TopFIND 4.0

Q8IUD6: E3 ubiquitin-protein ligase RNF135

General Information

Protein names
- E3 ubiquitin-protein ligase RNF135
- 2.3.2.27
- RIG-I E3 ubiquitin ligase
- REUL
- RING finger protein 135
- RING-type E3 ubiquitin transferase RNF135 {ECO:0000305}
- Riplet
Gene names RNF135
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8IUD6

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAGLGLGSAV PVWLAEDDLG CIICQGLLDW PATLPCGHSF CRHCLEALWG ARDARRWACP 
        70         80         90        100        110        120 
TCRQGAAQQP HLRKNTLLQD LADKYRRAAR EIQAGSDPAH CPCPGSSSLS SAAARPRRRP 
       130        140        150        160        170        180 
ELQRVAVEKS ITEVAQELTE LVEHLVDIVR SLQNQRPLSE SGPDNELSIL GKAFSSGVDL 
       190        200        210        220        230        240 
SMASPKLVTS DTAAGKIRDI LHDLEEIQEK LQESVTWKEA PEAQMQGELL EAPSSSSCPL 
       250        260        270        280        290        300 
PDQSHPALRR ASRFAQWAIH PTFNLKSLSC SLEVSKDSRT VTVSHRPQPY RWSCERFSTS 
       310        320        330        340        350        360 
QVLCSQALSS GKHYWEVDTR NCSHWAVGVA SWEMSRDQVL GRTMDSCCVE WKGTSQLSAW 
       370        380        390        400        410        420 
HMVKETVLGS DRPGVVGIWL NLEEGKLAFY SVDNQEKLLY ECTISASSPL YPAFWLYGLH 
       430    
PGNYLIIKQV KV

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase RNF135 - Isoform 3 of E3 ubiquitin-protein ligase RNF135

Sequence View

        10         20         30         40         50         60 
MAGLGLGSAV PVWLAEDDLG CIICQGLLDW PATLPCGHSF CRHCLEALWG ARDARRWACP 
        70         80         90        100        110        120 
TCRQGAAQQP HLRKNTLLQD LADKYRRAAR EIQAGSDPAH CPCPGSSSLS SAAARPRRRP 
       130        140        150        160        170        180 
ELQRVAVEKS ITEVAQELTE LVEHLVDIVR SLQNQRPLSE SGPDNELSIL GKAFSSGVDL 
       190        200        210        220        230        240 
SMASPKLVTS DTAAGKIRDI LHDLEEIQEK LQESVTWKEA PEAQMQGELL EAPSSSSCPL 
       250        260        270        280        290        300 
PDQSHPALRR ASRFAQWAIH PTFNLKSLSC SLEVSKDSRT VTVSHRPQPY RWSCERFSTS 
       310        320        330        340        350        360 
QVLCSQALSS GKHYWEVDTR NCSHWAVGVA SWEMSRDQVL GRTMDSCCVE WKGTSQLSAW 
       370        380        390        400        410        420 
HMVKETVLGS DRPGVVGIWL NLEEGKLAFY SVDNQEKLLY ECTISASSPL YPAFWLYGLH 
       430    
PGNYLIIKQV KV         10         20         30         40         50         60 
MAGLGLGSAV PVWLAEDDLG CIICQGLLDW PATLPCGHSF CRHCLEALWG ARDARRWACP 
        70         80         90        100        110        120 
TCRQGAAQQP HLRKNTLLQD LADKYRRAAR EIQAGSDPAH CPCPGSSSLS SAAARPRRRP 
       130        140        150        160        170        180 
ELQRVAVEKS ITEVAQELTE LVEHLVDIVR SLQNQRPLSE SGPDNELSIL GKAFSSGVDL 
       190        200        210        220        230        240 
SMASPKLVTS DTAAGKIRDI LHDLEEIQEK LQESVTWKEA PEAQMQGELL EAPSSSSCPL 
       250        260        270        280        290        300 
PDQSHPALRR ASRFAQWAIH PTFNLKSLSC SLEVSKDSRT VTVSHRPQPY RWSCERFSTS 
       310        320        330        340        350        360 
QVLCSQALSS GKHYWEVDTR NCSHWAVGVA SWEMSRDQVL GRTMDSCCVE WKGTSQLSAW 
       370        380        390        400        410        420 
HMVKETVLGS DRPGVVGIWL NLEEGKLAFY SVDNQEKLLY ECTISASSPL YPAFWLYGLH 
       430    
PGNYLIIKQV KV



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8IUD6-1-unknown MAGLGL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8IUD6-1-unknown MAGLGL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt87895
    Q8IUD6-1-unknown MAGLGL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt87896

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KQVKV 432 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)