Q8CJG0: Protein argonaute-2 {ECO:0000255|HAMAP-Rule:MF_03031}
Protein names | - Protein argonaute-2 {ECO:0000255|HAMAP-Rule:MF_03031} - Argonaute2 {ECO:0000255|HAMAP-Rule:MF_03031} - mAgo2 - 3.1.26.n2 {ECO:0000255|HAMAP-Rule:MF_03031} - Argonaute RISC catalytic component 2 - Eukaryotic translation initiation factor 2C 2 {ECO:0000255|HAMAP-Rule:MF_03031} - eIF-2C 2 {ECO:0000255|HAMAP-Rule:MF_03031} - eIF2C 2 {ECO:0000255|HAMAP-Rule:MF_03031} - Piwi/argonaute family protein meIF2C2 - Protein slicer {ECO:0000255|HAMAP-Rule:MF_03031} |
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Gene names | Ago2 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q8CJG0 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MYSGAGPVLA SPAPTTSPIP GYAFKPPPRP DFGTTGRTIK LQANFFEMDI PKIDIYHYEL
70 80 90 100 110 120
DIKPEKCPRR VNREIVEHMV QHFKTQIFGD RKPVFDGRKN LYTAMPLPIG RDKVELEVTL
130 140 150 160 170 180
PGEGKDRIFK VSIKWVSCVS LQALHDALSG RLPSVPFETI QALDVVMRHL PSMRYTPVGR
190 200 210 220 230 240
SFFTASEGCS NPLGGGREVW FGFHQSVRPS LWKMMLNIDV SATAFYKAQP VIEFVCEVLD
250 260 270 280 290 300
FKSIEEQQKP LTDSQRVKFT KEIKGLKVEI THCGQMKRKY RVCNVTRRPA SHQTFPLQQE
310 320 330 340 350 360
SGQTVECTVA QYFKDRHKLV LRYPHLPCLQ VGQEQKHTYL PLEVCNIVAG QRCIKKLTDN
370 380 390 400 410 420
QTSTMIRATA RSAPDRQEEI SKLMRSASFN TDPYVREFGI MVKDEMTDVT GRVLQPPSIL
430 440 450 460 470 480
YGGRNKAIAT PVQGVWDMRN KQFHTGIEIK VWAIACFAPQ RQCTEVHLKS FTEQLRKISR
490 500 510 520 530 540
DAGMPIQGQP CFCKYAQGAD SVEPMFRHLK NTYAGLQLVV VILPGKTPVY AEVKRVGDTV
550 560 570 580 590 600
LGMATQCVQM KNVQRTTPQT LSNLCLKINV KLGGVNNILL PQGRPPVFQQ PVIFLGADVT
610 620 630 640 650 660
HPPAGDGKKP SIAAVVGSMD AHPNRYCATV RVQQHRQEII QDLAAMVREL LIQFYKSTRF
670 680 690 700 710 720
KPTRIIFYRD GVSEGQFQQV LHHELLAIRE ACIKLEKDYQ PGITFIVVQK RHHTRLFCTD
730 740 750 760 770 780
KNERVGKSGN IPAGTTVDTK ITHPTEFDFY LCSHAGIQGT SRPSHYHVLW DDNRFSSDEL
790 800 810 820 830 840
QILTYQLCHT YVRCTRSVSI PAPAYYAHLV AFRARYHLVD KEHDSAEGSH TSGQSNGRDH
850 860
QALAKAVQVH QDTLRTMYFA
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q8CJG0-1-unknown | MYSGAG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q8CJG0-548-unknown | VQMKNV... | 548 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30811 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...MATQCV | 547 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30811 | |||
...TMYFA | 860 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATE_MOUSE | 547 | TQCV.|.VQMK | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> AGO2_MOUSE @547 |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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