Q8CJ40: Rootletin
| Protein names | - Rootletin - Ciliary rootlet coiled-coil protein |
|---|---|
| Gene names | Crocc |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q8CJ40 |
2
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSLGLAGSLQ AQLALEIVIQ SLENCVLGPN QEKSLSVQNR VQDFQGASLL VCAREVIASN
70 80 90 100 110 120
LSRPETPAPL QVPEMASLLS LQEENQLLQQ ELSRVEDLLA QSRAERDELA IKYNAVNERL
130 140 150 160 170 180
EQAVRLETGE LEAQEPRGLV RQSVELRRQL QEEQSSYRRK LQAYQEGQQR QAQLVQRLQA
190 200 210 220 230 240
KILQYKKQCS ELEKQLMDRS TELEQQRLRD TEHSQDLDSA LLRLEEEQQR SASLAQVNAM
250 260 270 280 290 300
LREQLDQANL ANQALSEDIR KVTSDWTRSC KELEQREAVW RREEESFNTY FSSEHSRLLR
310 320 330 340 350 360
LWRQVMGLRR QASEVKMGTE RDLLQLGGEL VRTSRAVQEL GLGLSASLHR AESKAEAALE
370 380 390 400 410 420
KQKLLQAQLE EQLQAKLLRE KDLAQLQVQS DLDKADLSAR VTELALSVEH LQNQNSEKDQ
430 440 450 460 470 480
VNRTLSDKLE ALESLRLQEQ TTLDTEDGEG LQQTLRDLAQ AALSDTESGV QLSSSERTAD
490 500 510 520 530 540
TSDGSLRGFS GQRTPTPPRH SPGRGRSPRR GLSPACSDSS TLTLIHSALH KRQLQVQDMR
550 560 570 580 590 600
GRYEASQELL GSVRKQLSDS EGERRGLEEQ LQRLRDQTAA SAQAQEDAQR EAQRLRSANE
610 620 630 640 650 660
LLSREKGNLT HSLQVTQQQA KELRQELEKL QAAQEELKRQ HNQLEDAQED SVQEGARARR
670 680 690 700 710 720
ELERSHRQLE QLEVKRSGLT KELVEVREAL SCAILQRDVL QTEKAEVAEA LTKAEAGRAQ
730 740 750 760 770 780
LELSLTKLRA EEASLRDSLS KMSALNESLA QDKLELNRLI AQLEEEKVAL LGRQQQAEHA
790 800 810 820 830 840
TTMAVEKQEL LEQLRLEQEV ERQGLQGSLC VAEQAREALE QQILVLRSER SHLQEQLAQL
850 860 870 880 890 900
SRQLSGRDQE LEQALRESQR QVEALERAAR EKEAMAKERA GLAVKLAAAE REGRTLSEEA
910 920 930 940 950 960
IRLRLEKEAL ESSLFDVQRQ LAQLEARREQ LEADSQALLL AKETLTGELA GLRQQVTSTE
970 980 990 1000 1010 1020
EKAALDKELM TQKLVQAERE AQASLREQRA AHEEDLQRLQ HEKEAAWREL QAERAQLQGQ
1030 1040 1050 1060 1070 1080
LQQEREELLA RMEAEKEELS KEIAALQQER DEGLLLAESE KQQALSLKES EKTALSEKLM
1090 1100 1110 1120 1130 1140
GTRHSLAAIS LEMERQKRDA QSRQEQDRNT LNALTSELRD LRAQLEEATA AHAQTVKELE
1150 1160 1170 1180 1190 1200
ERTGNLGRQR EACMREAEEL RTQLRVLEDT RDGLRRELLE AQRKGRDSQD SSEAHRQEAS
1210 1220 1230 1240 1250 1260
ELRRSLSEGA KEREALRRSN EELRSAVKKA ESERISLKLA NEDKEQKLAL LEEARVSVAK
1270 1280 1290 1300 1310 1320
EAGELRASLQ EVERSRLEAR RELQELRRQM KTLDSDNGRL GRELADLQGR LALGERTEKE
1330 1340 1350 1360 1370 1380
SRREALGLRQ RLLKGESSLE ALKQELQGSQ RKLQEQEAEF RARERGLLGS LEEARGAEKR
1390 1400 1410 1420 1430 1440
LLDSARSLEL RLEAVRAETS ELGLRLSAAE GRAQGLEVEL ARVEAQRRVA EAQLGGLRSA
1450 1460 1470 1480 1490 1500
LRRGLGLGRV SSSPAREAPA GGSGDGLSSP SPLEYSPRSQ PPSPGLIASP APPDLDPEAV
1510 1520 1530 1540 1550 1560
RDALRDFLQE LRSAQRERDE LKVQTSTLSQ QLVEMEAERD HAASRAKQLQ KAVAESEEAW
1570 1580 1590 1600 1610 1620
RSADRRLSGA QAELALQEES VRRSKRECRA TLDQMAVLER SLQATESELR ASQEKVSKMK
1630 1640 1650 1660 1670 1680
ATEAKLESDK RRLKEVLDAS ESRSIKLELQ RRALEGELQR SRLGLGDREA HAQALQDRVD
1690 1700 1710 1720 1730 1740
SLQRQVADSE VKAGTLQLTV ERLSGALAKV EESEGNLRSK VQSLTDALTQ SSASLSSTQD
1750 1760 1770 1780 1790 1800
KNLHLQKALS TCEHDRQVLQ ERLDAARQAL SEARRQSSSL GEQVQTLRGE LASLELQRGD
1810 1820 1830 1840 1850 1860
AEGQLQQLQQ ALRQRQEGEA MALRSVQKLQ EERRLLQERL GSLQRALAQL EAEKRDLERS
1870 1880 1890 1900 1910 1920
ALQFDKDRVA LRKTLDKVER EKLRSHEDTL RLNAERGRLD RTLTGAELDL AEAQQQIQHL
1930 1940 1950 1960 1970 1980
EAQVDVALEG NHNPVQPEAG EQQLELQQEV ERLRSAQVQT ERTLEARERA HRQRVSGLEE
1990 2000
QVSTLKAQLH QELRRSSASV SLPPGTPEK
Isoforms
- Isoform 2 of Rootletin - Isoform 3 of RootletinSequence View
10 20 30 40 50 60
MSLGLAGSLQ AQLALEIVIQ SLENCVLGPN QEKSLSVQNR VQDFQGASLL VCAREVIASN
70 80 90 100 110 120
LSRPETPAPL QVPEMASLLS LQEENQLLQQ ELSRVEDLLA QSRAERDELA IKYNAVNERL
130 140 150 160 170 180
EQAVRLETGE LEAQEPRGLV RQSVELRRQL QEEQSSYRRK LQAYQEGQQR QAQLVQRLQA
190 200 210 220 230 240
KILQYKKQCS ELEKQLMDRS TELEQQRLRD TEHSQDLDSA LLRLEEEQQR SASLAQVNAM
250 260 270 280 290 300
LREQLDQANL ANQALSEDIR KVTSDWTRSC KELEQREAVW RREEESFNTY FSSEHSRLLR
310 320 330 340 350 360
LWRQVMGLRR QASEVKMGTE RDLLQLGGEL VRTSRAVQEL GLGLSASLHR AESKAEAALE
370 380 390 400 410 420
KQKLLQAQLE EQLQAKLLRE KDLAQLQVQS DLDKADLSAR VTELALSVEH LQNQNSEKDQ
430 440 450 460 470 480
VNRTLSDKLE ALESLRLQEQ TTLDTEDGEG LQQTLRDLAQ AALSDTESGV QLSSSERTAD
490 500 510 520 530 540
TSDGSLRGFS GQRTPTPPRH SPGRGRSPRR GLSPACSDSS TLTLIHSALH KRQLQVQDMR
550 560 570 580 590 600
GRYEASQELL GSVRKQLSDS EGERRGLEEQ LQRLRDQTAA SAQAQEDAQR EAQRLRSANE
610 620 630 640 650 660
LLSREKGNLT HSLQVTQQQA KELRQELEKL QAAQEELKRQ HNQLEDAQED SVQEGARARR
670 680 690 700 710 720
ELERSHRQLE QLEVKRSGLT KELVEVREAL SCAILQRDVL QTEKAEVAEA LTKAEAGRAQ
730 740 750 760 770 780
LELSLTKLRA EEASLRDSLS KMSALNESLA QDKLELNRLI AQLEEEKVAL LGRQQQAEHA
790 800 810 820 830 840
TTMAVEKQEL LEQLRLEQEV ERQGLQGSLC VAEQAREALE QQILVLRSER SHLQEQLAQL
850 860 870 880 890 900
SRQLSGRDQE LEQALRESQR QVEALERAAR EKEAMAKERA GLAVKLAAAE REGRTLSEEA
910 920 930 940 950 960
IRLRLEKEAL ESSLFDVQRQ LAQLEARREQ LEADSQALLL AKETLTGELA GLRQQVTSTE
970 980 990 1000 1010 1020
EKAALDKELM TQKLVQAERE AQASLREQRA AHEEDLQRLQ HEKEAAWREL QAERAQLQGQ
1030 1040 1050 1060 1070 1080
LQQEREELLA RMEAEKEELS KEIAALQQER DEGLLLAESE KQQALSLKES EKTALSEKLM
1090 1100 1110 1120 1130 1140
GTRHSLAAIS LEMERQKRDA QSRQEQDRNT LNALTSELRD LRAQLEEATA AHAQTVKELE
1150 1160 1170 1180 1190 1200
ERTGNLGRQR EACMREAEEL RTQLRVLEDT RDGLRRELLE AQRKGRDSQD SSEAHRQEAS
1210 1220 1230 1240 1250 1260
ELRRSLSEGA KEREALRRSN EELRSAVKKA ESERISLKLA NEDKEQKLAL LEEARVSVAK
1270 1280 1290 1300 1310 1320
EAGELRASLQ EVERSRLEAR RELQELRRQM KTLDSDNGRL GRELADLQGR LALGERTEKE
1330 1340 1350 1360 1370 1380
SRREALGLRQ RLLKGESSLE ALKQELQGSQ RKLQEQEAEF RARERGLLGS LEEARGAEKR
1390 1400 1410 1420 1430 1440
LLDSARSLEL RLEAVRAETS ELGLRLSAAE GRAQGLEVEL ARVEAQRRVA EAQLGGLRSA
1450 1460 1470 1480 1490 1500
LRRGLGLGRV SSSPAREAPA GGSGDGLSSP SPLEYSPRSQ PPSPGLIASP APPDLDPEAV
1510 1520 1530 1540 1550 1560
RDALRDFLQE LRSAQRERDE LKVQTSTLSQ QLVEMEAERD HAASRAKQLQ KAVAESEEAW
1570 1580 1590 1600 1610 1620
RSADRRLSGA QAELALQEES VRRSKRECRA TLDQMAVLER SLQATESELR ASQEKVSKMK
1630 1640 1650 1660 1670 1680
ATEAKLESDK RRLKEVLDAS ESRSIKLELQ RRALEGELQR SRLGLGDREA HAQALQDRVD
1690 1700 1710 1720 1730 1740
SLQRQVADSE VKAGTLQLTV ERLSGALAKV EESEGNLRSK VQSLTDALTQ SSASLSSTQD
1750 1760 1770 1780 1790 1800
KNLHLQKALS TCEHDRQVLQ ERLDAARQAL SEARRQSSSL GEQVQTLRGE LASLELQRGD
1810 1820 1830 1840 1850 1860
AEGQLQQLQQ ALRQRQEGEA MALRSVQKLQ EERRLLQERL GSLQRALAQL EAEKRDLERS
1870 1880 1890 1900 1910 1920
ALQFDKDRVA LRKTLDKVER EKLRSHEDTL RLNAERGRLD RTLTGAELDL AEAQQQIQHL
1930 1940 1950 1960 1970 1980
EAQVDVALEG NHNPVQPEAG EQQLELQQEV ERLRSAQVQT ERTLEARERA HRQRVSGLEE
1990 2000
QVSTLKAQLH QELRRSSASV SLPPGTPEK
10 20 30 40 50 60
MSLGLAGSLQ AQLALEIVIQ SLENCVLGPN QEKSLSVQNR VQDFQGASLL VCAREVIASN
70 80 90 100 110 120
LSRPETPAPL QVPEMASLLS LQEENQLLQQ ELSRVEDLLA QSRAERDELA IKYNAVNERL
130 140 150 160 170 180
EQAVRLETGE LEAQEPRGLV RQSVELRRQL QEEQSSYRRK LQAYQEGQQR QAQLVQRLQA
190 200 210 220 230 240
KILQYKKQCS ELEKQLMDRS TELEQQRLRD TEHSQDLDSA LLRLEEEQQR SASLAQVNAM
250 260 270 280 290 300
LREQLDQANL ANQALSEDIR KVTSDWTRSC KELEQREAVW RREEESFNTY FSSEHSRLLR
310 320 330 340 350 360
LWRQVMGLRR QASEVKMGTE RDLLQLGGEL VRTSRAVQEL GLGLSASLHR AESKAEAALE
370 380 390 400 410 420
KQKLLQAQLE EQLQAKLLRE KDLAQLQVQS DLDKADLSAR VTELALSVEH LQNQNSEKDQ
430 440 450 460 470 480
VNRTLSDKLE ALESLRLQEQ TTLDTEDGEG LQQTLRDLAQ AALSDTESGV QLSSSERTAD
490 500 510 520 530 540
TSDGSLRGFS GQRTPTPPRH SPGRGRSPRR GLSPACSDSS TLTLIHSALH KRQLQVQDMR
550 560 570 580 590 600
GRYEASQELL GSVRKQLSDS EGERRGLEEQ LQRLRDQTAA SAQAQEDAQR EAQRLRSANE
610 620 630 640 650 660
LLSREKGNLT HSLQVTQQQA KELRQELEKL QAAQEELKRQ HNQLEDAQED SVQEGARARR
670 680 690 700 710 720
ELERSHRQLE QLEVKRSGLT KELVEVREAL SCAILQRDVL QTEKAEVAEA LTKAEAGRAQ
730 740 750 760 770 780
LELSLTKLRA EEASLRDSLS KMSALNESLA QDKLELNRLI AQLEEEKVAL LGRQQQAEHA
790 800 810 820 830 840
TTMAVEKQEL LEQLRLEQEV ERQGLQGSLC VAEQAREALE QQILVLRSER SHLQEQLAQL
850 860 870 880 890 900
SRQLSGRDQE LEQALRESQR QVEALERAAR EKEAMAKERA GLAVKLAAAE REGRTLSEEA
910 920 930 940 950 960
IRLRLEKEAL ESSLFDVQRQ LAQLEARREQ LEADSQALLL AKETLTGELA GLRQQVTSTE
970 980 990 1000 1010 1020
EKAALDKELM TQKLVQAERE AQASLREQRA AHEEDLQRLQ HEKEAAWREL QAERAQLQGQ
1030 1040 1050 1060 1070 1080
LQQEREELLA RMEAEKEELS KEIAALQQER DEGLLLAESE KQQALSLKES EKTALSEKLM
1090 1100 1110 1120 1130 1140
GTRHSLAAIS LEMERQKRDA QSRQEQDRNT LNALTSELRD LRAQLEEATA AHAQTVKELE
1150 1160 1170 1180 1190 1200
ERTGNLGRQR EACMREAEEL RTQLRVLEDT RDGLRRELLE AQRKGRDSQD SSEAHRQEAS
1210 1220 1230 1240 1250 1260
ELRRSLSEGA KEREALRRSN EELRSAVKKA ESERISLKLA NEDKEQKLAL LEEARVSVAK
1270 1280 1290 1300 1310 1320
EAGELRASLQ EVERSRLEAR RELQELRRQM KTLDSDNGRL GRELADLQGR LALGERTEKE
1330 1340 1350 1360 1370 1380
SRREALGLRQ RLLKGESSLE ALKQELQGSQ RKLQEQEAEF RARERGLLGS LEEARGAEKR
1390 1400 1410 1420 1430 1440
LLDSARSLEL RLEAVRAETS ELGLRLSAAE GRAQGLEVEL ARVEAQRRVA EAQLGGLRSA
1450 1460 1470 1480 1490 1500
LRRGLGLGRV SSSPAREAPA GGSGDGLSSP SPLEYSPRSQ PPSPGLIASP APPDLDPEAV
1510 1520 1530 1540 1550 1560
RDALRDFLQE LRSAQRERDE LKVQTSTLSQ QLVEMEAERD HAASRAKQLQ KAVAESEEAW
1570 1580 1590 1600 1610 1620
RSADRRLSGA QAELALQEES VRRSKRECRA TLDQMAVLER SLQATESELR ASQEKVSKMK
1630 1640 1650 1660 1670 1680
ATEAKLESDK RRLKEVLDAS ESRSIKLELQ RRALEGELQR SRLGLGDREA HAQALQDRVD
1690 1700 1710 1720 1730 1740
SLQRQVADSE VKAGTLQLTV ERLSGALAKV EESEGNLRSK VQSLTDALTQ SSASLSSTQD
1750 1760 1770 1780 1790 1800
KNLHLQKALS TCEHDRQVLQ ERLDAARQAL SEARRQSSSL GEQVQTLRGE LASLELQRGD
1810 1820 1830 1840 1850 1860
AEGQLQQLQQ ALRQRQEGEA MALRSVQKLQ EERRLLQERL GSLQRALAQL EAEKRDLERS
1870 1880 1890 1900 1910 1920
ALQFDKDRVA LRKTLDKVER EKLRSHEDTL RLNAERGRLD RTLTGAELDL AEAQQQIQHL
1930 1940 1950 1960 1970 1980
EAQVDVALEG NHNPVQPEAG EQQLELQQEV ERLRSAQVQT ERTLEARERA HRQRVSGLEE
1990 2000
QVSTLKAQLH QELRRSSASV SLPPGTPEK
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q8CJ40-1-unknown | MSLGLA... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q8CJ40-1-unknown | MSLGLA... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt71781 | |||
| Q8CJ40-75-unknown | MASLLS... | 75 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt71780 | |||
| Q8CJ40-75-unknown | MASLLS... | 75 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt101580 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...GTPEK | 2009 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...GTPEK | 2009 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt67398 | |||
| ...GTPEK | 2009 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt67399 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|