TopFIND 4.0

Q8IU57: Interferon lambda receptor 1

General Information

Protein names
- Interferon lambda receptor 1
- IFN-lambda receptor 1
- IFN-lambda-R1
- Cytokine receptor class-II member 12
- Cytokine receptor family 2 member 12
- CRF2-12
- Interleukin-28 receptor subunit alpha
- IL-28 receptor subunit alpha
- IL-28R-alpha
- IL-28RA
- Likely interleukin or cytokine receptor 2
- LICR2
Gene names IFNLR1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8IU57

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAGPERWGPL LLCLLQAAPG RPRLAPPQNV TLLSQNFSVY LTWLPGLGNP QDVTYFVAYQ 
        70         80         90        100        110        120 
SSPTRRRWRE VEECAGTKEL LCSMMCLKKQ DLYNKFKGRV RTVSPSSKSP WVESEYLDYL 
       130        140        150        160        170        180 
FEVEPAPPVL VLTQTEEILS ANATYQLPPC MPPLDLKYEV AFWKEGAGNK TLFPVTPHGQ 
       190        200        210        220        230        240 
PVQITLQPAA SEHHCLSART IYTFSVPKYS KFSKPTCFLL EVPEANWAFL VLPSLLILLL 
       250        260        270        280        290        300 
VIAAGGVIWK TLMGNPWFQR AKMPRALDFS GHTHPVATFQ PSRPESVNDL FLCPQKELTR 
       310        320        330        340        350        360 
GVRPTPRVRA PATQQTRWKK DLAEDEEEED EEDTEDGVSF QPYIEPPSFL GQEHQAPGHS 
       370        380        390        400        410        420 
EAGGVDSGRP RAPLVPSEGS SAWDSSDRSW ASTVDSSWDR AGSSGYLAEK GPGQGPGGDG 
       430        440        450        460        470        480 
HQESLPPPEF SKDSGFLEEL PEDNLSSWAT WGTLPPEPNL VPGGPPVSLQ TLTFCWESSP 
       490        500        510        520    
EEEEEARESE IEDSDAGSWG AESTQRTEDR GRTLGHYMAR 

Isoforms

- Isoform 2 of Interferon lambda receptor 1 - Isoform 3 of Interferon lambda receptor 1 - Isoform 4 of Interferon lambda receptor 1

Sequence View

        10         20         30         40         50         60 
MAGPERWGPL LLCLLQAAPG RPRLAPPQNV TLLSQNFSVY LTWLPGLGNP QDVTYFVAYQ 
        70         80         90        100        110        120 
SSPTRRRWRE VEECAGTKEL LCSMMCLKKQ DLYNKFKGRV RTVSPSSKSP WVESEYLDYL 
       130        140        150        160        170        180 
FEVEPAPPVL VLTQTEEILS ANATYQLPPC MPPLDLKYEV AFWKEGAGNK TLFPVTPHGQ 
       190        200        210        220        230        240 
PVQITLQPAA SEHHCLSART IYTFSVPKYS KFSKPTCFLL EVPEANWAFL VLPSLLILLL 
       250        260        270        280        290        300 
VIAAGGVIWK TLMGNPWFQR AKMPRALDFS GHTHPVATFQ PSRPESVNDL FLCPQKELTR 
       310        320        330        340        350        360 
GVRPTPRVRA PATQQTRWKK DLAEDEEEED EEDTEDGVSF QPYIEPPSFL GQEHQAPGHS 
       370        380        390        400        410        420 
EAGGVDSGRP RAPLVPSEGS SAWDSSDRSW ASTVDSSWDR AGSSGYLAEK GPGQGPGGDG 
       430        440        450        460        470        480 
HQESLPPPEF SKDSGFLEEL PEDNLSSWAT WGTLPPEPNL VPGGPPVSLQ TLTFCWESSP 
       490        500        510        520    
EEEEEARESE IEDSDAGSWG AESTQRTEDR GRTLGHYMAR          10         20         30         40         50         60 
MAGPERWGPL LLCLLQAAPG RPRLAPPQNV TLLSQNFSVY LTWLPGLGNP QDVTYFVAYQ 
        70         80         90        100        110        120 
SSPTRRRWRE VEECAGTKEL LCSMMCLKKQ DLYNKFKGRV RTVSPSSKSP WVESEYLDYL 
       130        140        150        160        170        180 
FEVEPAPPVL VLTQTEEILS ANATYQLPPC MPPLDLKYEV AFWKEGAGNK TLFPVTPHGQ 
       190        200        210        220        230        240 
PVQITLQPAA SEHHCLSART IYTFSVPKYS KFSKPTCFLL EVPEANWAFL VLPSLLILLL 
       250        260        270        280        290        300 
VIAAGGVIWK TLMGNPWFQR AKMPRALDFS GHTHPVATFQ PSRPESVNDL FLCPQKELTR 
       310        320        330        340        350        360 
GVRPTPRVRA PATQQTRWKK DLAEDEEEED EEDTEDGVSF QPYIEPPSFL GQEHQAPGHS 
       370        380        390        400        410        420 
EAGGVDSGRP RAPLVPSEGS SAWDSSDRSW ASTVDSSWDR AGSSGYLAEK GPGQGPGGDG 
       430        440        450        460        470        480 
HQESLPPPEF SKDSGFLEEL PEDNLSSWAT WGTLPPEPNL VPGGPPVSLQ TLTFCWESSP 
       490        500        510        520    
EEEEEARESE IEDSDAGSWG AESTQRTEDR GRTLGHYMAR          10         20         30         40         50         60 
MAGPERWGPL LLCLLQAAPG RPRLAPPQNV TLLSQNFSVY LTWLPGLGNP QDVTYFVAYQ 
        70         80         90        100        110        120 
SSPTRRRWRE VEECAGTKEL LCSMMCLKKQ DLYNKFKGRV RTVSPSSKSP WVESEYLDYL 
       130        140        150        160        170        180 
FEVEPAPPVL VLTQTEEILS ANATYQLPPC MPPLDLKYEV AFWKEGAGNK TLFPVTPHGQ 
       190        200        210        220        230        240 
PVQITLQPAA SEHHCLSART IYTFSVPKYS KFSKPTCFLL EVPEANWAFL VLPSLLILLL 
       250        260        270        280        290        300 
VIAAGGVIWK TLMGNPWFQR AKMPRALDFS GHTHPVATFQ PSRPESVNDL FLCPQKELTR 
       310        320        330        340        350        360 
GVRPTPRVRA PATQQTRWKK DLAEDEEEED EEDTEDGVSF QPYIEPPSFL GQEHQAPGHS 
       370        380        390        400        410        420 
EAGGVDSGRP RAPLVPSEGS SAWDSSDRSW ASTVDSSWDR AGSSGYLAEK GPGQGPGGDG 
       430        440        450        460        470        480 
HQESLPPPEF SKDSGFLEEL PEDNLSSWAT WGTLPPEPNL VPGGPPVSLQ TLTFCWESSP 
       490        500        510        520    
EEEEEARESE IEDSDAGSWG AESTQRTEDR GRTLGHYMAR 



Filter Information:


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Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HYMAR 520 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...HYMAR 520 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt73532

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)