS MLLRYSHHQI FVFIVDLLQM LEMNMAIAFP AAPLLTVILA LVGMEAIMSE 
       370        380        390        400        410        420 
FFNDTTTAFY IILTVWLADQ YDAICCHTNT SKRHWLRFFY LYHFAFYAYH YRFNGQYSSL 
       430        440        450        460        470        480 
ALVTSWLFIQ HSMIYFFHHY ELPAILQQIR IQEMLLQTPP LGPGTPTALP DDLNNNSGSP 
       490        500        510        520        530        540 
ATPDPSPPLA LGPSSSPAPT GGASGPGSLG AGASVSGSDL GWVAETAAII SDASFLSGLS 
       550        560        570    
ASLLERRPTA PSTPDSSRPD PGVPLEDAPA PAGS



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...APAGS 574 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...APAGS 574 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt76196

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)