TopFIND 4.0

Q8IUF8: Ribosomal oxygenase 2 {ECO:0000312|HGNC:HGNC:19441}

General Information

Protein names
- Ribosomal oxygenase 2 {ECO:0000312|HGNC:HGNC:19441}
- 60S ribosomal protein L27a histidine hydroxylase
- Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA
- 1.14.11.-
- Histone lysine demethylase MINA
- MYC-induced nuclear antigen
- Mineral dust-induced gene protein
- Nucleolar protein 52
- Ribosomal oxygenase MINA
- ROX
Gene names MINA
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8IUF8

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPKKAKPTGS GKEEGPAPCK QMKLEAAGGP SALNFDSPSS LFESLISPIK TETFFKEFWE 
        70         80         90        100        110        120 
QKPLLIQRDD PALATYYGSL FKLTDLKSLC SRGMYYGRDV NVCRCVNGKK KVLNKDGKAH 
       130        140        150        160        170        180 
FLQLRKDFDQ KRATIQFHQP QRFKDELWRI QEKLECYFGS LVGSNVYITP AGSQGLPPHY 
       190        200        210        220        230        240 
DDVEVFILQL EGEKHWRLYH PTVPLAREYS VEAEERIGRP VHEFMLKPGD LLYFPRGTIH 
       250        260        270        280        290        300 
QADTPAGLAH STHVTISTYQ NNSWGDFLLD TISGLVFDTA KEDVELRTGI PRQLLLQVES 
       310        320        330        340        350        360 
TTVATRRLSG FLRTLADRLE GTKELLSSDM KKDFIMHRLP PYSAGDGAEL STPGGKLPRL 
       370        380        390        400        410        420 
DSVVRLQFKD HIVLTVLPDQ DQSDEAQEKM VYIYHSLKNS RETHMMGNEE ETEFHGLRFP 
       430        440        450        460    
LSHLDALKQI WNSPAISVKD LKLTTDEEKE SLVLSLWTEC LIQVV

Isoforms

- Isoform 2 of Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA - Isoform 3 of Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA - Isoform 4 of Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA - Isoform 2 of Ribosomal oxygenase 2 - Isoform 3 of Ribosomal oxygenase 2 - Isoform 4 of Ribosomal oxygenase 2

Sequence View

        10         20         30         40         50         60 
MPKKAKPTGS GKEEGPAPCK QMKLEAAGGP SALNFDSPSS LFESLISPIK TETFFKEFWE 
        70         80         90        100        110        120 
QKPLLIQRDD PALATYYGSL FKLTDLKSLC SRGMYYGRDV NVCRCVNGKK KVLNKDGKAH 
       130        140        150        160        170        180 
FLQLRKDFDQ KRATIQFHQP QRFKDELWRI QEKLECYFGS LVGSNVYITP AGSQGLPPHY 
       190        200        210        220        230        240 
DDVEVFILQL EGEKHWRLYH PTVPLAREYS VEAEERIGRP VHEFMLKPGD LLYFPRGTIH 
       250        260        270        280        290        300 
QADTPAGLAH STHVTISTYQ NNSWGDFLLD TISGLVFDTA KEDVELRTGI PRQLLLQVES 
       310        320        330        340        350        360 
TTVATRRLSG FLRTLADRLE GTKELLSSDM KKDFIMHRLP PYSAGDGAEL STPGGKLPRL 
       370        380        390        400        410        420 
DSVVRLQFKD HIVLTVLPDQ DQSDEAQEKM VYIYHSLKNS RETHMMGNEE ETEFHGLRFP 
       430        440        450        460    
LSHLDALKQI WNSPAISVKD LKLTTDEEKE SLVLSLWTEC LIQVV         10         20         30         40         50         60 
MPKKAKPTGS GKEEGPAPCK QMKLEAAGGP SALNFDSPSS LFESLISPIK TETFFKEFWE 
        70         80         90        100        110        120 
QKPLLIQRDD PALATYYGSL FKLTDLKSLC SRGMYYGRDV NVCRCVNGKK KVLNKDGKAH 
       130        140        150        160        170        180 
FLQLRKDFDQ KRATIQFHQP QRFKDELWRI QEKLECYFGS LVGSNVYITP AGSQGLPPHY 
       190        200        210        220        230        240 
DDVEVFILQL EGEKHWRLYH PTVPLAREYS VEAEERIGRP VHEFMLKPGD LLYFPRGTIH 
       250        260        270        280        290        300 
QADTPAGLAH STHVTISTYQ NNSWGDFLLD TISGLVFDTA KEDVELRTGI PRQLLLQVES 
       310        320        330        340        350        360 
TTVATRRLSG FLRTLADRLE GTKELLSSDM KKDFIMHRLP PYSAGDGAEL STPGGKLPRL 
       370        380        390        400        410        420 
DSVVRLQFKD HIVLTVLPDQ DQSDEAQEKM VYIYHSLKNS RETHMMGNEE ETEFHGLRFP 
       430        440        450        460    
LSHLDALKQI WNSPAISVKD LKLTTDEEKE SLVLSLWTEC LIQVV         10         20         30         40         50         60 
MPKKAKPTGS GKEEGPAPCK QMKLEAAGGP SALNFDSPSS LFESLISPIK TETFFKEFWE 
        70         80         90        100        110        120 
QKPLLIQRDD PALATYYGSL FKLTDLKSLC SRGMYYGRDV NVCRCVNGKK KVLNKDGKAH 
       130        140        150        160        170        180 
FLQLRKDFDQ KRATIQFHQP QRFKDELWRI QEKLECYFGS LVGSNVYITP AGSQGLPPHY 
       190        200        210        220        230        240 
DDVEVFILQL EGEKHWRLYH PTVPLAREYS VEAEERIGRP VHEFMLKPGD LLYFPRGTIH 
       250        260        270        280        290        300 
QADTPAGLAH STHVTISTYQ NNSWGDFLLD TISGLVFDTA KEDVELRTGI PRQLLLQVES 
       310        320        330        340        350        360 
TTVATRRLSG FLRTLADRLE GTKELLSSDM KKDFIMHRLP PYSAGDGAEL STPGGKLPRL 
       370        380        390        400        410        420 
DSVVRLQFKD HIVLTVLPDQ DQSDEAQEKM VYIYHSLKNS RETHMMGNEE ETEFHGLRFP 
       430        440        450        460    
LSHLDALKQI WNSPAISVKD LKLTTDEEKE SLVLSLWTEC LIQVV         10         20         30         40         50         60 
MPKKAKPTGS GKEEGPAPCK QMKLEAAGGP SALNFDSPSS LFESLISPIK TETFFKEFWE 
        70         80         90        100        110        120 
QKPLLIQRDD PALATYYGSL FKLTDLKSLC SRGMYYGRDV NVCRCVNGKK KVLNKDGKAH 
       130        140        150        160        170        180 
FLQLRKDFDQ KRATIQFHQP QRFKDELWRI QEKLECYFGS LVGSNVYITP AGSQGLPPHY 
       190        200        210        220        230        240 
DDVEVFILQL EGEKHWRLYH PTVPLAREYS VEAEERIGRP VHEFMLKPGD LLYFPRGTIH 
       250        260        270        280        290        300 
QADTPAGLAH STHVTISTYQ NNSWGDFLLD TISGLVFDTA KEDVELRTGI PRQLLLQVES 
       310        320        330        340        350        360 
TTVATRRLSG FLRTLADRLE GTKELLSSDM KKDFIMHRLP PYSAGDGAEL STPGGKLPRL 
       370        380        390        400        410        420 
DSVVRLQFKD HIVLTVLPDQ DQSDEAQEKM VYIYHSLKNS RETHMMGNEE ETEFHGLRFP 
       430        440        450        460    
LSHLDALKQI WNSPAISVKD LKLTTDEEKE SLVLSLWTEC LIQVV         10         20         30         40         50         60 
MPKKAKPTGS GKEEGPAPCK QMKLEAAGGP SALNFDSPSS LFESLISPIK TETFFKEFWE 
        70         80         90        100        110        120 
QKPLLIQRDD PALATYYGSL FKLTDLKSLC SRGMYYGRDV NVCRCVNGKK KVLNKDGKAH 
       130        140        150        160        170        180 
FLQLRKDFDQ KRATIQFHQP QRFKDELWRI QEKLECYFGS LVGSNVYITP AGSQGLPPHY 
       190        200        210        220        230        240 
DDVEVFILQL EGEKHWRLYH PTVPLAREYS VEAEERIGRP VHEFMLKPGD LLYFPRGTIH 
       250        260        270        280        290        300 
QADTPAGLAH STHVTISTYQ NNSWGDFLLD TISGLVFDTA KEDVELRTGI PRQLLLQVES 
       310        320        330        340        350        360 
TTVATRRLSG FLRTLADRLE GTKELLSSDM KKDFIMHRLP PYSAGDGAEL STPGGKLPRL 
       370        380        390        400        410        420 
DSVVRLQFKD HIVLTVLPDQ DQSDEAQEKM VYIYHSLKNS RETHMMGNEE ETEFHGLRFP 
       430        440        450        460    
LSHLDALKQI WNSPAISVKD LKLTTDEEKE SLVLSLWTEC LIQVV         10         20         30         40         50         60 
MPKKAKPTGS GKEEGPAPCK QMKLEAAGGP SALNFDSPSS LFESLISPIK TETFFKEFWE 
        70         80         90        100        110        120 
QKPLLIQRDD PALATYYGSL FKLTDLKSLC SRGMYYGRDV NVCRCVNGKK KVLNKDGKAH 
       130        140        150        160        170        180 
FLQLRKDFDQ KRATIQFHQP QRFKDELWRI QEKLECYFGS LVGSNVYITP AGSQGLPPHY 
       190        200        210        220        230        240 
DDVEVFILQL EGEKHWRLYH PTVPLAREYS VEAEERIGRP VHEFMLKPGD LLYFPRGTIH 
       250        260        270        280        290        300 
QADTPAGLAH STHVTISTYQ NNSWGDFLLD TISGLVFDTA KEDVELRTGI PRQLLLQVES 
       310        320        330        340        350        360 
TTVATRRLSG FLRTLADRLE GTKELLSSDM KKDFIMHRLP PYSAGDGAEL STPGGKLPRL 
       370        380        390        400        410        420 
DSVVRLQFKD HIVLTVLPDQ DQSDEAQEKM VYIYHSLKNS RETHMMGNEE ETEFHGLRFP 
       430        440        450        460    
LSHLDALKQI WNSPAISVKD LKLTTDEEKE SLVLSLWTEC LIQVV



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8IUF8-1-unknown MPKKAK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8IUF8-1-unknown MPKKAK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt81139
    Q8IUF8-1-unknown MPKKAK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt81141

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)