TopFIND 4.0

Q8IUX4: DNA dC->dU-editing enzyme APOBEC-3F

General Information

Protein names
- DNA dC->dU-editing enzyme APOBEC-3F
- 3.5.4.38
- Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F
- A3F
Gene names APOBEC3F
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8IUX4

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKPHFRNTVE RMYRDTFSYN FYNRPILSRR NTVWLCYEVK TKGPSRPRLD AKIFRGQVYS 
        70         80         90        100        110        120 
QPEHHAEMCF LSWFCGNQLP AYKCFQITWF VSWTPCPDCV AKLAEFLAEH PNVTLTISAA 
       130        140        150        160        170        180 
RLYYYWERDY RRALCRLSQA GARVKIMDDE EFAYCWENFV YSEGQPFMPW YKFDDNYAFL 
       190        200        210        220        230        240 
HRTLKEILRN PMEAMYPHIF YFHFKNLRKA YGRNESWLCF TMEVVKHHSP VSWKRGVFRN 
       250        260        270        280        290        300 
QVDPETHCHA ERCFLSWFCD DILSPNTNYE VTWYTSWSPC PECAGEVAEF LARHSNVNLT 
       310        320        330        340        350        360 
IFTARLYYFW DTDYQEGLRS LSQEGASVEI MGYKDFKYCW ENFVYNDDEP FKPWKGLKYN 
       370    
FLFLDSKLQE ILE

Isoforms

- Isoform 2 of DNA dC->dU-editing enzyme APOBEC-3F - Isoform 3 of DNA dC->dU-editing enzyme APOBEC-3F

Sequence View

        10         20         30         40         50         60 
MKPHFRNTVE RMYRDTFSYN FYNRPILSRR NTVWLCYEVK TKGPSRPRLD AKIFRGQVYS 
        70         80         90        100        110        120 
QPEHHAEMCF LSWFCGNQLP AYKCFQITWF VSWTPCPDCV AKLAEFLAEH PNVTLTISAA 
       130        140        150        160        170        180 
RLYYYWERDY RRALCRLSQA GARVKIMDDE EFAYCWENFV YSEGQPFMPW YKFDDNYAFL 
       190        200        210        220        230        240 
HRTLKEILRN PMEAMYPHIF YFHFKNLRKA YGRNESWLCF TMEVVKHHSP VSWKRGVFRN 
       250        260        270        280        290        300 
QVDPETHCHA ERCFLSWFCD DILSPNTNYE VTWYTSWSPC PECAGEVAEF LARHSNVNLT 
       310        320        330        340        350        360 
IFTARLYYFW DTDYQEGLRS LSQEGASVEI MGYKDFKYCW ENFVYNDDEP FKPWKGLKYN 
       370    
FLFLDSKLQE ILE         10         20         30         40         50         60 
MKPHFRNTVE RMYRDTFSYN FYNRPILSRR NTVWLCYEVK TKGPSRPRLD AKIFRGQVYS 
        70         80         90        100        110        120 
QPEHHAEMCF LSWFCGNQLP AYKCFQITWF VSWTPCPDCV AKLAEFLAEH PNVTLTISAA 
       130        140        150        160        170        180 
RLYYYWERDY RRALCRLSQA GARVKIMDDE EFAYCWENFV YSEGQPFMPW YKFDDNYAFL 
       190        200        210        220        230        240 
HRTLKEILRN PMEAMYPHIF YFHFKNLRKA YGRNESWLCF TMEVVKHHSP VSWKRGVFRN 
       250        260        270        280        290        300 
QVDPETHCHA ERCFLSWFCD DILSPNTNYE VTWYTSWSPC PECAGEVAEF LARHSNVNLT 
       310        320        330        340        350        360 
IFTARLYYFW DTDYQEGLRS LSQEGASVEI MGYKDFKYCW ENFVYNDDEP FKPWKGLKYN 
       370    
FLFLDSKLQE ILE



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8IUX4-1-unknown MKPHFR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8IUX4-1-unknown MKPHFR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt65929
    Q8IUX4-1-unknown MKPHFR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt65930

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QEILE 373 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)